CAS 76684-89-4

Ácido loxistatínico

Descripción:

Ácido loxistatínico, con el número CAS 76684-89-4, es un compuesto químico que pertenece a la clase de las estatinas, conocidas principalmente por su papel en los medicamentos para reducir el colesterol. Se caracteriza por su capacidad para inhibir la HMG-CoA reductasa, una enzima crucial en la biosíntesis del colesterol. Esta inhibición conduce a una disminución de los niveles de colesterol en el torrente sanguíneo, lo que resulta beneficioso para el manejo de la hiperlipidemia y la reducción del riesgo de enfermedades cardiovasculares. Ácido loxistatínico es típicamente un sólido blanco a blanco sucio y es soluble en disolventes orgánicos, pero su solubilidad en agua es limitada. El compuesto puede exhibir diversas actividades biológicas, incluidas propiedades antiinflamatorias y antioxidantes, que contribuyen a su potencial terapéutico. Al igual que muchas estatinas, puede tener efectos secundarios, incluidos dolor muscular y alteraciones en las enzimas hepáticas, lo que requiere monitoreo durante su uso. En general, Ácido loxistatínico representa un avance significativo en farmacología para el manejo de la salud cardiovascular.

Fórmula: C₁₅H₂₆N₂O₅

InChI: InChI=1/C15H26N2O5/c1-8(2)5-6-16-13(18)10(7-9(3)4)17-14(19)11-12(22-11)15(20)21/h8-12H,5-7H2,1-4H3,(H,16,18)(H,17,19)(H,20,21)/t10-,11-,12-/m0/s1

Clave InChI: InChIKey=SCMSYZJDIQPSDI-SRVKXCTJSA-N

SMILES: C(N[C@H](C(NCCC(C)C)=O)CC(C)C)(=O)[C@@H]1[C@@H](C(O)=O)O1

Sinónimos:

• (+)-(2S,3S)-3-((S)-3-Methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl)-2-oxiranecarboxylic acid
• (2S,3S)-3-({(2S)-4-methyl-1-[(3-methylbutyl)amino]-1-oxopentan-2-yl}carbamoyl)oxirane-2-carboxylic acid
• (2S,3S)-3-[[[(1S)-3-Methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-2-oxiranecarboxylic acid
• 2-Oxiranecarboxylic acid, 3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-, (2S,3S)-
• Brn 6688621
• E 64c
• EP 475 (Enzyme inhibitor)
• Ep 475
• Loxistatin acid
• NSC 694279
• Oxiranecarboxylic acid, 3-(((3-methyl-1-(((3-methylbutyl)amino)carbonyl)butyl)amino)carbonyl)-, (2S-(2-alpha,3-beta(R*)))-
• Oxiranecarboxylic acid, 3-(((3-methyl-1-(((3-methylbutyl)amino)carbonyl)butyl)amino)carbonyl)-, (2S-(2alpha,3beta(R*)))-
• Oxiranecarboxylic acid, 3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-, (2S,3S)-
• Oxiranecarboxylic acid, 3-[[[3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-, [2S-[2α,3β(R*)]]-
• (2S,3S)-L-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE
• (1S,2S)-2-(((S)-1-(Isopentylamino)-4-methyl-1-oxopentan-2-yl)carbamoyl)cyclopropanecarboxylic
• anecarboxylicacid
• (2S,3S)-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE
• Loxistatin Acid (E-64C)
• (2S,3S)-3-(((S)-1-(isopentylaMino)-4-Methyl-1-oxopentan-2-yl)carbaMoyl)oxirane-2-carboxylic acid
• E-64-c Loxistatin acid NSC 694279
• (L-3-TRANS-CARBOXYOXIRANE-2-CARBONYL)-L-LEUCINE (3-METHYLBUTYL)AMIDE
• (2S,3S)-3-[[(1S)-1-(3-Methylbutylcarbamoyl)-3-methylbutyl]carbamoyl]oxirane-2-carboxylic acid
• NSC 694279 Loxistatin Acid
• NSC 694279 LOXISTATIN ACID; EP 475;E64C;E 64C
• (2s-(2-alpha,3-beta(r*)))-mino)carbonyl)
• ep475(enzymeinhibitor)
• L-TRANS-EPOXYSUCCINYL-LEU-3-METHYLBUTYLAMIDE
• (+)-(2s,3s)-3-((s)-3-methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl)-2-oxir
• (2S,3S)-TRANS-EPOXYSUCCINYL-L-*LEUCYLAMI DO-3-METHYL
• oxiranecarboxylicacid,3-(((3-methyl-1-(((3-methylbutyl)amino)carbonyl)butyl)a
• Inhibitorforthiolprotease
• 2-Oxiranecarboxylicacid,3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-,(2S,3S)-
• E-64c, EP 475

E-64c

CAS: 76684-89-4

Fórmula: C₁₅H₂₆N₂O₅

Pureza: 95%

Forma y color: Solid

Peso molecular: 314.3773

Ref: IN-DA00G359

E 64c

CAS: 76684-89-4

E 64c

Pureza: ≥98%

Peso molecular: 314.38g/mol

Ref: 54-BUP02992

E-64c Calpain Inhibitor

CAS: 76684-89-4

Fórmula: C₁₅H₂₆N₂O₅

Peso molecular: 314.38

Ref: 7W-GL8757

E-64c

CAS: 76684-89-4

E-64c

Pureza: 95%

Forma y color: Solid

Peso molecular: 314.38g/mol

Ref: 54-BIE1004

E 64c

CAS: 76684-89-4

E 64c (EP 475) , a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.

Fórmula: C₁₅H₂₆N₂O₅

Pureza: 98.73%

Forma y color: Solid

Peso molecular: 314.38

Ref: TM-T6573

(2S,3S)-3-(((S)-1-(Isopentylamino)-4-methyl-1-oxopentan-2-yl)carbamoyl)oxirane-2-carboxylic acid

CAS: 76684-89-4

Pureza: ≥98%

Peso molecular: 314.3819885

Ref: 10-F869543

E-64-c

CAS: 76684-89-4

E-64-c is a research tool that is used to activate the receptor of a cell. This ligand can bind to the receptor and form a complex, which will then be able to interact with other proteins in the cell. This process can lead to changes in ion channel activity, protein synthesis, or gene expression. E-64-c has been shown to inhibit the activity of ion channels such as calcium channels and potassium channels, as well as protein synthesis. It also binds to antibodies and blocks their binding sites on cells.br>
E-64-c is a high purity ligand that can be used for studying protein interactions or pharmacological purposes. The potency of this ligand has been tested by measuring its ability to inhibit the binding of various peptides such as vasopressin and angiotensin II.

Fórmula: C₁₅H₂₆N₂O₅

Pureza: Min. 95%

Peso molecular: 314.38 g/mol

Ref: 3D-IEC-4320-V