![1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F386020-okadaic-acid.webp&w=3840&q=75)
CAS 78111-17-8
:ácido 1,7-dioxaspiro[5.5]undec-10-eno-2-propanoico, α,5-dihidroxi-α,10-dimetil-8-[(1R,2E)-1-metil-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahidro-8'-hidroxi-6'-[(1S,3S)-1-hidroxi-3-[(2S,3R,6S)-3-metil-1,7-dioxaspiro[5.5]undec-2-il]butil]-7'-metilenespiro[furan-2(3H),2'(3'H)-pirano[3,2-b]pirano]-5-il]-2-propenil]-, (αR,2S,5R,6R,8S)-
Descripción:
ácido 1,7-dioxaspiro[5.5]undec-10-eno-2-propanoico, α,5-dihidroxi-α,10-dimetil-8-[(1R,2E)-1-metil-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahidro-8'-hidroxi-6'-[(1S,3S)-1-hidroxi-3-[(2S,3R,6S)-3-metil-1,7-dioxaspiro[5.5]undec-2-il]butil]-7'-metilenespiro[furan-2(3H),2'(3'H)-pirano[3,2-b]pirano]-5-il]-2-propenil]-, (αR,2S,5R,6R,8S)- es un compuesto orgánico complejo caracterizado por su intrincada estructura molecular, que incluye múltiples grupos funcionales como dioxaspiro, hidroxilo y moieties de ácido propanoico. Este compuesto exhibe quiralidad, indicada por sus descriptores estereoquímicos, lo que sugiere que puede existir en múltiples formas enantioméricas. Su complejidad estructural puede conferir propiedades químicas únicas, potencialmente influyendo en su reactividad e interacciones con sistemas biológicos. La presencia de múltiples anillos y centros estereogénicos sugiere que puede tener aplicaciones en farmacéuticos o como un intermedio sintético en química orgánica. Además, el número CAS del compuesto, 78111-17-8, permite una fácil identificación y referencia en bases de datos químicas. En general, esta sustancia representa un fascinante ejemplo de la síntesis orgánica moderna y la diversidad estructural en compuestos químicos.
Fórmula:C44H68O13
InChI:InChI=1/C44H68O13/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49)/b10-9+/t26-,27-,28+,30+,31+,32+,33-,34+,35-,36-,37?,38+,39?,41-,42+,43-,44-/m1/s1
Clave InChI:InChIKey=QNDVLZJODHBUFM-WFXQOWMNSA-N
SMILES:O[C@H]1[C@@]2(O[C@]([C@@H](/C=C/[C@@H]3O[C@]4(CC3)O[C@@]5([C@@](CC4)(O[C@]([C@H](C[C@H](C)[C@]6(O[C@]7(CC[C@H]6C)CCCCO7)[H])O)(C(=C)[C@H]5O)[H])[H])[H])C)(CC(C)=C2)[H])O[C@H](C[C@@](C(O)=O)(C)O)CC1
Sinónimos:- (αR,2S,5R,6R,8S)-α,5-Dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-1,7-dioxaspiro[5.5]undec-10-ene-2-propanoic acid
- 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-, (αR,2S,5R,6R,8S)-
- 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, (αR,2S,5R,6R,8S)-
- 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[1-methyl-3-[octahydro-8'-hydroxy-6'-[1-hydroxy-3-(3-methyl-1,7-dioxaspiro[5.5]undec-2-yl)butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, [2'R-[2'α[R*[1R*[2S*(R*),5R*,6R*,8S*],2E]],4'aβ,6'β[1S*,3S*(2S*,3R*,6S*)],8'α,8'aα]]-
- 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[1-methyl-3-[octahydro-8′-hydroxy-6′-[1-hydroxy-3-(3-methyl-1,7-dioxaspiro[5.5]undec-2-yl)butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, [2′R-[2′α[R*[1R*[2S*(R*),5R*,6R*,8S*],2E]],4′aβ,6′β[1S*,3S*(2S*,3R*,6S*)],8′α,8′aα]]-
- 1,7-Dioxaspiro[5.5]undecane, acanthifolicin deriv.
- 35-Demethyl-DTX 1
- 35-Demethyldinophysistoxin 1
- Acanthifolicin, 9,10-deepithio-9,10-didehydro-
- Nsc 677083
- Okadaic acid
- Spiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran], acanthifolicin deriv.
- (2R)-2-hydroxy-3-[(2S,5R,6R,8S)-5-hydroxy-8-{(2R,3E)-4-[(2R,4a'R,5R,6'S,8'R,8a'S)-8'-hydroxy-6'-{(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl}-7'-methylideneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]pyran]-5-yl]but-3-en-2-yl}-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-methylpropanoic acid
- 78111-17-8
- 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, alpha,5-dihydroxy-alpha,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4a'R,5R,6'S,8'R,8a'S)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-, (alphaR,2S,5R,6R,8S)-
- OKADAIC ACID, 25 UG*
- 9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIOFOLICIN
- Okadaic acid, free acid >98%
- Okadic acid
- OA
- OKADAIC ACID >95% PROTEIN PHOSPHATASE I
- 1,7-Dioxaspiro5.5undec-10-ene-2-propanoic acid, .alpha.,5-dihydroxy-.alpha.,10-dimethyl-8-(1R,2E)-1-methyl-3-(2R,4aR,5R,6S,8R,8aS)-octahydro-8-hydroxy-6-(1S,3S)-1-hydroxy-3-(2S,3R,6S)-3-methyl-1,7-dioxaspiro5.5undec-2-ylbutyl-7-methylenespirofuran-2(3H),2
- 9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIFOLICIN
- OKADAIC ACID FREE ACID
- Okadaic acid,97%
- OKADAICACID,HIGHPURITY
- 9,10-deepithio-9,10-didehydro-acanthifolici
- OKADAIC ACID AMMONIUM SALT WATER-SOLUBLE ANALOG
- OKADAIC ACID, 98+%
- OKADAIC ACID, PROROCENTRUM CONCAVUM
- Ocadaic Acid
- HALOCHONDRINE A
- Okadaic acid from Prorocentrum concavum,OA
- Okadaic acid 35-Demethyl-DTX 1 NSC 677083 35-Demethyldinophysistoxin 1
- OKADAIC ACID SODIUM SALT 98+%
- Blue mussel, homogenized (Okadaic acid)
- 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoicacid, a,5-dihydroxy-a,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(
- OKADAIC ACID FROM PROROCENTRUM SP.
- 9,45-Seco-10-demercapto-9,10-didehydroacanthifolicin
- Okadaicacid,Prorocentrumconcavum,highpurity
- Ver más sinónimos
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Encontrado 8 productos.
Okadaic acid, 98%
CAS:<p>Okadaic acid, is used as an activator of PKC and inhibitor of PP1 and PP2A phosphatases. The hydrophobic backbone of okadaic acid enables it to enter cells where it stimulates intracellular protein phosphorylation. It mimics the effects of insulin, enhances transmitter release at neuromuscular junct</p>Fórmula:C44H68O13Pureza:98%Forma y color:White, SolidPeso molecular:805.02Okadaic acid, Prorocentrum concavum, high purity
CAS:Fórmula:C44H68O13Pureza:>98%Peso molecular:805.015Okadaic acid
CAS:Fórmula:C44H68O13Pureza:≥ 97.0%Forma y color:White crystalline powder or solidPeso molecular:805.02Okadaic acid, free acid
CAS:Okadaic acid, free acidFórmula:C44H68O13Pureza:>98%Forma y color: white lyophilized solidPeso molecular:805.00g/molOkadaic Acid
CAS:<p>Applications Okadaic acid is a widely distributed marine toxin produced by several phytoplanktonic species and responsible for diarrheic shellfish poisoning in humans. At the molecular level, Okadaic acid is a potent and specific inhibitor of various types of serine/threonine protein phosphatases. Due to this enzymatic inhibition, Okadaic acid was reported to induce numerous alterations in relevant cellular physiological processes, including metabolic pathways such as glucose uptake, lipolysis and glycolysis, heme metabolism and glycogen and protein synthesis. OA. EU regulated marine toxin.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Valdiglesia, V., et al.: J. Toxicol. Enviro. Health., 75, 844 (2012); Kamat, P.K., et al.: Life. Sci., 90, 713 (2012); Valdiglesias, V., et al.: BMC. Genomics., 13, 46 (2012);<br></p>Fórmula:C44H68O13Forma y color:NeatPeso molecular:805.00Okadaic acid
CAS:Inhibitor of PP1 and PP2A protein phosphatasesFórmula:C44H68O13Pureza:Min. 95%Peso molecular:805 g/molOkadaic acid
CAS:<p>Okadaic acid, a polyether marine toxin, is a highly potent and selective protein phosphatase (PP) inhibitor.</p>Fórmula:C44H68O13Pureza:98%Forma y color:White Crystals Or PowderPeso molecular:805
