CAS 80-49-9
:Metobromuro de homatropina
Descripción:
Metobromuro de homatropina es un agente anticolinérgico sintético que se utiliza principalmente en oftalmología para inducir midriasis (dilatación de la pupila) y cicloplejía (parálisis del músculo ciliar). Es un compuesto de amonio cuaternario, lo que significa que lleva una carga positiva, lo que mejora su solubilidad en agua y limita su capacidad para cruzar la barrera hematoencefálica. Esta característica reduce los efectos secundarios en el sistema nervioso central en comparación con otros anticolinérgicos. La sustancia se administra típicamente como gotas para los ojos y es conocida por su inicio de acción relativamente rápido y su duración moderada del efecto. Además de sus aplicaciones oftálmicas, también puede utilizarse en otros contextos médicos donde se desean efectos anticolinérgicos. Los efectos secundarios comunes pueden incluir boca seca, visión borrosa y aumento de la presión intraocular. Debido a su perfil farmacológico específico, Metobromuro de homatropina es una herramienta valiosa tanto en entornos diagnósticos como terapéuticos en el cuidado ocular.
Fórmula:C17H24BrNO3
InChI:InChI=1/C16H21NO3/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11/h2-6,12-15,18H,7-10H2,1H3/t12-,13+,14+,15?
Clave InChI:InChIKey=FUFVKLQESJNNAN-RIMUKSHENA-M
SMILES:C[N+]1(C)[C@]2(C[C@H](OC(C(O)C3=CC=CC=C3)=O)C[C@@]1(CC2)[H])[H].[Br-]
Sinónimos:- 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropanium, 3α-hydroxy-8-methyl-, bromide, mandelate
- 1αH,5αH-Tropanium, 3α-hydroxy-8-methyl-, bromide, mandelate
- 8-Azoniabicyclo[3.2.1]octane, 3-[(2-hydroxy-2-phenylacetyl)oxy]-8,8-dimethyl-, bromide (1:1), (3-endo)-
- 8-Azoniabicyclo[3.2.1]octane, 3-[(hydroxyphenylacetyl)oxy]-8,8-dimethyl-, bromide, endo-
- 8-Methylhomatropinium bromide
- Arkitropin
- Camatropine
- Esopin
- Helbatropin
- Homapin
- Homatrocel
- Homatromide
- Homatropil
- Homatropine Methylbromide
- Homatropine methobromide
- Homatropinmethylbromid
- Homolone
- Malcotran
- Mesopin
- Methatropin
- Methatropine
- Methylbromure d'homatropine
- Methylhomatropine bromide
- Methylhomatropine hydrobromide
- Methylhomatropinium bromide
- Metilbromuro De Homatropina
- Novatrin
- Novatrine
- Novatropin
- Novatropine
- Nsc 34399
- Sed-Tems
- Sethyl
- Tropinium methobromide mandelate
- 3-{[hydroxy(phenyl)acetyl]oxy}-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane bromide
- N-methylhomatropinium bromide
- dl-homatropine methyl bromide
- 8-Azoniabicyclo[3.2.1]octane, 3-[(hydroxyphenylacetyl)oxy]-8,8-dimethyl-, bromide, (3-endo)-
- (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetate - bromomethane (1:1)
- (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetate
- Homatropine methyl bromide
- dl-methylbromide
- methylhomatropine
- 3-alpha-hydroxy-8-methyl-1-alpha-h,5-alpha-h-tropaniumbromidemandelate
- 3-((hydroxyphenylacetyl)oxy)-8,8-dimethyl-8-azoniabicyclo(3.2.1)octanbro
- endo-mid
- 8-methyl-homatropiniubromide
- Ver más sinónimos
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Encontrado 13 productos.
Homatropine Methyl Bromide
CAS:Fórmula:C17H24BrNO3Pureza:>99.0%(T)Forma y color:White to Almost white powder to crystalPeso molecular:370.29HOMATROPINE METHYLBROMIDE FOR SYSTEM SUITABILITY CRS
CAS:<p>HOMATROPINE METHYLBROMIDE FOR SYSTEM SUITABILITY CRS</p>Fórmula:C16H21NO3Forma y color:PowderPeso molecular:275.3428HOMATROPINE METHYLBROMIDE CRS
CAS:<p>HOMATROPINE METHYLBROMIDE CRS</p>Fórmula:C16H21NO3Forma y color:PowderPeso molecular:275.3428Homatropine Methylbromide
CAS:<p>Vegetable alkaloids, natural or reproduced by synthesis, their salts and other derivatives, nesoi</p>Fórmula:C17H24BrNO3Forma y color:White Colorless PowderPeso molecular:369.09396Methylhomatropine (bromide)
CAS:Fórmula:C17H24BrNO3Pureza:98%Forma y color:SolidPeso molecular:370.2814Homatropine Methylbromide
CAS:<p>Homatropine Methylbromide is the methyl bromide salt of homatropine, a synthetic tertiary amine alkaloid with antimuscarinic properties.</p>Fórmula:C17H24BrNO3Pureza:98.97%Forma y color:SolidPeso molecular:370.29Homatropine Methylbromide
CAS:Producto controladoFórmula:C17H24NO3·BrForma y color:White To Off-WhitePeso molecular:370.28Homatropine methylbromide
CAS:Producto controladoFórmula:C17H24NO3·BrForma y color:NeatPeso molecular:370.28Homatropine methyl bromide
CAS:<p>Homatropine methyl bromide is a drug that belongs to the class of anticholinergic drugs. It is used as a pharmaceutical preparation and is used in the treatment of glaucoma, diagnosis of myasthenia gravis, and as an antidote for organophosphate poisoning. Homatropine methyl bromide can be used to control diastolic pressure. This drug binds to acetylcholine receptors and increases the time needed for hydrochloric acid to break down propranolol hydrochloride. The binding constants for this drug are high, which means it has a strong affinity for acetylcholine receptors. Homatropine methyl bromide is chemically stable and does not react with fatty acids or other chemicals.</p>Fórmula:C17H24NO3·BrPureza:Min. 95%Peso molecular:370.28 g/molHomatropine Methylbromide
CAS:Producto controlado<p>Applications Homatropine methylbromide or Methylhomatropine bromide is a quaternary ammonium salt of methylhomatropine. Methylhomatropine is a peripherally acting anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system. Methylhomatropine does not cross the blood–brain barrier. Methylhomatropine is used, in addition to papaverine, as component of mild drugs that help "flush" the bile.<br>References Schroeder, F., et al.: Biochemistry, 34, 11919 (1995); Krungkrai, J., et al.: Bioorg. Med. Chem., 15, 483 (2005); Zeng, B., et al.: Microbiology, 152, 2355 (2006); Hongmanee, P., et al.: Antimicrob. Agents Chemother., 51, 1105 (2007);<br></p>Fórmula:C17H24NO3·BrForma y color:White To Off-WhitePeso molecular:370.28
