CAS 78081-87-5

N(alpha),N(epsilon)-di-fmoc-L-lisina

Descripción:

N(alpha),N(epsilon)-di-fmoc-L-lisina es una forma protegida del aminoácido lisina, comúnmente utilizada en la síntesis de péptidos y bioconjugación. Los grupos "fmoc" (9-fluorenilmetoxicarbonilo) sirven como grupos protectores para las funcionalidades amino, permitiendo reacciones selectivas sin interferir con la reactividad de la lisina. Este compuesto presenta dos grupos fmoc, uno en el grupo amino alfa y otro en el grupo amino épsilon de la lisina, lo que mejora su estabilidad y solubilidad en disolventes orgánicos. La presencia de estos grupos protectores facilita la síntesis de péptidos al prevenir reacciones secundarias no deseadas durante el proceso de acoplamiento. Además, N(alpha),N(epsilon)-di-fmoc-L-lisina puede desprotegerse en condiciones básicas suaves, permitiendo la liberación de los grupos amino libres cuando sea necesario. Sus características estructurales contribuyen a su utilidad en el desarrollo de varios biofármacos y aplicaciones de investigación en química de péptidos. En general, este compuesto es valorado por su versatilidad y efectividad en facilitar la síntesis de estructuras peptídicas complejas.

Fórmula: C₃₆H₃₄N₂O₆

InChI: InChI=1/C36H34N2O6/c39-34(40)33(38-36(42)44-22-32-29-17-7-3-13-25(29)26-14-4-8-18-30(26)32)19-9-10-20-37-35(41)43-21-31-27-15-5-1-11-23(27)24-12-2-6-16-28(24)31/h1-8,11-18,31-33H,9-10,19-22H2,(H,37,41)(H,38,42)(H,39,40)/t33-/m0/s1

SMILES: c1ccc2c(c1)c1ccccc1C2COC(=NCCCC[C@@H](C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12)O

Sinónimos:

• Fmoc-Lys(Fmoc)-OH
• N2,N6-bis[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine
• N2,N6-Bis-Fmoc-L-lysine

Nα,Nε-Bis[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine

CAS: 78081-87-5

Fórmula: C₃₆H₃₄N₂O₆

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 590.68

Ref: 3B-B4931

Fmoc-Lys(Fmoc)-OH

CAS: 78081-87-5

Building block for the synthesis of branched peptides and MAP matrices.

Fórmula: C₃₆H₃₄N₂O₆

Pureza: 98.8%

Forma y color: White

Peso molecular: 590.68

Ref: 01-4011122

Fmoc-Lys(Fmoc)-OH

CAS: 78081-87-5

Fórmula: C₃₆H₃₄N₂O₆

Pureza: 97%

Forma y color: Solid

Peso molecular: 590.6650

Ref: IN-DA00ICX5

Fmoc-Lys(Fmoc)-OH

CAS: 78081-87-5

Fmoc-Lys(Fmoc)-OH

Pureza: 98%

Peso molecular: 590.66g/mol

Ref: 54-OR1013374

Fmoc-Lys(Fmoc)-OH

CAS: 78081-87-5

Pureza: ≥ 98.0%

Forma y color: White to faint yellow or beige powder

Peso molecular: 590.66

Ref: 7W-GM2885

Fmoc-Lys(Fmoc)-OH

CAS: 78081-87-5

Fmoc-Lys(Fmoc)-OH is an antibacterial agent that can be synthesized from a number of precursors. It has been shown to inhibit the uptake of mannose by staphylococcus cells and its subsequent use in the synthesis of bacterial cell walls. Fmoc-Lys(Fmoc)-OH also inhibits the growth of viruses, such as HIV, and human immunodeficiency virus type 1 (HIV-1), by binding to mannose receptors on the surface of macrophage-like cells. Intramolecular hydrogen bonds stabilise this complex, which prevents it from breaking down. This allows Fmoc-Lys(Fmoc)-OH to remain in the body for a longer period of time than other antibiotics that are broken down by enzymes. Fmoc-Lys(Fmoc)-OH has also been shown to be an effective antibacterial agent against Staphylococcus a

Fórmula: C₃₆H₃₄N₂O₆

Pureza: Min. 98.0 Area-%

Peso molecular: 590.67 g/mol

Ref: 3D-FLK-1750-PI

fmoc-lys(fmoc)-oh

CAS: 78081-87-5

Fórmula: C₃₆H₃₄N₂O₆

Pureza: 95%

Forma y color: Solid

Peso molecular: 590.676

Ref: 10-F045471

Fmoc-Lys(Fmoc)-OH

CAS: 78081-87-5

Fmoc-Lys(Fmoc)-OH is an ester of lysine that is used in peptide synthesis. It has shown to have antimicrobial properties against bacteria and fungi. Fmoc-Lys(Fmoc)-OH has been found to be taken up by cancer cells, suggesting that it may have anticancer effects. It has also been found to inhibit the growth of bladder cancer cells as well as histidine aminopeptidase from the cell surface. Fmoc-Lys(Fmoc)-OH is stable in trifluoroacetic acid, making it a good candidate for solid-phase synthesis. This product can be synthesized by attaching the amino acid lysine to an ester linker with a fluorinated side chain. The product is then linked end-to-end via intramolecular hydrogen bonds and chemical stability is achieved through covalent amide bond formation between Lys and Fmoc groups

Fórmula: C₃₆H₃₄N₂O₆

Pureza: Min. 95%

Forma y color: Solid

Peso molecular: 590.67 g/mol

Ref: 3D-FF28934