CAS 72956-09-3
:Carvedilol
Descripción:
Carvedilol es un antagonista beta-adrenérgico no selectivo y bloqueador alfa-1, utilizado principalmente en el manejo de la hipertensión y la insuficiencia cardíaca. Su fórmula química es C24H26N2O4, y presenta una estructura compleja que incluye un grupo fenólico y un centro quiral, lo que contribuye a su actividad farmacológica. Carvedilol exhibe propiedades antioxidantes y se ha demostrado que mejora la función del ventrículo izquierdo en pacientes con insuficiencia cardíaca. Actúa bloqueando los efectos de la adrenalina en el corazón y los vasos sanguíneos, lo que lleva a una disminución de la frecuencia cardíaca y la presión arterial. La sustancia se administra típicamente por vía oral y se absorbe bien, con una biodisponibilidad que puede verse influenciada por la ingesta de alimentos. Carvedilol generalmente es bien tolerado, pero los efectos secundarios potenciales pueden incluir mareos, fatiga e hipotensión. Sus efectos terapéuticos se atribuyen a su capacidad para reducir la carga cardíaca y mejorar la hemodinámica, lo que lo convierte en un medicamento valioso en la terapia cardiovascular.
Fórmula:C24H26N2O4
InChI:InChI=1S/C24H26N2O4/c1-28-21-10-4-5-11-22(21)29-14-13-25-15-17(27)16-30-23-12-6-9-20-24(23)18-7-2-3-8-19(18)26-20/h2-12,17,25-27H,13-16H2,1H3
Clave InChI:InChIKey=OGHNVEJMJSYVRP-UHFFFAOYSA-N
SMILES:O(CC(CNCCOC1=C(OC)C=CC=C1)O)C2=C3C=4C(NC3=CC=C2)=CC=CC4
Sinónimos:- (.+-.)-Carvedilol
- 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol
- 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]propan-2-ol
- Artist
- Bm 14190
- Cadilan
- Carca
- Cardivas
- Carloc
- Carvas
- Carvediol
- Carvexal
- Carvil
- Coreg
- Coronis
- Dilatrend
- Dimitone
- Dq 2466
- Eucardic
- Korvasan
- Kredex
- Querto
- Skf 105517
- Talliton
- Carvedilo
- CarvedilolEp5
- caredilol
- CarvedilolEdmf/Gmp
- 2-Propanol, 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-
- 1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol 2,3-dihydroxybutanedioate (salt)
- Carvediloledmf/Gmpep5
- CarvedilolC24H26N204
- 1-(9h-carbozol-4-yloxy)-3-[[2-(2-methoxy phenoxy)ethyl] amino]-2-propanol
- Ver más sinónimos
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Encontrado 18 productos.
Carvedilol
CAS:Fórmula:C24H26N2O4Pureza:>98.0%(T)(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:406.48CARVEDILOL CRS
CAS:CARVEDILOL CRSFórmula:C24H26N2O4Forma y color:Added ModifiedPeso molecular:406.4742CARVEDILOL FOR SYSTEM SUITABILITY CRS
CAS:CARVEDILOL FOR SYSTEM SUITABILITY CRSFórmula:C24H26N2O4Forma y color:Added ModifiedPeso molecular:406.4742Carvedilol
CAS:Cardiovascular drugs, nesoiFórmula:C24H26N2O4Forma y color:White Off-White Crystalline PowderPeso molecular:406.18926Carvedilol
CAS:<p>Carvedilol (SKF 105517) Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity. The S enantiomer of carvedilol nonselectively binds to and blocks beta-adrenergic receptors, thereby exerting negative inotropic and chronotropic effects, and leading to a reduction in cardiac output. In addition, both enantiomers of carvedilol bind to and block alpha 1-adrenergic receptors, thereby causing vasodilation and reducing peripheral vascular resistance.</p>Fórmula:C24H26N2O4Pureza:99.73% - 99.97%Forma y color:Colourless Crystalline PowderPeso molecular:406.47Carvedilol
CAS:Fórmula:C24H26N2O4Pureza:≥ 98.0% (dried basis)Forma y color:White or almost white crystalline powderPeso molecular:406.47Carvedilol
CAS:Producto controlado<p>Applications Carvedilol is a nonselective β-adrenergic blocker with α1-blocking activity. Carvedilol is an antihypertensive used in the treatment of congestive heart failure.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990); Packer, M., et al.: N. Engl. J. Med., 334, 1349 (1996);<br></p>Fórmula:C24H26N2O4Forma y color:WhitePeso molecular:406.47Carvedilol - Bio-X ™
CAS:Producto controlado<p>Carvediol is a nonselective beta-adrenoceptor blocking agent and an alpha 1-adrenoceptor blocker. It can be used as a drug, belonging to the class of beta blockers, in the treatment of heart failure, coronary artery disease, and hypertension. Carvedilol has been shown to reduce the risk of death in patients with heart failure and improve symptoms. Furthermore it has an effect on blood pressure by decreasing peripheral vascular resistance and mean arterial pressure. Carvedilol can be metabolized by cytochrome P450 enzymes and CYP2D6 and CYP2C9 liver enzymes.</p>Fórmula:C24H26N2O4Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:406.47 g/molCarvedilol
CAS:Producto controladoCarvediol is a nonselective beta-adrenoceptor blocking agent and an alpha 1-adrenoceptor blocker. It can be used as a drug, belonging to the class of beta blockers, in the treatment of heart failure, coronary artery disease, and hypertension. Carvedilol has been shown to reduce the risk of death in patients with heart failure and improve symptoms. Furthermore it has an effect on blood pressure by decreasing peripheral vascular resistance and mean arterial pressure. Carvedilol can be metabolized by cytochrome P450 enzymes and CYP2D6 and CYP2C9 liver enzymes.Fórmula:C24H26N2O4Pureza:Min. 98.5 Area-%Forma y color:White Off-White PowderPeso molecular:406.47 g/mol1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol
CAS:Fórmula:C24H26N2O4Pureza:98%Forma y color:SolidPeso molecular:406.4742
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