CAS 72882-78-1

Fórmula: C20H19ClN4

InChI: InChI=1S/C20H19ClN4/c1-24(2)11-10-19-22-23-20-13-16(14-6-4-3-5-7-14)17-12-15(21)8-9-18(17)25(19)20/h3-9,12-13H,10-11H2,1-2H3

Clave InChI: LYLASWLQCMKZAT-UHFFFAOYSA-N

SMILES: CN(C)CCC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=C2)C4=CC=CC=C4

PF-9366

CAS: 72882-78-1

Fórmula: C₂₀H₁₉ClN₄

Pureza: 98%

Forma y color: Solid

Peso molecular: 350.8447

Ref: IN-DA01E9V8

2-(7-Chloro-5-Phenyl-[1,2,4]Triazolo[4,3-A]Quinolin-1-Yl)-N,N-Dimethylethan-1-Amine

CAS: 72882-78-1

2-(7-Chloro-5-Phenyl-[1,2,4]Triazolo[4,3-A]Quinolin-1-Yl)-N,N-Dimethylethan-1-Amine

Fórmula: C₂₀H₁₉ClN₄

Pureza: 98%

Peso molecular: 350.84

Ref: 54-OR1023005

PF-9366

CAS: 72882-78-1

PF-9366

Fórmula: C₂₀H₁₉ClN₄

Pureza: ≥95%

Peso molecular: 350.84

Ref: 54-BUP08523

PF-9366

CAS: 72882-78-1

2-(7-Chloro-5-phenyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)-N,N-dimethylethan-1-amine

Fórmula: C₂₀H₁₉ClN₄

Pureza: 98%

Peso molecular: 350.84

Ref: IN-DG767474

PF-9366

CAS: 72882-78-1

PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM).

Fórmula: C₂₀H₁₉ClN₄

Pureza: 97.28% - 99.89%

Forma y color: Solid

Peso molecular: 350.84

Ref: TM-T5191

PF 9366

CAS: 72882-78-1

An allosteric inhibitor of human methionine adenosyltransferase 2A (Mat2A), the extrahepatic isoform, with an IC50 value of 420nM. Binding of PF9366 to Mat2A overlaps with the binding site of Mat2B, a regulator of Mat2A. Mat2A inhibition in cells by PF 9366 reduces synthesis of S-adenosylmethionine (SAM).

Fórmula: C₂₀H₁₉ClN₄

Pureza: Min. 95%

Forma y color: Solid

Peso molecular: 350.84 g/mol

Ref: 3D-BP164086

2-(7-Chloro-5-phenyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)-N,N-dimethylethan-1-amine

CAS: 72882-78-1

Pureza: 98%

Peso molecular: 350.8500061

Ref: 10-F870383