CAS 79831-76-8

(+)-Castanospermina

Descripción:

(+)-Castanospermina es un alcaloide que se encuentra de forma natural y se deriva de las semillas del árbol australiano Castanospermum australe. Se conoce por su similitud estructural con la glucosa y se clasifica como un potente inhibidor de ciertas glicosidasas, particularmente de las α-glucosidasas. Esta característica lo hace de interés en la investigación bioquímica y en aplicaciones terapéuticas potenciales, particularmente en el contexto de infecciones virales y manejo de la diabetes. El compuesto exhibe una estereoequilibrio específico, que contribuye a su actividad biológica. (+)-Castanospermina es típicamente un sólido cristalino blanco a blanco sucio, soluble en agua y en varios disolventes orgánicos. Su fórmula molecular refleja una estructura compleja que incluye múltiples grupos hidroxilo, lo que mejora su reactividad e interacción con macromoléculas biológicas. Debido a su importancia biológica, se ha estudiado por su posible papel en la modulación de la síntesis de glicoproteínas y sus implicaciones en el desarrollo de fármacos. Sin embargo, al igual que muchos alcaloides, también puede exhibir toxicidad a concentraciones más altas, lo que requiere un manejo cuidadoso y consideraciones de dosificación en contextos de investigación y terapéuticos.

Fórmula: C₈H₁₅NO₄

InChI: InChI=1/C8H15NO4/c10-4-1-2-9-3-5(11)7(12)8(13)6(4)9/h4-8,10-13H,1-3H2/t4-,5?,6+,7+,8?/m0/s1

Clave InChI: InChIKey=JDVVGAQPNNXQDW-TVNFTVLESA-N

SMILES: O[C@@H]1[C@@]2(N(C[C@H](O)[C@H]1O)CC[C@@H]2O)[H]

Sinónimos:

• (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine
• (1S,6S,7R,8R,8aR)-Octahydro-1,6,7,8-indolizinetetrol
• (1S,6S,7R,8R,8aR)-octahydroindolizine-1,6,7,8-tetrol
• (1S,7R,8aR)-octahydroindolizine-1,6,7,8-tetrol
• 1,6,7,8-Indolizinetetrol, octahydro-, (1S,6S,7R,8R,8aR)-
• 1,6,7,8-Indolizinetetrol, octahydro-, [1S-(1α,6β,7α,8β,8aβ)]-
• Castanospermine
• Castanospermine Castanospermum australe seeds
• Castanospermine From Castanospermum*Australe Seed
• NSC 614552
• Octahydroindolizine-1,6,7,8-Tetrol
• (1S,6S,7R,8AR)-TETRAHYDROXYOCTAHYDROINDOLIZINE
• (1S,6S,7R,8R,8Ar)-Indolizidine-1,6,7,8-Tetrol /(1S,6S,7R,8R,8aR)-1,2,3,5,6,7,8,8a-Octahydroindolizine-1,6,7,8-Tetrol
• (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine 98%
• 1,6,7,8-indolizinetetrol,octahydro-,(1s-(1-alpha,6-beta,7-alpha,8-beta,8a-bet
• (8aα)-Octahydroindolizine-1β,6α,7β,8α-tetrol
• (1s,6s,7r,8r,8ar)-1,6,7,8-tetrahydroxyoctahydroindolizidine
• 1,6,7,8-TETRAHYDROXYOCTAHYDROINDOLIZINE
• (1S,6S,7R,8R,8AR)-1,6,7,8-TETRAHYDROXYOCTAHYDROINDOLIZINE
• octahydro-1,6,7,8-indolizinetetrol(1s-(1-alpha,6-beta,7-alpha,8-beta,8a-beta
• CastanosperMin
• CASTANOSPERMINE, CASTANOSPERMUM AUSTRALE
• Castanospermine, Castanospermum australe - CAS 79831-76-8 - Calbiochem
• (1S,6S,7R,8R,8aR)-Octahydroindolizine-1,6,7,8-tetraol
• [1S-(1alpha,6beta,7alpha,8beta,8alphabeta)]-Octahydro-1,6,7,8-indolizinetetrol
• (3S,4R,5R,6R,7S)-1-Azabicyclo[4.3.0]nonane-3,4,5,7-tetrol
• Castanospermine from Castanospermum austral
• 1,6,7,8-Tetrahydroxyoctahydroindolizine, Castanospermine, (1S,6S,7R,8R,8aR)-Octahydro-1,6,7,8-indolizinetetrol, (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyoctahydroindolizidine
• [1S-(1α,6β,7α,8β,8aβ)]-Octahydro-1,6,7,8-indolizinetetrol
• [1S-(1A,6B,7A,8B,8A-BETA)]-OCTAHYDRO-1,6,7,8-INDOLIZINETETROL
• Castanospermine ,98%
• (1S,6S,7R,8R,8aR)-2,3,4,5,6,7,8,8a-octahydro-1H-indolizin-4-ium-1,6,7,8-tetrol
• (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyoctahydroindolizidine, (1S,6S,7R,8R,8aR)-Octahydro-1,6,7,8-indolizinetetrol
• (1S,6S,7R,8R,8AR)-1,6,7,8-TETRAHYDROXY-&
• 7,8-indolizinetetrol,octahydro-,(1s,6s,7r,8r,8ar)-6

Castanospermine, 99%

CAS: 79831-76-8

Potent alpha and beta-glucosidase inhibitor

Fórmula: C₈H₁₅NO₄

Pureza: 99%

Peso molecular: 189.21

Ref: 02-J61071

(1S,6S,7R,8R,8aR)-octahydroindolizine-1,6,7,8-tetrol

CAS: 79831-76-8

Fórmula: C₈H₁₅NO₄

Pureza: 98%

Forma y color: Solid

Peso molecular: 189.2090

Ref: IN-DA003OPW

Castanospermine

CAS: 79831-76-8

Castanospermine

Pureza: ≥95%

Peso molecular: 189.21g/mol

Ref: 54-BUP16381

Castanospermine from Castanospermum austral

CAS: 79831-76-8

Castanospermine from Castanospermum austral

Fórmula: C₈H₁₅NO₄

Pureza: By hplc: 100% (Typical Value in Batch COA)

Forma y color: white powder

Peso molecular: 189.21g/mol

Ref: 54-BIC0126

Castanospermine

CAS: 79831-76-8

Castanospermine (1,6,7,8-Tetrahydroxyoctahydroindolizine) is a natural compound that inhibits α- and β-glucosidases, especially glucosidase l.

Fórmula: C₈H₁₅NO₄

Pureza: 99.74% - 99.93%

Forma y color: White Crystalline Solid

Peso molecular: 189.21

Ref: TM-TQ0308

Castanospermine

CAS: 79831-76-8

Fórmula: C₈H₁₅NO₄

Peso molecular: 189.21

Ref: 7W-GP5690

Castanospermine

Producto controlado

CAS: 79831-76-8

Applications Castanospermine is a plant alkaloid shown to be a potent inhibitor of lysosomal a-or beta- glucosidase. It also inhibits mammalian glucosidase 1 and beta-mannosidase from sweet almonds and fungal beta-xylosidase.
References Arch. Biochem. Biophys., 221, 593 (1983), Clin. Biochem., 17, 3 (1984), Trends Bio. Sci., 9, 32, (1984), J. Biol. Chem., 260, 15873-15879 (1985), FEBS, 1985, 28 (1986)

Fórmula: C₈H₁₅NO₄

Forma y color: Off-White

Peso molecular: 189.21

Ref: TR-C185000

Castanospermine

CAS: 79831-76-8

Plant alkaloid and inhibitor of α- and β-glucosidases. It has anti-diabetic potential since its inhibitory activity on α-glucosidases helps control the postprandial blood glucose levels and supresses hyperglycemia. The compound exhibits anti-viral activity against Dengue, Influenza, HIV and Herpes Simplex viruses thanks to its ability to interfere with folding of viral structural glycoproteins.

Fórmula: C₈H₁₅NO₄

Pureza: Min. 95 Area-%

Forma y color: White Powder

Peso molecular: 189.2 g/mol

Ref: 3D-MC08277

(1S,6S,7R,8R,8aR)-Octahydroindolizine-1,6,7,8-tetraol

CAS: 79831-76-8

Pureza: 98%

Peso molecular: 189.2109985

Ref: 10-F869935