CAS: 763113-22-0 - Olaparib

Fórmula: C₂₄H₂₃FN₄O₃

InChI: InChI=1S/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26-21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5,8,13,16H,6-7,9-12,14H2,(H,27,30)

Clave InChI: InChIKey=FDLYAMZZIXQODN-UHFFFAOYSA-N

SMILES: O=C1NN=C(C=2C=CC=CC12)CC3=CC=C(F)C(=C3)C(=O)N4CCN(C(=O)C5CC5)CC4

Sinónimos:

• 1(2H)-Phthalazinone, 4-[[3-[[4-(cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-
• 1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine
• 4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one
• 4-[3-(4-Cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one
• 4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone
• Azd 2281
• Azd2281
• Ku 0059436
• Ku 59436
• Lynparza
• Piperazine, 1-(cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]-

Olaparib

CAS: 763113-22-0

• Fórmula: C₂₄H₂₃FN₄O₃
• Forma y color: White To Off-White Solid
• Peso molecular: 434.47

Olaparib

CAS: 763113-22-0

• Fórmula: C₂₄H₂₃FN₄O₃
• Pureza: (HPLC) ≥ 98.0%
• Forma y color: White to off-white powder
• Peso molecular: 434.46

Olaparib-d4

CAS: 763113-22-0

• Fórmula: C₂₄H₁₉D₄FN₄O₃
• Forma y color: White To Off-White Solid
• Peso molecular: 438.50

Olaparib

CAS: 763113-22-0

• Fórmula: C₂₄H₂₃FN₄O₃
• Forma y color: White
• Peso molecular: 434.46

Olaparib D5

CAS: 763113-22-0

Olaparib

CAS: 763113-22-0

Olaparib (KU0059436) is a small molecule inhibitor of PARP1/PARP2 (IC50=5/1 nM), with weak inhibitory activity …

• Fórmula: C₂₄H₂₃FN₄O₃
• Pureza: 100%
• Forma y color: Solid
• Peso molecular: 434.46

Olaparib-d4

CAS: 763113-22-0

• Fórmula: C₂₄H₁₉D₄FN₄O₃
• Forma y color: White to Off-White Solid
• Peso molecular: 438.49

4-[(3-{[4-Cyclopropylcarbonyl)piperazin-4-yl]carbonyl}-4-fluorophenyl)methyl]phtalazin-1(2H)-one

CAS: 763113-22-0

• Pureza: 95.0%
• Forma y color: Solid, Pale yellow crystal
• Peso molecular: 434.47100830078125

Olaparib

CAS: 763113-22-0

PARP polymerase inhibitor

• Fórmula: C₂₄H₂₃FN₄O₃
• Pureza: Min. 98 Area-%
• Forma y color: White Powder
• Peso molecular: 434.46 g/mol

Olaparib - Bio-X ™

CAS: 763113-22-0

Olaparib is a small molecule inhibitor of DNA polymerase and topoisomerase, which are enzymes that …

• Fórmula: C₂₄H₂₃FN₄O₃
• Pureza: Min. 95%
• Forma y color: Solid
• Peso molecular: 434.46 g/mol