CAS 78858-44-3

(2R)-3-(hexadeciloxi)-2-metoxipropil 2-(trimetilamonio)etil fosfato

Descripción:

La sustancia química conocida como (2R)-3-(hexadeciloxi)-2-metoxipropil 2-(trimetilamonio)etil fosfato, con el número CAS 78858-44-3, es un compuesto de amonio cuaternario que exhibe propiedades anfifílicas debido a sus características duales hidrofílicas e hidrofóbicas. Este compuesto presenta un grupo hexadecil de cadena larga, que contribuye a su lipofilia, mientras que el grupo trimetilamonio proporciona una carga positiva, mejorando su solubilidad en disolventes polares. La presencia del grupo fosfato aumenta aún más su hidrofília, haciéndolo adecuado para diversas aplicaciones en campos bioquímicos y farmacéuticos, particularmente en sistemas de liberación de fármacos y como surfactante. Su configuración estructural le permite interactuar con membranas biológicas, facilitando potencialmente el transporte de moléculas a través de bicapas lipídicas. Además, este compuesto puede exhibir propiedades antimicrobianas, lo que lo hace de interés en el desarrollo de agentes antimicrobianos. En general, sus características estructurales únicas permiten una variedad de funcionalidades tanto en investigación como en aplicaciones industriales.

Fórmula: C₂₅H₅₄NO₆P

InChI: InChI=1/C25H54NO6P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-30-23-25(29-5)24-32-33(27,28)31-22-20-26(2,3)4/h25H,6-24H2,1-5H3/t25-/m1/s1

SMILES: CCCCCCCCCCCCCCCCOC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC

Sinónimos:

• ethanaminium, 2-[[[[(2R)-3-(hexadecyloxy)-2-methoxypropyl]oxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt

1-O-Hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine

CAS: 78858-44-3

1-O-Hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine is a useful scaffold, versatile building block, and useful intermediate that can be used in the synthesis of complex compounds. It is a high quality reagent and research chemical that can be used as a reaction component for speciality chemicals. 1-O-Hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine has CAS number 788584443.

Fórmula: C₂₅H₅₄NO₆P

Pureza: Min. 95 Area-%

Peso molecular: 495.67 g/mol

Ref: 3D-H-1844

1-O-Hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine

CAS: 78858-44-3

1-O-Hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine (HPC) is a phospholipid that is synthesized from the essential fatty acid linoleic acid. It has been shown to have an inhibitory effect on leukemia cells, which may be due to its ability to induce apoptosis by inducing the death of tumor cells and inhibiting protein synthesis. HPC also interacts synergistically with other agents such as phorbol esters, which can lead to increased cell death. This drug has been shown to have immunomodulatory effects in fibrosarcoma cells, where it inhibits tumor growth and induces apoptotic cell death. HPC binds to specific antigens and modulates immune responses through the inhibition of diacylglycerol production.

Fórmula: C₂₅H₅₄NO₆P

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 495.68 g/mol

Ref: 3D-FH177698

2-O-methyl PAF C-16

CAS: 78858-44-3

2-O-methyl PAF C-16 is a synthetic analog of platelet-activating factor (PAF) featuring a methyl group attached via an ether linkage at the sn-2 position. While the specific biological activities of 2-O-methyl PAF C-16 remain undercharacterized, studies with its C-18 counterpart have demonstrated its ability to modulate various biological processes. These processes include reducing plasma membrane fluidity and hindering the invasiveness of tumor cells in embryonic chick hearts. Furthermore, in rat astrocytes, the C-18 analog prompts the release of significant amounts of nitric oxide (NO) through a mechanism that involves the activation of nitric oxide synthase (NOS).

Fórmula: C₂₅H₅₄NO₆P

Forma y color: Solid

Peso molecular: 495.7

Ref: TM-T84610