CAS 79598-53-1

Ácido 6-azidohexanoico

Descripción:

Ácido 6-azidohexanoico es un compuesto orgánico caracterizado por la presencia de un grupo azido (-N3) unido a una estructura de ácido hexanoico. Este compuesto presenta una cadena de seis carbonos con un grupo funcional ácido carboxílico en un extremo y un grupo azido en el sexto carbono. Se conoce que el grupo azido es reactivo, particularmente en aplicaciones de química de clic, lo que hace que Ácido 6-azidohexanoico sea útil en bioconjugación y química de polímeros. La presencia de ambas funcionalidades, ácido carboxílico y azido, permite diversas modificaciones químicas, facilitando la síntesis de varios derivados. Además, el compuesto es típicamente un sólido a temperatura ambiente y puede exhibir solubilidad moderada en disolventes polares debido al grupo ácido carboxílico. Las consideraciones de seguridad son importantes al manejar compuestos azidos, ya que pueden ser sensibles al calor y al choque, lo que puede llevar a una descomposición explosiva. En general, Ácido 6-azidohexanoico sirve como un valioso intermedio en la química orgánica sintética y la ciencia de materiales.

Fórmula: C₆H₁₁N₃O₂

Sinónimos:

• Hexanoic acid, 6-azido-
• 6-Azidohexanoic acid
• 6-Azido-Hexanoic Acid
• 6-Azidohexanoic acid - A1945
• e-Azidocaproic acid
• 6-Azidohexanoic acid >=95%

6-Azido-hexanoic acid

CAS: 79598-53-1

Fórmula: C₆H₁₁N₃O₂

Pureza: 98%

Forma y color: Liquid

Peso molecular: 157.1704

Ref: IN-DA00G3CY

6-Azidohexanoic acid

CAS: 79598-53-1

6-Azidohexanoic acid

Pureza: 98%

Peso molecular: 157.17g/mol

Ref: 54-BICR249

6-azido-hexanoic acid

CAS: 79598-53-1

Fórmula: C6H11N3O2

Pureza: >98%

Forma y color: Liquid

Peso molecular: 157.17

Ref: 48-10-5006

6-Azidohexanoic Acid

Producto controlado

CAS: 79598-53-1

Applications 6-Azidohexanoic Acid is a reagent that is useful for click chemistry.
References Alleti, R.,et al.: J. Org. Chem., 75, 5895 (2010); Daumar, P., et al.: Bioconjug. Chem., 23, 1557 (2012)

Fórmula: C₆H₁₁N₃O₂

Forma y color: Neat

Peso molecular: 157.17

Ref: TR-A850030

6-Azido-Hexanoic Acid

CAS: 79598-53-1

6-Azido-Hexanoic Acid is a lysine derivative that is used for Click Chemistry, which involves the use of reactive nitrenes, such as azides, to create stable covalent bonds with other molecules. This product is also used in diagnostic agents and has shown anticancer activity against prostate cancer cells. 6-Azido-Hexanoic Acid can be synthesized using Click Chemistry and x-ray crystal structures have been determined. The structure consists of a cyclic peptide that contains an amide bond between two lysine residues. The compound has a neutral pH and can be detected by gravimetric analysis.

Fórmula: C₆H₁₁N₃O₂

Pureza: Min. 95%

Peso molecular: 157.17 g/mol

Ref: 3D-AHA-1904-PI

6-Azido-hexanoic acid

CAS: 79598-53-1

6-Azido-hexanoic acid is a growth factor that inhibits the binding of TGF-β to its receptor. It has been shown to inhibit the proliferation of cancer cells in vitro and in vivo. 6-Azido-hexanoic acid binds with high affinity to the acidic region of TGF-β, preventing it from binding to its receptor. This molecule also inhibits the activation of the TGF-β receptor complex by decreasing the phosphorylation of Smad 1/5/8. 6-Azido-hexanoic acid has been shown to be effective in pancreatic cancer models and control studies have demonstrated an absence of toxicity or side effects.

Fórmula: C₆H₁₁N₃O₂

Pureza: Min. 97.0 Area-%

Forma y color: Powder

Peso molecular: 157.17 g/mol

Ref: 3D-FA55794

6-Azido-hexanoic acid

CAS: 79598-53-1

Fórmula: C₆H₁₁N₃O₂

Pureza: 95%

Forma y color: Liquid

Peso molecular: 157.173

Ref: 10-F494252

6-Azidohexanoic Acid

CAS: 79598-53-1

6-Azidohexanoic acid, a six-carbon saturated fatty acid featuring an ω-terminal azide group, serves as a versatile linker for bioconjugation via copper(I)-catalyzed cycloaddition reactions (click chemistry). This functionality enables its initial acylation to a compound, forming a derivative that can subsequently be conjugated to another compound through click chemistry, facilitating the synthesis of complex molecules.

Fórmula: C₆H₁₁N₃O₂

Forma y color: Solid

Peso molecular: 157.173

Ref: TM-T84438

6-Azido-hexanoic acid

CAS: 79598-53-1

Building block for Staudinger ligation as well as for “click chemistry”. This highly selective reaction can be applied for the conjugation of peptides with various molecules and for the cyclization of peptides. The azido moiety may also be considered as a protected amino group which is deblocked under reductive conditions.

Fórmula: C₆H₁₁N₃O₂

Pureza: 99.2%

Forma y color: Colourless Oily

Peso molecular: 157.17

Ref: 01-4066756