CAS 78628-80-5

Clorhidrato de terbinafina

Descripción:

Clorhidrato de terbinafina es un medicamento antifúngico que se utiliza principalmente para tratar infecciones por dermatofitos, como el pie de atleta, la tiña y el hongo de las uñas. Pertenece a la clase de antifúngicos llamados alilaminas y actúa inhibiendo la enzima esqualeno epoxidasa, que es crucial para la síntesis de ergosterol, un componente esencial de las membranas celulares fúngicas. Esta interrupción conduce a la muerte celular y elimina eficazmente la infección. Clorhidrato de terbinafina se administra típicamente por vía oral o tópica, dependiendo del tipo y la gravedad de la infección. La sustancia se caracteriza por su forma de polvo cristalino blanco a blanco sucio, con una solubilidad relativamente baja en agua, lo que puede afectar su absorción y biodisponibilidad. Tiene una fórmula molecular que refleja su estructura compleja, y su farmacocinética implica un extenso metabolismo hepático. Los efectos secundarios pueden incluir trastornos gastrointestinales, reacciones cutáneas y, en casos raros, toxicidad hepática. En general, Clorhidrato de terbinafina es un agente potente y ampliamente utilizado en el tratamiento de infecciones fúngicas, con un perfil de seguridad bien establecido cuando se utiliza según las indicaciones.

Fórmula: C₂₁H₂₆ClN

InChI: InChI=1/C21H25N/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19/h5-7,9-14H,16-17H2,1-4H3/b9-5+

Clave InChI: InChIKey=BWMISRWJRUSYEX-SZKNIZGXSA-N

SMILES: C(N(C/C=C/C#CC(C)(C)C)C)C=1C2=C(C=CC1)C=CC=C2.Cl

Sinónimos:

• (2E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine
• (E)-N-(6,6-Dimethyl-2-Hepten-4-Ynyl)-N-Methyl-1-Naphthalenemethylaminehydroc
• (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethanamine monohydrochloride
• (E)-N-(6,6-dimethyl-2-heptene-4-alkyne)-N-methyl-l-naphthalene methylamine hydrochloride
• 1-Naphthalenemethanamine, N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-, hydrochloride, (E)-
• 1-Naphthalenemethanamine, N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-, hydrochloride (1:1)
• 1-Naphthalenemethanamine, N-[(2E)-6,6-dimethyl-2-hepten-4-ynyl]-N-methyl-, hydrochloride
• Bramazil
• Bramizil
• Lamisil
• Lamisil Once
• Lamosil
• Muzonal
• N-(6,6-Dimethyl-2-Hepten-4-Ynyl)-N-Methyl-1-Naphthalenemethanamin(E)-1-
• N-(6,6-Dimethyl-2-Hepten-4-Ynyl)-N-Methyl-1-Naphthalenemethanamin(E)-1-Naphthalenemethanaminmon
• Naphthalenemethanaminmonohydrochloride
• Terbina
• Terbinafine HCl
• Terbinafine・HCL
• Terbine
• Terbutaline hydrochloride
• Terbinafine hydrochloride
• Terbinafine Hydrochloride
• TERNBINAFINEHCL
• N-[(2E)-6,6-DIMETHYL-2-HEPTEN-4-YNYL]-N-METHYL-1-NAPHTHALENEMETHANAMINE
• TRANS-N-(6,6-DIMETHYL-2-HEPTEN-4-YNYL)-N-METHYL-1-NAPHTHYLMETHYLAMINE HYDROCHLORIDE
• Terbinafine hdyrochloride
• Lamisil, N-[(2E)-6,6-Dimethyl-2-hepten-4-ynyl]-N-methyl-1-naphthalenemethanamine
• Trebinafine hydrochloride
• TerbutalineSulfateBase

Terbinafine

CAS: 78628-80-5, 91161-71-6

Fórmula: C₂₁H₂₅N

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 291.44

Ref: 3B-T3677

Terbinafine Hydrochloride

CAS: 78628-80-5, 91161-71-6

Fórmula: C₂₁H₂₅N·HCl

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 327.90

Ref: 3B-D2049

Terbinafine hydrochloride

CAS: 78628-80-5

Terbinafine hydrochloride

Fórmula: C₂₁H₂₅N / C₂₁H₂₆CIN

Pureza: 88.6% / 99.7%

Forma y color: White. To. Off-White

Peso molecular: 291.1987 / 431.111

Ref: 47-1159

TERBINAFINE FOR SYSTEM SUITABILITY CRS

CAS: 78628-80-5

TERBINAFINE FOR SYSTEM SUITABILITY CRS

Fórmula: C₂₁H₂₆ClN

Peso molecular: 327.8908

Ref: 41-Y0001143

TERBINAFINE HYDROCHLORIDE CRS

CAS: 78628-80-5

TERBINAFINE HYDROCHLORIDE CRS

Fórmula: C₂₁H₂₆ClN

Forma y color: White. Powder.

Peso molecular: 327.8908

Ref: 41-Y0000535

Terbinafine Hydrochloride

CAS: 78628-80-5

Aromatic monoamines and their derivatives, salts thereof, nesoi

Fórmula: C₂₁H₂₅N·HCl

Forma y color: White Powder

Peso molecular: 291.1987

Ref: 45-1643496

[(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)(naphthalen-1-ylmethyl)amine hydrochloride

CAS: 78628-80-5

Fórmula: C₂₁H₂₆ClN

Pureza: 97%

Forma y color: Solid

Peso molecular: 327.8908

Ref: IN-DA003UI5

Terbinafine hydrochloride

CAS: 78628-80-5

Terbinafine hydrochloride (KWD 2019) is a synthetic allylamine derivative structurally related to naftifine. Terbinafine is active against dermatophytes.

Fórmula: C₂₁H₂₆ClN

Pureza: 99.16% - 99.95%

Forma y color: Crystalline Powder

Peso molecular: 327.89

Ref: TM-T1411

({[(2E)-6,6-Dimethylhept-2-en-4-yn-1-yl](methyl)amino}methyl)naphthalene hydrochloride

CAS: 78628-80-5

({[(2E)-6,6-Dimethylhept-2-en-4-yn-1-yl](methyl)amino}methyl)naphthalene hydrochloride

Pureza: 98%

Peso molecular: 327.89g/mol

Ref: 54-OR13685

Terbinafine hydrochloride

CAS: 78628-80-5

Fórmula: C₂₁H₂₅N·HCl

Pureza: 99.0 - 101.0 % (dried basis)

Forma y color: White powder

Peso molecular: 327.89

Ref: 7W-GA7211

Terbinafine hydrochloride

CAS: 78628-80-5

Terbinafine hydrochloride

Pureza: ≥98%

Peso molecular: 327.89g/mol

Ref: 54-BUP16916

Terbinafine-d7 HCl

CAS: 78628-80-5

Fórmula: C₂₁H₁₈D₇N·HCl

Forma y color: White To Off-White Solid

Peso molecular: 298.48 36.46

Ref: 4Z-T-542

Terbinafine hydrochloride, EP grade

CAS: 78628-80-5

Fórmula: C₂₁H₂₅N·HCl

Pureza: ≤ 0.1%

Forma y color: White or almost white powder

Peso molecular: 327.89

Ref: 7W-GA9882

Terbinafine Hydrochloride

CAS: 78628-80-5

Forma y color: Neat

Ref: 86-MM0696.00

Terbinafine hydrochloride

CAS: 78628-80-5

Fórmula: C₂₁H₂₅N·ClH

Forma y color: Neat

Peso molecular: 327.89

Ref: 04-C17255000

Terbinafine Hydrochloride

CAS: 78628-80-5

Applications An orally active, antimycotic allylamine related to Naftifine. A specfic inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis. Antifungal.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Petranyi, G., et al.: Science, 224, 1239 (1984), Ryder, N.S., et al.: Antimicrob. Agents Chemother., 27, 252 (1985), Evans, E.G.V., et al.: Br. Med. J., 318, 1031 (1999),

Fórmula: C₂₁H₂₅N·ClH

Forma y color: Neat

Peso molecular: 327.89

Ref: TR-T107500

Terbinafine hydrochloride

CAS: 78628-80-5

Activator of the two-pore domain potassium channel TASK3

Fórmula: C₂₁H₂₆ClN

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 327.89 g/mol

Ref: 3D-FT28039

Terbinafine HCl - Bio-X ™

CAS: 78628-80-5

Terbinafine is an antifungal drug that is used in the treatment of dermatophyte infections of the toenails and fingernails. Terbinafine also treats other skin infections. This drug works by inhibiting ergosterol synthesis which in return inhibits fungal squalene monooxygenase. This results in a disruption of fungal cell wall synthesis.

Fórmula: C₂₁H₂₅N•HCl

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 327.89 g/mol

Ref: 3D-BT164461

Terbinafine hydrochloride

CAS: 78628-80-5

Fórmula: C₂₁H₂₆ClN

Pureza: 95.0%

Forma y color: Solid

Peso molecular: 327.9

Ref: 10-F332489

Terbinafine Hydrochloride

CAS: 78628-80-5

Fórmula: C₂₁H₂₅NHCl

Peso molecular: 291.4 : 36.46

Ref: ST-EA-CP-T34010