CAS 72957-38-1

fragmento de dinorfina A 1-13

Descripción:

fragmento de dinorfina A 1-13 es un péptido derivado de la molécula más grande de dinorfina A, que forma parte de la familia de péptidos opioides endógenos. Este fragmento consta de 13 aminoácidos y es conocido por su papel en la modulación del dolor, las respuestas al estrés y varios procesos neurofisiológicos. Interactúa principalmente con los receptores kappa-opioides en el sistema nervioso central, contribuyendo a sus efectos analgésicos. El péptido exhibe características típicas de los péptidos opioides, incluida la capacidad de inducir analgesia e influir en el estado de ánimo y las respuestas emocionales. Su estructura incluye secuencias específicas que son cruciales para la unión y actividad del receptor. Además, fragmento de dinorfina A 1-13 puede tener implicaciones en diversas condiciones neurológicas y es de interés en la investigación relacionada con la adicción, la depresión y otros trastornos del estado de ánimo. Como péptido sintético o de origen natural, se puede estudiar por sus propiedades farmacológicas y posibles aplicaciones terapéuticas.

Fórmula: C₇₅H₁₂₆N₂₄O₁₅

InChI: InChI=1/C75H126N24O15/c1-7-45(6)61(70(111)94-53(25-17-35-87-75(83)84)71(112)99-36-18-26-58(99)69(110)93-50(21-11-13-31-76)64(105)96-56(38-44(4)5)67(108)95-54(72(113)114)22-12-14-32-77)98-65(106)52(24-16-34-86-74(81)82)91-63(104)51(23-15-33-85-73(79)80)92-66(107)55(37-43(2)3)97-68(109)57(40-46-19-9-8-10-20-46)90-60(102)42-88-59(101)41-89-62(103)49(78)39-47-27-29-48(100)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,100H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H,88,101)(H,89,103)(H,90,102)(H,91,104)(H,92,107)(H,93,110)(H,94,111)(H,95,108)(H,96,105)(H,97,109)(H,98,106)(H,113,114)(H4,79,80,85)(H4,81,82,86)(H4,83,84,87)/t45-,49-,50-,51-,52-,53-,54?,55-,56-,57-,58-,61-/m0/s1

SMILES: CC[C@H](C)[C@@H](C(=N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=N[C@@H](CCCCN)C(=N[C@@H](CC(C)C)C(=NC(CCCCN)C(=O)O)O)O)O)O)N=C([C@H](CCCNC(=N)N)N=C([C@H](CCCNC(=N)N)N=C([C@H](CC(C)C)N=C([C@H](Cc1ccccc1)N=C(CN=C(CN=C([C@H](Cc1ccc(cc1)O)N)O)O)O)O)O)O)O

Sinónimos:

• Dynorphin A (1-13)
• H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH
• Dynorphin A 1-13, Porcine

Dynorphin A (1-13)

CAS: 72957-38-1

Endogenous kappa-opioid receptor agonist. It is suggested that it attenuates galanin-induced impairment of memory processes through the mediation of kappa-opioid receptors.

Fórmula: C₇₅H₁₂₆N₂₄O₁₅

Pureza: 91.6%

Forma y color: White Powder

Peso molecular: 1603.98

Ref: 01-4004062

Dynorphin A (1-13) H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH

CAS: 72957-38-1

Fórmula: C₇₅H₁₂₆N₂₄O₁₅

Pureza: 98%

Peso molecular: 1603.9547

Ref: IN-DA01E9V2

Dynorphin A (1-13) Acetatexa0

CAS: 72957-38-1

Ref: 7W-GX0937

Dynorphin A(1-13) Acetate

CAS: 72957-38-1

Fórmula: C₇₅H₁₂₆N₂₄O₁₅

Pureza: 95%~99%

Forma y color: White to Off-white Powder

Peso molecular: 1603.97

Ref: BP-BPPG022

Porcine dynorphin A(1-13)

CAS: 72957-38-1

Porcine dynorphin A (1-13) is a potent κ opioid receptor agonist; it's antinociceptive and raises [Ca2+]i in neurons like NMDA.

Fórmula: C₇₅H₁₂₆N₂₄O₁₅

Pureza: 98%

Forma y color: Solid

Peso molecular: 1603.95

Ref: TM-TP1179

Porcine Dynorphin A(1-13)

CAS: 72957-38-1

Porcine Dynorphin A(1-13)

Pureza: 99%

Peso molecular: 1,603.95g/mol

Ref: 54-BISN0009

Dynorphin A (1-13)

CAS: 72957-38-1

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Fórmula: C₇₅H₁₂₆N₂₄O₁₅

Peso molecular: 1,603.95 g/mol

Ref: 3D-PP50465

Dynorphin A (1-12), porcine

CAS: 72957-38-1

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Fórmula: C₆₉H₁₁₄N₂₂O₁₄

Peso molecular: 1,475.82 g/mol

Ref: 3D-PP50361

Dynorphin A (Human, 1-13)

CAS: 72957-38-1

As a dynorphin peptide, Dynorphin A has affinity for opioid receptors in particular it favors kappa-opioid receptors and residues 1-13 of the Dynorphin A peptide are crucial for its potency. Kappa-opioid receptors are expressed in the brain, peripheral tissues and the spinal cord and are located in areas involved in pain. For example when Dynorphin A binds to kappa-opioid receptors, dopamine is inhibited in areas of the brain prevalent in drug addiction, thus demonstrated Dynorphin A to have antagonistic effects on the brain reward circuit. Dynorphin A could be a useful research tool for studying analgesia, reward and addiction.
This product is available as a 0.5mg vial.

Fórmula: C₇₅H₁₂₆N₂₄O₁₅

Pureza: Min. 95%

Peso molecular: 1,604 g/mol

Ref: 3D-PDY-4080-V

Dynorphin A (porcine 1-13) - acetate salt

CAS: 72957-38-1

Dynorphin A (1-13) H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys is a peptide that is found in the brain and spinal cord. It is an agonist of opioid receptors, which are involved in pain relief, as well as motor control. Dynorphin A (1-13) H has been shown to inhibit acetylcholine release, which may be due to its ability to bind to kappa opioid receptors. Dynorphin A (1-13) H is also known to bind to κ opioid receptors, where it inhibits locomotor activity and induces analgesia.

Fórmula: C₇₅H₁₂₆N₂₄O₁₅

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 1,603.96 g/mol

Ref: 3D-FD108725

Dynorphin A (1-13), Porcine

CAS: 72957-38-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Forma y color: Lyophilized powder

Ref: 02-J64015