CAS 80-92-2

Pregnandiol

Descripción:

Pregnandiol es un compuesto esteroidal que sirve como un metabolito significativo de la progesterona, una hormona clave en el sistema reproductivo. Se caracteriza por su estructura química, que incluye dos grupos hidroxilo (-OH), lo que lo convierte en un diol. Pregnandiol se encuentra típicamente en forma de un líquido incoloro a amarillo pálido o sólido, dependiendo de su pureza y condiciones. Es soluble en disolventes orgánicos pero tiene una solubilidad limitada en agua. Este compuesto juega un papel crucial en varios procesos biológicos, particularmente en el metabolismo de esteroides y la regulación de funciones reproductivas. En entornos clínicos, los niveles de Pregnandiol se pueden medir para evaluar la función ovárica y monitorear el embarazo. Además, se utiliza en investigaciones para estudiar las vías hormonales y los efectos de las hormonas esteroides en el cuerpo. Debido a su importancia biológica, comprender las propiedades y el comportamiento de Pregnandiol es esencial tanto en farmacología como en endocrinología.

Fórmula: C₂₁H₃₆O₂

InChI: InChI=1/C21H36O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h13-19,22-23H,4-12H2,1-3H3/t13-,14-,15-,16-,17-,18-,19-,20+,21-/m0/s1

Clave InChI: InChIKey=YWYQTGBBEZQBGO-BERLURQNSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@H](C)O)(CC4)[H])[H])(CC[C@@]1(C[C@H](O)CC2)[H])[H])[H]

Sinónimos:

• (3alpha,5beta,20S)-pregnane-3,20-diol
• (3alpha,5beta,20alpha)-Pregnane-3,20-diol
• (3α,5β,20S)-Pregnane-3,20-diol
• 17-(1-hydroxyethyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
• 3-alpha,20-alpha-Dihydroxy-5-beta-pregnane
• 3alpha,20alpha-Dihydroxy-5beta-pregnane
• 3α,20α-Dihydroxy-5β-pregnane
• 5-beta-Pregnane, 3-alpha,20-alpha-dihydroxy-
• 5-beta-Pregnane-3-alpha, 20-alpha-diol
• 5-Β-Pregnano-3-Α-20-Α-Diol
• 5-β-Pregnan-3-α,20-α-diol
• 5beta-Pregnane, 3alpha,20alpha-dihydroxy-
• 5beta-Pregnane-3alpha,20alpha-diol (8CI)
• 5β-Pregnane-3α,20α-diol
• Brn 3083715
• Diol
• Diol (6CI,7CI)
• Nsc 1612
• Nsc 47462
• Pregnandiol
• Pregnandiol [JAN]
• Pregnane-3,20-diol
• Pregnane-3,20-diol, (3-alpha,5-beta,20S)- (9CI)
• Pregnane-3,20-diol, (3alpha,5beta,20S)- (9CI)
• Pregnane-3,20-diol, (3α,5β,20S)-
• Pregnane-3alpha,20alpha-diol
• Pregnanediol
• Unii-Jr3Jd1Y22C
• 4-06-00-06111 (Beilstein Handbook Reference)
• 5SS-PREGNANE-3ALPHA,20ALPHA-DIOL
• 5-BETA-PREGNAN-3-ALPHA, 20-ALPHA-DIOL
• (8S,9S,10S,13R,14S,17S)-17-ethyl-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,3-diol
• Pregnane-3,20-diol, (3a,5b,20S)- (9CI)
• 3a,20a-Dihydroxy-5pregnane
• THA
• 5BETA-PREGNANE-3ALPHA,20ALPHA-DIOL
• (3α,5β),20S)-
• (3a,5),20S)-Pregnane-3,20-diol
• 5b-Pregnane-3a,20a-diol (8CI)
• 5-Pregnane-3alpha,20alpha-diol
• 3-alpha,20-alpha-dihydroxy-5-beta-pregnan
• 3ALPHA,20ALPHA-Dihydroxy-5B-pregnane
• (20S)-3α,20-Dihydroxy-5β-pregnane
• (20S)-5β-Pregnan-3α,20-diol
• Pregnane-3,20-diol, (3.alpha.,5.beta.,20S)-
• 5BETA-PREGNAN-3A,20A-DIOL
• 5β-Pregnane-3α,20α-diol-d5
• 5BETA-PREGNANE-3ALPHA 20ALPHA-DIOL 98+%
• TETRAHYDRO COMPOUND ''A''

5β-Pregnane-3α,20α-diol

CAS: 80-92-2

Fórmula: C₂₁H₃₆O₂

Pureza: >98.0%(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 320.52

Ref: 3B-P0678

Pregnanediol (5β-Pregnane-3α,20(S)-diol)

CAS: 80-92-2

Forma y color: Neat

Ref: 61-FOR0222.14

5β-Pregnane-3α,20α-diol

CAS: 80-92-2

Fórmula: C₂₁H₃₆O₂

Pureza: 95%

Forma y color: Solid

Peso molecular: 320.5093

Ref: IN-DA003472

Pregnanediol

CAS: 80-92-2

Fórmula: C₂₁H₃₆O₂

Peso molecular: 320.52

Ref: 4Z-P-462005

5Β-Pregnane-3Α,20Α-Diol

CAS: 80-92-2

5Β-Pregnane-3Α,20Α-Diol

Pureza: 95%

Peso molecular: 320.52g/mol

Ref: 54-OR1023940

Pregnanediol

CAS: 80-92-2

Pregnanediol

Pureza: ≥98%

Peso molecular: 320.51g/mol

Ref: 54-BUP11432

Pregnanediol (5β-Pregnane-3α,20(S)-diol)

Producto controlado

CAS: 80-92-2

Fórmula: C₂₁H₃₆O₂

Forma y color: Neat

Peso molecular: 320.51

Ref: 86-MM0222.14

Pregnanediol

CAS: 80-92-2

Pregnanediol (5Beta-Pregnane-3Alpha,20alpha-Diol) is an inactive metabolite of progesterone by reduction at C5, C3, and C20 position.

Fórmula: C₂₁H₃₆O₂

Pureza: 98% - 99.91%

Forma y color: Solid

Peso molecular: 320.51

Ref: TM-T1688

5-β-Pregnane-3-α,20-α-diol

CAS: 80-92-2

Applications 5β-Pregnane-3α,20α-diol is a metabolite of Progesterone (P755900).
References Beall, et al.: Biochem. J., 31, 35 (1937), Okuda, A., et al.: J. Biol. Chem., 259, 7519 (1984), Russell, D., et al.: Biochemistry, 31, 4737 (1992), Kondo, K., et al.: Eur. J. Biochem., 219, 357 (1994), Westerbacka, J., et al.: J. Clin. Endocrinol. Metab., 88, 4924 (2003),

Fórmula: C₂₁H₃₆O₂

Forma y color: White To Off-White

Peso molecular: 320.51

Ref: TR-P705130

5β-Pregnane-3α,20α-diol

Producto controlado

CAS: 80-92-2

5β-Pregnane-3α,20α-diol is a human metabolite of estradiol that has been found to be an active inhibitor of the enzyme activity of GABA transaminase. It has been shown to have therapeutic potential in the prevention and treatment of cervical cancer, as well as other cancers. 5β-Pregnane-3α,20α-diol has also been found to inhibit ovarian activity. The diagnostic method for this metabolite is based on monoclonal antibody (MAb) reactivity with immunosorbent assay (ELISA) and gas chromatography/mass spectrometry (GC/MS). Women who have high values for this metabolite may be at risk for uterine cancer or breast cancer.

Fórmula: C₂₁H₃₆O₂

Pureza: Min. 98 Area-%

Forma y color: White Powder

Peso molecular: 320.51 g/mol

Ref: 3D-FP27150

5β-Pregnane-3α,20α-diol-d5

Producto controlado

CAS: 80-92-2

Applications Labelled 5β-Pregnane-3α,20α-diol, a metabolite of Progesterone (P755900).
References Beall, et al.: Biochem. J., 31, 35 (1937); Okuda, A. et al.: J. Biol. Chem., 259, 7519 (1984); Russell, D. et al.: Biochemistry, 31, 4737 (1992); Kondo, K. et al.: Eur. J. Biochem.; 219, 357 (1994); Westerbacka, J. et al.: J. Clin. Endocrinol. Metab., 88, 4924 (2003);

Fórmula: C₂₁H₃₁D₅O₂

Forma y color: Neat

Peso molecular: 325.54

Ref: TR-P705132