CAS 79907-44-1

Procianidina B2 3,3′-di-O-galato

Descripción:

Procianidina B2 3,3′-di-O-galato es un compuesto polifenólico que pertenece a la familia de los flavonoides, específicamente a un tipo de proantocianidina. Se caracteriza por su estructura compleja, que incluye múltiples anillos fenólicos y grupos galoyl, lo que contribuye a sus propiedades antioxidantes. Este compuesto es conocido por su presencia en diversas fuentes vegetales, particularmente en frutas, semillas y ciertos tipos de té. Procianidina B2 3,3′-di-O-galato exhibe actividades biológicas significativas, incluyendo efectos antiinflamatorios, anticancerígenos y cardioprotectores, lo que lo hace de interés en la investigación nutricional y farmacéutica. Su solubilidad puede variar dependiendo del disolvente, y generalmente es más soluble en disolventes orgánicos que en agua. La estabilidad del compuesto puede verse influenciada por factores como el pH y la temperatura, que son consideraciones importantes tanto en la ciencia de los alimentos como en la farmacología. En general, Procianidina B2 3,3′-di-O-galato es un compuesto valioso por sus posibles beneficios para la salud y su papel en el estudio de antioxidantes naturales.

Fórmula: C₄₄H₃₄O₂₀

InChI: InChI=1/C44H34O20/c45-19-11-26(51)34-32(12-19)61-40(16-2-4-22(47)25(50)6-16)42(64-44(60)18-9-30(55)38(58)31(56)10-18)36(34)35-27(52)14-23(48)20-13-33(62-43(59)17-7-28(53)37(57)29(54)8-17)39(63-41(20)35)15-1-3-21(46)24(49)5-15/h1-12,14,33,36,39-40,42,45-58H,13H2/t33-,36-,39-,40-,42-/m1/s1

Clave InChI: InChIKey=KTLUHRSHFRODPS-RIQPQZJCSA-N

SMILES: O(C(=O)C1=CC(O)=C(O)C(O)=C1)[C@@H]2[C@H](C=3C(O[C@@H]2C4=CC(O)=C(O)C=C4)=CC(O)=CC3O)C5=C6C(C[C@@H](OC(=O)C7=CC(O)=C(O)C(O)=C7)[C@H](O6)C8=CC(O)=C(O)C=C8)=C(O)C=C5O

Sinónimos:

• (-)-Epicatechin-3-O-galloyl-(4β,8)-(-)-epicatechin-3-O-gallate
• (2R,3R)-3-O-Galloylepicatechin-4β,8-[(2R,3R)-3-O-galloylepicatechin]
• 3,3′-Digalloylprocyanidin B2
• Benzoic acid, 3,4,5-trihydroxy-, (2R,2′R,3R,3′R,4R)-2,2′-bis(3,4-dihydroxyphenyl)-3,3′,4,4′-tetrahydro-5,5′,7,7′-tetrahydroxy[4,8′-bi-2H-1-benzopyran]-3,3′-diyl ester
• Benzoic acid, 3,4,5-trihydroxy-, 2,2′-bis(3,4-dihydroxyphenyl)-3,3′,4,4′-tetrahydro-5,5′,7,7′-tetrahydroxy[4,8′-bi-2H-1-benzopyran]-3,3′-diyl ester, [2R-[2α,3α,4β(2′R*,3′R*)]]-
• Proanthocyanidin B2 3,3′-O-gallate
• Procyanidin B₂ 3,3′-di-O-gallate
• [3-O-Galloyl]-(-)-epicatechin-(4β,8)-(+)-epicatechin-3-O-gallate
• benzoic acid, 3,4,5-trihydroxy-, (2R,2'R,3R,3'R,4R)-2,2'-bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-5,5',7,7'-tetrahydroxy[4,8'-bi-2H-1-benzopyran]-3,3'-diyl ester
• Procyanidin B2 3,3′-di-O-gallate
• Benzoic acid, 3,4,5-trihydroxy-, 2,2'-bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-5,5',7,7'-tetrahydroxy[4,8'-bi-2H-1-benzopyran]-3,3'-diyl ester, [2R-[2.alpha.,3.alpha.,4.beta.(2'R*,3'R*)]]-
• Aids-082250
• (2R,2'R,3R,3'R,4R)-2,2'-bis(3,4-dihydroxyphenyl)-5,5',7,7'-tetrahydroxy-[4,8'-bichroman]-3,3'-diyl bis(3,4,5-trihydroxybenzoate)
• (2R,3R)-3-o-Galloylepicatechin-4.beta.,8-[(2R,3R)-3-o-galloylepicatechin]
• Aids082250
• [(2R,3R,4R)-2-(3,4-dihydroxyphenyl)-4-[(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyl)oxy-chroman-8-yl]-5,7-dihydroxy-chroman-3-yl] 3,4,5-trihydroxybenzoate
• Procyanidin B2 3,3'-di-O-gallate (&gt

2-[(2r,3r,4s,5r,6s)-6-[(1s)-1-[(2s,5r,7s,8r,9s)-2-[(5s)-5-[(2r,3s,4r,5r)-5-[(3s,4s,5r,6s)-6-hydroxy-4-methoxy-3,5,6-trimethyl-tetrahydropyran-2-yl]-4-methoxy-3-methyl-tetrahydrofuran-2-yl]-5-methyl-tetrahydrofuran-2-yl]-9-methoxy-2,8-dimethyl-1,6-dioxaspi

CAS: 79907-44-1

Fórmula: C₄₄H₃₄O₂₀

Pureza: 97%

Forma y color: Solid

Peso molecular: 882.7288

Ref: IN-DA0054WP

Procyanidin B2 3,3'-di-O-gallate (>80%)

Producto controlado

CAS: 79907-44-1

Applications Procyanidin B2 3,3'-di-O-gallate is an important compound whose activity results in the inhibition of growth pertaining to human prostate carcinoma cell lines. Coming from the group of compounds known as flavonoids, Procyanidin B2 3,3'-di-O-gallate shows interesting biological activities relating to various human cancer diseases.
References Saito, A. et al.: Heterocycles, 80, 1081 (2010); Shrestha, S.P. et al.: Pharm. Res., 29, 856 (2012);

Fórmula: C₄₄H₃₄O₂₀

Pureza: >80%

Forma y color: Neat

Peso molecular: 882.73

Ref: TR-P755825

Procyanidin B2 3,3'-di-o-gallate

CAS: 79907-44-1

Procyanidin B2 3,3'-di-o-gallate (PB2DOG) is a gallotannin that can be found in the leaves of the dogwood tree. It has dose-dependent effects on the serine protease activity of butanol, which is used as a model for pancreatic lipase. PB2DOG also inhibits the activity of viruses such as hepatitis C and herpes simplex virus type 1, and cancer cells such as du145 and japonica. PB2DOG has been shown to induce apoptosis in cancer cells by reducing DNA synthesis and inhibiting protein synthesis. The mechanism behind this effect is not fully understood, but it may be related to its ability to inhibit cCAAT/enhancer binding protein (C/EBP), an important transcription factor for cell proliferation.

Fórmula: C₄₄H₃₄O₂₀

Pureza: Min. 95%

Peso molecular: 882.7 g/mol

Ref: 3D-EDA90744