CAS 73231-34-2

Florfenicol

Descripción:

Florfenicol es un antibiótico sintético que pertenece a la clase de los fenicoles, utilizado principalmente en medicina veterinaria para el tratamiento de infecciones bacterianas en animales. Es efectivo contra un amplio espectro de bacterias Gram-positivas y Gram-negativas, lo que lo convierte en un agente terapéutico valioso. Florfenicol actúa inhibiendo la síntesis de proteínas bacterianas, dirigiéndose específicamente a la subunidad ribosomal 50S, lo que interrumpe la producción de proteínas esenciales necesarias para el crecimiento y la reproducción bacteriana. La sustancia se caracteriza por su toxicidad relativamente baja en animales en comparación con otros antibióticos, lo que permite su uso en animales de producción de alimentos bajo condiciones reguladas. Florfenicol se administra típicamente por inyección o en formulaciones de alimentación, y su farmacocinética indica una buena penetración en los tejidos, lo que es beneficioso para el tratamiento de infecciones sistémicas. Sin embargo, su uso está sujeto a estrictas regulaciones debido a preocupaciones sobre la resistencia a los antibióticos y los posibles residuos en los productos alimenticios. En general, Florfenicol representa una herramienta importante en la medicina veterinaria, equilibrando la eficacia contra las infecciones bacterianas con consideraciones de seguridad y cumplimiento regulatorio.

Fórmula: C₁₂H₁₄Cl₂FNO₄S

InChI: InChI=1/C12H14Cl2FNO2S/c1-19-8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)

Clave InChI: InChIKey=AYIRNRDRBQJXIF-NXEZZACHSA-N

SMILES: [C@@H]([C@H](NC(C(Cl)Cl)=O)CF)(O)C1=CC=C(S(C)(=O)=O)C=C1

Sinónimos:

• 2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
• 2,2-Dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
• 2,2-dichloro-N-{(1R,2S)-3-fluoro-1-hydroxy-1-[4-(methylsulfonyl)phenyl]propan-2-yl}acetamide
• 2,2-dichloro-N-{1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfanyl)phenyl]ethyl}acetamide
• Acetamide, 2,2-dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]-
• Acetamide, 2,2-dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]-, [R-(R*,S*)]-
• Aquafen
• Aquaflor
• Flofenicol
• Flonicol
• Florfeniol
• Florgane
• Floron
• Nuflor
• Sch 25298
• Selectan
• Topazone
• Florfenicol
• [R-(R*,S*)]-2,2-DICHLORO-N-[1-(FLUOROMETHYL)-2-HYDROXY-2-[4-(METHYLSULFONYL)PHENYL]ETHYL]ACETAMIDE
• Fluorothiamphenicol
• [r-(r*, r*)]-n-[1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulforyl)phenyl)-ethyl]-2,2-dichloroacetamide
• Sch-25298, Aquafen
• (r-(r*,s*))-methyleste
• 2,2-dichloro-n-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl
• 2,2-Dichloro-N-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)acetamide
• Acetamide, 2,2-dichloro-N-(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-4-(methylsulfonyl)phenylethyl-
• FLUPROFEN
• Aquafen, Nuflor, SCH-25298, [R-(R*,S*)]-2,2-Dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
• 2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamid

Florfenicol

CAS: 73231-34-2, 76639-94-6

Fórmula: C₁₂H₁₄Cl₂FNO₄S

Pureza: >98.0%(HPLC)(N)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 358.21

Ref: 3B-F0811

Florfenicol, 98%

CAS: 73231-34-2

A bacteriostatic antibiotic similar to chloramphenicol which inhibits bacterial protein synthesis This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar pr

Fórmula: C₁₂H₁₄Cl₂FNO₄S

Pureza: 98%

Forma y color: White to pale cream, Powder or crystalline powder

Peso molecular: 358.21

Ref: 02-J66995

Acetamide, 2,​2-​dichloro-​N-​[(1S,​2R)​-​1-​(fluoromethyl)​-​2-​hydroxy-​2-​[4-​(methylsulfonyl)​phenyl]​ethyl]​-

CAS: 73231-34-2

Fórmula: C₁₂H₁₄Cl₂FNO₄S

Pureza: %

Forma y color: Solid

Peso molecular: 358.2133

Ref: IN-DA00ICDO

Florfenicol

CAS: 73231-34-2

Florfenicol treats bovine respiratory disease and foot rot in cattle, and catfish enteric septicemia.

Fórmula: C₁₂H₁₄Cl₂FNO₄S

Pureza: 99.22% - 99.33%

Forma y color: White Crystalline Powder

Peso molecular: 358.21

Ref: TM-T0454L

Florfenicol

CAS: 73231-34-2

Florfenicol

Pureza: 98%

Peso molecular: 358.21g/mol

Ref: 54-PC109152

Florfenicol

CAS: 73231-34-2

Fórmula: C₁₂H₁₄Cl₂FNO₄S

Forma y color: White To Off-White Solid

Peso molecular: 358.22

Ref: 4Z-F-231

Florfenicol

CAS: 73231-34-2

Fórmula: C₁₂H₁₄Cl₂FNO₄S

Pureza: ≥ 98.0% (dried basis)

Forma y color: White to off-white powder

Peso molecular: 358.21

Ref: 7W-GA3827

Florfenicol

Producto controlado

CAS: 73231-34-2

Fórmula: C₁₂H₁₄Cl₂FNO₄S

Forma y color: Neat

Peso molecular: 358.21

Ref: 04-C13665000

Florfenicol-d5

CAS: 73231-34-2

Fórmula: C₁₂H₉D₅Cl₂FNO₄S

Forma y color: White To Off-White Solid

Peso molecular: 363.24

Ref: 4Z-F-2314

Florfenicol

CAS: 73231-34-2

Applications Florfenicol is a fluorinated derivative of thiamphenicol. Florfenicol inhibits bacterial protein synthesis by binding to ribosome 50S and 70S subunits. Florfenicol is used as an antibacterial.
References Kim, E and Aoki, T.: Microbiol. Immunol., 40, 665, (1996), Keyes, K.: Antimicrob. Agents Chemother., 44, 421 (2000)

Fórmula: C₁₂H₁₄Cl₂FNO₄S

Forma y color: Yellow

Peso molecular: 358.21

Ref: TR-F405750

Florfenicol

CAS: 73231-34-2

Florfenicol is a broad-spectrum antibiotic that belongs to the group of florfenicol. It is used in veterinary medicine to treat bacterial infections in animals, including those caused by salmonella, streptococcus, and mycoplasma. Florfenicol has been shown to have an inhibitory effect on the growth of tetracycline-resistant bacteria. Florfenicol binds reversibly to the 23S ribosomal RNA in the 50S subunit of bacteria and inhibits protein synthesis. This binding prevents the formation of an antibiotic-inhibitor complex with the enzyme ribosome that is required for translation, inhibiting protein synthesis and cell division. The rate constant for this reaction has been determined using a combination of analytical methods, including chromatographic analysis and colloidal gold electrophoresis. Florfenicol also has anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis.

Fórmula: C₁₂H₁₄Cl₂FNO₄S

Pureza: Min. 98 Area-%

Forma y color: White Powder

Peso molecular: 358.21 g/mol

Ref: 3D-FF23306

Florfenicol - Bio-X ™

CAS: 73231-34-2

Florfenicol is a broad-spectrum antibiotic used for the treatment of various bacteria infections. This drug is used in veterinary medicine and to treat animals with those infections. This drug works by inhibiting bacteria synthesis. It is a fluorinated synthetic analog of thiamphenicol.

Fórmula: C₁₂H₁₄Cl₂FNO₄S

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 358.21 g/mol

Ref: 3D-BF166386

Florfenicol

CAS: 73231-34-2

Pureza: 99+%

Peso molecular: 357

Ref: 10-F801753