CAS 76330-71-7

Altanserina

Descripción:

Altanserina es un compuesto químico reconocido principalmente por su papel como antagonista selectivo del receptor de serotonina 5-HT2A. A menudo se utiliza en la investigación farmacológica, particularmente en estudios relacionados con la neurofarmacología y la investigación de trastornos psiquiátricos. El compuesto tiene una estructura molecular compleja, que contribuye a su afinidad de unión específica por el receptor 5-HT2A, lo que lo convierte en una herramienta valiosa para comprender las vías relacionadas con la serotonina en el cerebro. Altanserina se caracteriza típicamente por su lipofilia moderada, que influye en su biodisponibilidad y distribución dentro de los sistemas biológicos. Además, se conoce por sus posibles aplicaciones en estudios de imagen, particularmente en tomografía por emisión de positrones (PET) para visualizar la actividad del receptor de serotonina. Los perfiles de seguridad y toxicidad son consideraciones esenciales en su uso, al igual que con cualquier agente farmacológico. En general, Altanserina sirve como un compuesto importante tanto en contextos terapéuticos como de investigación, ayudando en la exploración del papel de la serotonina en diversas condiciones neurológicas y psiquiátricas.

Fórmula: C₂₂H₂₂FN₃O₂S

InChI: InChI=1S/C22H22FN3O2S/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29)

Clave InChI: InChIKey=SMYALUSCZJXWHG-UHFFFAOYSA-N

SMILES: O=C1C=2C(NC(=S)N1CCN3CCC(C(=O)C4=CC=C(F)C=C4)CC3)=CC=CC2

Sinónimos:

• 278-422-1
• 3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one
• 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone
• 3-{2-[4-(4-Fluorobenzoyl)piperidin-1-yl]ethyl}-2-thioxo-2,3-dihydroquinazolin-4(1H)-one
• 4(1H)-quinazolinone, 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-
• 76330-71-7
• Altanserin
• Altanserin hydrochloride hydrate
• 3-(2-(4-(4-Fluorobenzoyl)-1-piperidinyl)ethyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinonehydrochloride
• 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone hydrate hydrochloride
• AltanserineHCl
• ALTANSERIN HYDROCHLORIDE
• 3-[2-[4-(4-FLUOROBENZOYL)-1-PIPERIDINYL]ETHYL]-2,3-DIHYDRO-2-THIOXO-4(1H)-QUINAZOLINONE HYDROCHLORIDE
• 3-[2-[4-(4-Fluorobenzoyl)piperidin-1-yl]ethyl]-2-sulfanylidene-1H-quinazolin-4-one
• Altanserin hydrate hydrochloride
• 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone hydrochloride hydrate

altanserin hydrochloride

CAS: 76330-71-7

Fórmula: C₂₂H₂₂FN₃O₂S

Pureza: 97%

Forma y color: Solid

Peso molecular: 411.4924

Ref: IN-DA0056E0

3-(2-(4-(4-Fluorobenzoyl)Piperidin-1-Yl)Ethyl)-2-Thioxo-2,3-Dihydroquinazolin-4(1H)-One

CAS: 76330-71-7

3-(2-(4-(4-Fluorobenzoyl)Piperidin-1-Yl)Ethyl)-2-Thioxo-2,3-Dihydroquinazolin-4(1H)-One

Pureza: 99%

Peso molecular: 411.49g/mol

Ref: 54-PC108570

Altanserin hydrochloride hydrate

CAS: 76330-71-7

Fórmula: C₂₂H₂₂FN₃O₂S·HCl·xH₂O

Peso molecular: 447.95 (anhydrous)

Ref: 7W-GL6252

Altanserin

CAS: 76330-71-7

Altanserin, a 5-HT2A receptor binder, is tagged with F-18 for brain PET scans.

Fórmula: C₂₂H₂₂FN₃O₂S

Forma y color: Solid

Peso molecular: 411.49

Ref: TM-T29913

Altanserin hydrochloride hydrate

CAS: 76330-71-7

Altanserin is a drug that binds to the 5-HT2 receptor and blocks its interactions with other molecules. Altanserin has been shown to have a synergic effect with antidepressants such as desipramine and fluoxetine, which are selective serotonin reuptake inhibitors (SSRIs). It has also been shown to inhibit the uptake of 5-HT in the brain, which may be related to its effect on locomotor activity. The use of altanserin for HIV infection is still being studied. One study found that altanserin reduced viral load and increased CD4+ T cell counts in HIV patients who were not taking any other anti-HIV drugs. A recent study found that altanserin at dosages up to 4mg/kg/day did not cause any toxic effects in rats.

Fórmula: C₂₂H₂₂FN₃O₂S•HCl•(H₂O)x

Pureza: Min. 95%

Ref: 3D-BA183187

Altanserin

Producto controlado

CAS: 76330-71-7

Fórmula: C₂₂H₂₂FN₃O₂S

Forma y color: Neat

Peso molecular: 411.492

Ref: TR-A585985

Altanserin

CAS: 76330-71-7

Altanserin is a drug that binds to the 5-HT2 receptor and blocks its interactions with other molecules. Altanserin has been shown to have a synergic effect with antidepressants such as desipramine and fluoxetine, which are selective serotonin reuptake inhibitors (SSRIs). It has also been shown to inhibit the uptake of 5-HT in the brain, which may be related to its effect on locomotor activity. The use of altanserin for HIV infection is still being studied. One study found that altanserin reduced viral load and increased CD4+ T cell counts in HIV patients who were not taking any other anti-HIV drugs. A recent study found that altanserin at dosages up to 4mg/kg/day did not cause any toxic effects in rats.

Pureza: Min. 95%

Ref: 3D-FA41790