CAS 76-42-6

(-)-Oxycodona

Descripción:

(-)-Oxycodona, con el número CAS 76-42-6, es un analgésico opioide semisintético derivado de la tebaína, un alcaloide natural que se encuentra en la adormidera. Se utiliza principalmente para el manejo del dolor moderado a severo, a menudo en casos donde otros métodos de alivio del dolor son insuficientes. La sustancia exhibe una estructura química compleja que incluye un núcleo de fenantreno, lo que contribuye a sus potentes propiedades analgésicas. (-)-Oxycodona actúa principalmente como un agonista del receptor mu-opioide, lo que lleva a su efectividad en el alivio del dolor, pero también interactúa con los receptores opioides kappa y delta en menor medida. Se conoce que el compuesto tiene potencial de abuso y dependencia, lo que requiere una regulación y monitoreo cuidadosos en entornos clínicos. En términos de farmacocinética, (-)-Oxycodona se absorbe bien cuando se administra por vía oral, con una biodisponibilidad que puede variar según la formulación. Los efectos secundarios comunes incluyen sedación, estreñimiento y depresión respiratoria, lo que resalta la importancia de una dosificación cautelosa y la evaluación del paciente durante el tratamiento.

Fórmula: C₁₈H₂₁NO₄

InChI: InChI=1S/C18H21NO4/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10/h3-4,13,16,21H,5-9H2,1-2H3/t13-,16+,17+,18-/m1/s1

Clave InChI: InChIKey=BRUQQQPBMZOVGD-XFKAJCMBSA-N

SMILES: O[C@]12[C@@]34C=5C(O[C@]3(C(=O)CC1)[H])=C(OC)C=CC5C[C@]2(N(C)CC4)[H]

Sinónimos:

• (-)-Oxycodone
• (5α)-4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
• 14-Hydroxydihydrocodeinone
• 3-O-(Methyl)oxymorphone
• 4,5α-Epoxy-14-hydroxy-3-methoxy-17-methyl-6-morphinanone
• 6-Oxo-14-hydroxy-7,8-dihydrocodeine
• 7,8-Dihydro-14-hydroxycodeinone
• Codeinone, 7,8-dihydro-14-hydroxy-
• Dihydro-14-hydroxycodeinone
• Dihydrohydroxycodeinone
• Dihydrone
• Morphinan-6-one, 4,5α-epoxy-14-hydroxy-3-methoxy-17-methyl-
• Nsc 19043
• Oxicodona
• Oxicon
• Oxycodeinone
• Oxycodon
• Oxycodone DETERx
• Oxymorphone 3-methyl ether
• Oxynorm
• Pavinal
• Pti 821
• Remoxy
• Xtampza ER
• UNII-CD35PMG570
• Ossicodone [DCIT]
• Oxicodona [INN-Spanish]
• Dihydroxycodeinone
• Morphinan-6-one, 4,5alpha-epoxy-14-hydroxy-3-methoxy-17-methyl-
• HSDB 3142
• Oxanest
• Codeinone, dihydro-14-hydroxy-
• OxyIR
• DEA No. 9143
• Oxycodone Concentrate
• Eubine
• 4-27-00-03681 (Beilstein Handbook Reference)
• Endine (Australia)
• Oxycodonum
• 4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
• Oxyfast
• Eubine [France]
• Ossicodone
• Tylox
• BRN 0043446
• Endone
• Eucodalum
• Diphydrone
• Roxicodone
• Supendol [Canada]
• Morphinan-6-one, 4,5-epoxy-14-hydroxy-3-methoxy-17-methyl-, (5α)-
• Morphinan-6-one, 4,5-alpha-epoxy-14-hydroxy-3-methoxy-17-methyl-
• Supendol
• Pancodone retard (United Kingdom)
• Oxycodonum [INN-Latin]
• Percobarb
• 4,5alpha-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
• Percodan
• Roxicet
• Morphinan-6-one, 4,5-epoxy-14-hydroxy-3-methoxy-17-methyl-, (5alpha)-
• Percocet

Oxycodone 0.1 mg/ml in Methanol

Producto controlado

CAS: 76-42-6

Forma y color: Single Solution

Ref: 61-AMP0672.10-02

Oxycodone

Producto controlado

CAS: 76-42-6

Forma y color: Neat

Ref: 61-FOR0672.10

Oxycodone 1.0 mg/ml in Methanol

Producto controlado

CAS: 76-42-6

Forma y color: Single Solution

Ref: 61-AMP0672.10-01

Oxycodone

Producto controlado

CAS: 76-42-6

Fórmula: C₁₈H₂₁NO₄

Forma y color: Neat

Peso molecular: 315.36

Ref: 86-MM0672.10

Oxycodone

Producto controlado

CAS: 76-42-6

Applications Controlled substance (opiate). Analgesic (narcotic).
References Mendelson, J., et al.: Clin. Pharmacol. Ther., 60, 105 (1996); Fudala, P., et al.: N. Engl. J. Med., 349, 949 (2003); Alho, H., et al.: Drug Alcohol Depend., 88, 75 (2007)

Fórmula: C₁₈H₂₁NO₄

Forma y color: White

Peso molecular: 315.36

Ref: TR-O870605

1-Amino Oxycodone

Producto controlado

CAS: 76-42-6

Fórmula: C₁₈H₂₃N₂O₄·Cl

Forma y color: Neat

Peso molecular: 366.839

Ref: TR-A851870

Opiate Multi-component Mixture-5 (mixture of Codeine, Hydrocodone, Meperidine, (±)-Methadone and Oxycodone, 250 μg/mL of each component in methanol)

Producto controlado

CAS: 125-29-1, 57-42-1, 76-42-6, 76-57-3, 76-99-3

Fórmula: MixtureVisitourWebsite

Forma y color: Mixture

Peso molecular: Mixture - Visit our Website

Ref: TR-KIT2160

Oxycodone

Producto controlado

CAS: 76-42-6

Oxycodone is a synthetic opioid used to relieve moderate-to-severe pain. It is the most potent of the naturally occurring opiates and has a low potency in comparison to other opioids, such as morphine. Oxycodone is available as a single agent, but also in combination preparations with paracetamol or ibuprofen for relief of moderate-to-severe pain. Common side effects include nausea, vomiting, constipation, itching and sweating. Oxycodone has been shown to have significant drug interactions with nonsteroidal anti-inflammatory drugs (NSAIDs) and may be associated with an increased risk of gastrointestinal bleeding. Evidence suggests that oxycodone can decrease platelet aggregation by inhibiting cyclooxygenase activity and prolong bleeding time by interfering with platelet function through inhibition of thromboxane A2 synthesis. Oxycodone binds to kappa-opioid receptors, which are involved in the modulation of pain perception and mood regulation. The binding of

Fórmula: C₁₈H₂₁NO₄

Pureza: Min. 95%

Peso molecular: 315.36 g/mol

Ref: 3D-FO32141

Oxycodone CII

Producto controlado

CAS: 76-42-6

Concentrates of poppy straw; buprenorphine (inn) codeine, dihydrocodeine (inn), ethylmorphine (inn), etorphine (inn), heroin, hydrococdone (inn), etc.

Fórmula: C₁₈H₂₁NO₄

Forma y color: White Off-White Crystalline Powder

Peso molecular: 315.36 g/mol

Ref: 45-1485191