CAS 74397-12-9
:Limaprost
Descripción:
Limaprost es un análogo sintético de prostaglandinas utilizado principalmente por sus efectos vasodilatadores, particularmente en el tratamiento de enfermedades vasculares periféricas y condiciones asociadas con un flujo sanguíneo deficiente. Se caracteriza por su capacidad para mejorar la circulación sanguínea al relajar el músculo liso vascular, lo que puede llevar a una mejor entrega de oxígeno a los tejidos. Limaprost se administra a menudo en forma de tabletas orales o inyecciones, dependiendo de la indicación clínica. La sustancia presenta una vida media relativamente corta, lo que requiere un dosificación cuidadosa para mantener niveles terapéuticos. Su mecanismo de acción implica la activación de receptores específicos de prostaglandinas, que median diversas respuestas fisiológicas, incluida la inhibición de la agregación plaquetaria y la modulación de procesos inflamatorios. Además, Limaprost puede tener efectos secundarios como dolor de cabeza, rubor o trastornos gastrointestinales, que deben ser monitoreados durante el tratamiento. Al igual que con cualquier medicamento, su uso debe ser guiado por un profesional de la salud, considerando el estado de salud general del paciente y las posibles interacciones medicamentosas.
Fórmula:C22H36O5
InChI:InChI=1/C22H36O5/c1-3-4-9-16(2)14-17(23)12-13-19-18(20(24)15-21(19)25)10-7-5-6-8-11-22(26)27/h8,11-13,16-19,21,23,25H,3-7,9-10,14-15H2,1-2H3,(H,26,27)/b11-8+,13-12+/t16-,17+,18+,19+,21+/m0/s1
Clave InChI:InChIKey=OJZYRQPMEIEQFC-UAWLTFRCSA-N
SMILES:C(CCC/C=C/C(O)=O)[C@@H]1[C@@H](/C=C/[C@H](C[C@H](CCCC)C)O)[C@H](O)CC1=O
Sinónimos:- (2E)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonen-1-yl]-5-oxocyclopentyl]-2-heptenoic acid
- (2E)-7-{(1R,2R,3R)-3-Hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonen-1-yl]-5-oxocyclopentyl}-2-heptenoic acid (non-preferred name)
- (E)-7-((1R,2R,3R)-3-Hydroxy-2-((E)-(3S,5S)-3-hydroxy-5-methyl-1-nonenyl)-5-oxocyclopentyl)-2-heptenoic acid
- (E)-7-((1R,2R,3R)-3-Hydroxy-2-((E)-(3S,5S)-3-hydroxy-5-methyl-1-nonenyl)-5-oxocyclopentyl)-2-heptenoic acid 17S-Methyl-w-homo-trans-D2-PGE1
- 17S,20-Dimethyl-trans-D2-PGE1
- 17S,20-Dimethyl-trans-Δ<sup>2</sup>-PGE<sub>1</sub>
- 17S-Methyl-w-homo-trans-D2-PGE1
- 2-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonen-1-yl]-5-oxocyclopentyl]-, (2E)-
- 2-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonenyl]-5-oxocyclopentyl]-, (2E)-
- 2-Heptenoicacid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonenyl]-5-oxocyclopentyl]-,(2E)-
- 2E,11a,13E,15S,17S)-11,15-Dihydroxy-17,20-dimethyl-9-oxoprosta-2,13-dien-1-oic Acid
- 9-Oxo-11a,15a-dihydroxy-17S,20-dimethylprosta-trans-2,trans-13-dienoic Acid
- Limaprost
- Ono 1206
- Op 1206
- Op1206
- Prosta-2,13-dien-1-oic acid,11,15-dihydroxy-17,20-dimethyl-9-oxo-, (2E,11a,13E,15S,17S)-
- 17α,20-dimethyl-δ2-PGE1
- n-1-oicacid
- 11ALPHA, 15S-DIHYDROXY-17S,20-DIMETHYL-9-OXO-PROSTA-2E, 13E-DIEN-1-OIC ACID
- D02722
- ,13e,15s,17s)-
- 17A,20-DIMETHYL-D2-PGE1
- 9-oxo-11-alpha,15-alpha-dihydroxy-17s,20-dimethylprosta-trans-2,trans-13-die
- (2E,11R,13E,15S,17S)-11α,15-Dihydroxy-17,20-dimethyl-9-oxoprosta-2,13-dien-1-oic acid
- 11A,15S-DIHYDROXY-17S,20-DIMETHYL-9-OXO-PROSTA-2E,13E-DIEN-1-OIC ACID
- ono1206
- (2e,11-alpha,13e,15s,17s)-11,15-dihydroxy-17,20-dimethyl-9-oxoprost-2,13-die
- 17α,20-dimethyl-δ2-PGE1, 11α,15S-Dihydroxy-17S,20-dimethyl-9-oxo-prosta-2E,13E-dien-1-oic acid
- (2E)-7-[(1R)-2β-[(1E,3S,5S)-3-Hydroxy-5-methyl-1-nonenyl]-3α-hydroxy-5-oxocyclopentan-1α-yl]-2-heptenoic acid
- 2-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonenyl]-5-oxocyclopentyl]-, (2E)-(9CI)
- 17s,20-dimethyl-trans-2,3-didehydro-pge1
- prost-2,13-dien-1-oicacid,11,15-dihydroxy-17,20-dimethyl-9-oxo-,(2e,11-alpha
- 11α,15s-dihydroxy-17s,20-dimethyl-9-oxo-prosta-2e,13e-dien-1-oic acid
- Ver más sinónimos
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Encontrado 9 productos.
Limaprost
CAS:Fórmula:C22H36O5Pureza:≥ 99.0%Forma y color:White to off-white powderPeso molecular:380.52Limaprost
CAS:Limaprost (17α,20-dimethyl-δ2-PGE1) is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency.It is aFórmula:C22H36O5Pureza:99.61% - 99.89%Forma y color:SolidPeso molecular:380.52Limaprost
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Limaprost is an analog of Prostaglandin E1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is used as an antianginal.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tsuboi, T., et al.: Arch. Int. Pharmacodyn., 247, 89 (1980), Adaikan, P.G., et al.: Prostaglandins Med., 6, 449 (1981), Kottegoda, S.R., et al.: Prostaglandins Leukotrienes Med., 8, 343 (1982), Ishizaki, T., et al.: Chest, 85, 382 (1984),<br></p>Fórmula:C22H36O5Forma y color:NeatPeso molecular:380.52Limaprost
CAS:<p>Limaprost is a nonsteroidal anti-inflammatory drug (NSAID) that belongs to the group of coumarin derivatives. It is used in the treatment of diabetic neuropathy, and has also been shown to reduce blood levels of cholesterol. Limaprost can be administered orally or topically, and blocks prostaglandin synthesis by inhibiting cyclooxygenase. Limaprost is available as a tablet and injection for oral use. The drug is also used for relief of pain in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and other musculoskeletal disorders. Limaprost is metabolized by esterases in the liver to form desacetyllimaprost (DALP), which has approximately one-third the potency of limaprost. DALP's metabolites are excreted primarily through bile into the intestine, where they are reabsorbed back into the bloodstream. They are then</p>Fórmula:C22H36O5Pureza:Min. 95%Forma y color:PowderPeso molecular:380.52 g/mol
