CAS 7535-72-0

Z-Gly-Leu-NH2

Descripción:

Z-Gly-Leu-NH2, también conocido como Z-Glicil-Leucina amida, es un derivado peptídico caracterizado por su secuencia específica de aminoácidos y grupo protector. La "Z" denota un grupo protector benzyloxycarbonilo (Cbz) en el residuo de glicina, que mejora la estabilidad y solubilidad. Este compuesto presenta una secuencia de aminoácidos de glicina (Gly) y leucina (Leu), con un grupo amida (-NH2) en el extremo C, que puede influir en su actividad biológica y solubilidad. Z-Gly-Leu-NH2 se utiliza típicamente en la síntesis de péptidos y en investigación, particularmente en estudios relacionados con hormonas peptídicas, neurotransmisores y desarrollo de fármacos. Sus propiedades incluyen ser un sólido blanco a blanco sucio, soluble en disolventes polares y exhibir estabilidad bajo condiciones de laboratorio estándar. La presencia del grupo amida también puede impartir interacciones específicas en sistemas biológicos, lo que lo hace de interés en aplicaciones farmacológicas. En general, Z-Gly-Leu-NH2 sirve como un compuesto valioso en el campo de la bioquímica y la química medicinal.

Fórmula: C₁₆H₂₃N₃O₄

Sinónimos:

• L-Leucinamide, N-[(phenylmethoxy)carbonyl]glycyl-
• Carbamicacid, [[(1-carbamoyl-3-methylbutyl)carbamoyl]methyl]-, benzyl ester
• Carbamic acid, [[(1-carbamoyl-3-methylbutyl)carbamoyl]methyl]-, benzyl ester,L-
• Leucinamide, N-carboxyglycyl-, benzyl ester, L-
• Benzyloxycarbonylglycyl-L-leucinamide
• N-(Benzyloxycarbonyl)glycyl-L-leucinamide
• N-Benzyloxycarbonylglycyl-L-leucineamide
• N-Carbobenzoxy-glycyl-leucine amide
• N-Carbobenzoxyglycyl-L-leucinamide

Z-Gly-Leu-NH2

CAS: 7535-72-0

Z-Gly-Leu-NH2 is a peptide that has been shown to have specificities against the bacteria Staphylococcus. It was obtained by the synthesis of a synthetic peptide with a sequence corresponding to the amino acid sequence of casein, which is a protein found in milk. The peptide contains four amino acids and has been shown to induce cytopathic effect in staphylococci, which are rod-shaped bacteria. This peptide also has high thermostability, which means it can be heated up to 100°C for 10 minutes without changing its activity. Z-Gly-Leu-NH2 is stable at pH 5 and is resistant to proteolytic degradation by subtilisin, making it an ideal candidate for use as a food additive.

Fórmula: C₁₆H₂₃N₃O₄

Pureza: Min. 95%

Peso molecular: 321.37 g/mol

Ref: 3D-SGL-3037

Z-Gly-Leu-NH2

CAS: 7535-72-0

Z-Gly-Leu-NH2 is a synthetic peptide that has been designed to mimic the amino acid sequence of casein. It is a metalloendopeptidase inhibitor and can be used in the synthesis of proteins. Z-Gly-Leu-NH2 inhibits the activity of subtilisin, which is a proteolytic enzyme. The inhibition of subtilisin by Z-Gly-Leu-NH2 prevents the hydrolysis of peptide bonds in protein substrates. This inhibition leads to an increase in molecular weight and molecular weight distribution, as well as an increase in the number of high molecular weight peaks on chromatograms. This peptide also has serine protease inhibitory activity and can be used as a synthetic substrate for kinetic studies.

Fórmula: C₁₆H₂₃N₃O₄

Pureza: Min. 95%

Peso molecular: 321.37 g/mol

Ref: 3D-FG111477