CAS 742075-03-2

(5α)-4,5-Epoxy-14-hydroxy-3-methoxy-6-oxomorphinan-17-carboxylic Acid 1,1-Dimethylethyl Ester

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CAS: 742075-03-2

Applications (5α)-4,5-Epoxy-14-hydroxy-3-methoxy-6-oxomorphinan-17-carboxylic Acid 1,1-Dimethylethyl Ester is an intermediate in the synthesis of Nalfurafine (N255600), which is a κ-opioid receptor agonist marketed as a treatment for uremic pruritus in hemodialysis patients.
References Kawamura, K., et al.: Chem. Pharma. Bull., 52, 670 (2004); Heydari, A., et al.: Tetrahedron. Lett., 48, 5865 (2007);

Fórmula: C₂₂H₂₇NO₆

Forma y color: Beige

Peso molecular: 401.45

Ref: TR-E589275