CAS 76144-81-5

Meldonium

Descripción:

Meldonium, también conocido como Mildronato, es un compuesto sintético utilizado principalmente como medicamento para tratar condiciones cardíacas isquémicas y mejorar el rendimiento físico. Fue desarrollado en la década de 1970 en Letonia y se clasifica como un modulador metabólico. La fórmula química de Meldonium es C5H13N1O2, y presenta una estructura única que incluye un anillo de 1,2,4-triazol. Meldonium actúa inhibiendo la enzima carnitina aciltransferasa, que juega un papel en el metabolismo de los ácidos grasos, promoviendo así la utilización de glucosa sobre los ácidos grasos para la producción de energía. Este cambio puede mejorar la resistencia y reducir la fatiga durante el esfuerzo físico. La sustancia ha ganado atención en el deporte debido a sus efectos de mejora del rendimiento, lo que ha llevado a su inclusión en la lista de sustancias prohibidas de la Agencia Mundial Antidopaje. Aunque generalmente es bien tolerada, los efectos secundarios potenciales pueden incluir dolores de cabeza, mareos y trastornos gastrointestinales. Su uso debe ser monitoreado, especialmente en individuos con condiciones de salud preexistentes.

Fórmula: C₆H₁₄N₂O₂

InChI: InChI=1/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5?,6-,7-,8?/m1/s1

Clave InChI: InChIKey=PVBQYTCFVWZSJK-UHFFFAOYSA-N

SMILES: N(CCC([O-])=O)[N+](C)(C)C

Sinónimos:

• 1,1,1-Trimethyl-2-(2-carboxyethyl)hydrazine zwitterion
• 2-(2-Carboxyethyl)-1,1,1-Trimethylhydrazinium Hydroxide Inner Salt
• 2-(2-Carboxyethyl)-1,1,1-trimethyl Hydrazinium Inner Salt
• 3-(2,2,2-Trimethylhydrazine)Propionate
• 3-(2,2,2-Trimethylhydrazinium)propionate
• 3-(Trimethylammonioamino)Propanoate
• 3-[(Trimethylazaniumyl)amino]propanoate
• Hydrazinium, 2-(2-carboxyethyl)-1,1,1-trimethyl-, inner salt
• Hydrinol
• Idrinol
• Meldomiun
• Meldonium
• Met 88
• Met88
• Mildonate
• Quateri
• Quaterin
• Vasonat
• Mildronate
• N-Trimethyl-hydrazine-3-propionate
• 1,1,1-Trimethylhydrazinium 2-propionate
• 3-[(Trimethylaminio)amino]propionic acidanion
• 2-(2-Carboxylatoethyl)-1,1,1-trimethylhydrazinium

1,1,1-Trimethyl-2-(2-carboxyethyl)hydrazine zwitterion

CAS: 76144-81-5

Fórmula: C₆H₁₄N₂O₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 146.1876

Ref: IN-DA00IKH3

Mildronate-d3

CAS: 76144-81-5

Fórmula: C₆H₁₁N₂O₂D₃

Forma y color: White To Off-White Solid

Peso molecular: 149.21

Ref: 4Z-M-511

Mildronate-d3 HCl

CAS: 76144-81-5

Fórmula: C₆H₁₁D₃N₂O₂·HCl

Forma y color: White To Off-White Solid

Peso molecular: 149.21 36.46

Ref: 4Z-M-515

Mildronate

CAS: 76144-81-5

Fórmula: C₆H₁₄N₂O₂

Pureza: ≥ 98.0%

Forma y color: White to off-white crystalline powder

Peso molecular: 146.19

Ref: 7W-GP7996

Mildronate

CAS: 76144-81-5

Fórmula: C₆H₁₄N₂O₂

Peso molecular: 146.19

Ref: 4Z-M-512

Mildronate

CAS: 76144-81-5

Mildronate (Meldonium) is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine

Fórmula: C₆H₁₄N₂O₂

Pureza: 99.94%

Forma y color: White Crystalline Powder

Peso molecular: 146.19

Ref: TM-T3268

Mildronate-d3

Producto controlado

CAS: 76144-81-5

Stability Very Hygroscopic
Applications Mildronate-d3 is the labeled analogue of Mildronate (M344450), a novel pharmaceutical composition based on a reverse transcriptase inhibitor and meldonium. May contain a significant amount of water.

Fórmula: C₆H₁₁D₃N₂O₂

Forma y color: White To Off-White

Peso molecular: 149.21

Ref: TR-M344452

Meldonium

Producto controlado

CAS: 76144-81-5

Mildronate is a drug with a matrix effect that has been shown to be effective in experimental models. Mildronate is used to treat cardiac arrhythmias and myocardial infarcts, as well as other cardiovascular diseases. Mildronate also has pharmacological effects on the brain, including protecting against brain toxicity and improving cognitive functions. The drug has been shown to have an effect on the blood pressure, energy metabolism, and pharmacological treatment of diseases. Mildronate was discovered during an analytical study of erythrocyte membranes and its effects were studied in detail. It was found that mildronate improved the membrane's stability and increased its resistance to hemolysis. This discovery led scientists to investigate mildronate as a possible treatment for heart conditions involving blood clots or low blood flow.

Fórmula: C₆H₁₄N₂O₂

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 146.19 g/mol

Ref: 3D-FM26003

Meldonium

Producto controlado

CAS: 76144-81-5

Meldonium is a cardiovascular drug, which is a synthetic compound originating from Latvia. It functions by modulating carnitine metabolism, leading to decreased fatty acid oxidation and augmented glucose oxidation. This shift in energy substrate helps to improve energy efficiency, particularly under conditions of ischemia, which can prevent ischemic damage by balancing oxygen supply and demand.

Fórmula: C₆H₁₄N₂O₂

Pureza: Min. 95 Area-%

Peso molecular: 146.19 g/mol

Ref: 3D-Q-201406