CAS 80307-12-6

N-succinimidil 4-maleimidobutirato

Descripción:

N-succinimidil 4-maleimidobutirato (SMBP) es un compuesto químico comúnmente utilizado en aplicaciones de bioconjugación y etiquetado de proteínas. Presenta un grupo funcional de éster succinimidilo, que es reactivo hacia grupos amina, permitiendo la formación de enlaces amida estables con proteínas u otras biomoléculas. El grupo maleimida en SMBP es particularmente significativo ya que puede reaccionar selectivamente con grupos tiol, facilitando la formación de enlaces tioéter. Esta dualidad de reactividad hace de SMBP una herramienta versátil en el campo de la bioquímica y la biología molecular, permitiendo a los investigadores crear conjugados dirigidos para diversas aplicaciones, incluyendo la entrega de fármacos, diagnósticos y el desarrollo de biosensores. SMBP se suministra típicamente como un sólido y debe manejarse con cuidado, ya que puede ser sensible a la humedad y la luz. Su estabilidad y reactividad en condiciones fisiológicas lo convierten en un reactivo valioso para estudiar interacciones y modificaciones de proteínas. Un almacenamiento y manejo adecuados son esenciales para mantener su integridad y efectividad en protocolos experimentales.

Fórmula: C₁₂H₁₂N₂O₆

InChI: InChI=1/C12H12N2O6/c15-8-3-4-9(16)13(8)7-1-2-12(19)20-14-10(17)5-6-11(14)18/h3-4H,1-2,5-7H2

SMILES: C(CC(=O)ON1C(=O)CCC1=O)CN1C(=O)C=CC1=O

N-(γ-Maleimidobutyryloxy)succinimide

CAS: 80307-12-6

A heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Useful in enzyme immunoassays This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original

Fórmula: C₁₂H₁₂N₂O₆

Peso molecular: 280.23

Ref: 02-J61850

4-Maleimidobutyric acid N-hydroxysuccinimide ester

CAS: 80307-12-6

GMBS (N-succinimidyl 4-maleimidobutyrate) is an often used heterobifunctional crosslinker, a standard reagent for conjugation of cysteine-containing peptides to carriers.

Fórmula: C₁₂H₁₂N₂O₆

Pureza: 99.3%

Forma y color: White Powder

Peso molecular: 280.24

Ref: 01-4087894

GMBS

CAS: 80307-12-6

Fórmula: C₁₂H₁₂N₂O₆

Pureza: 97%

Forma y color: Solid

Peso molecular: 280.2335

Ref: IN-DA003QT6

GMBS

CAS: 80307-12-6

GMBS is a heterobifunctional cross-linker.

Fórmula: C₁₂H₁₂N₂O₆

Forma y color: White Solid

Peso molecular: 280.23

Ref: TM-T15395

N-Maleimidobutyryloxysuccinimide ester

CAS: 80307-12-6

N-Maleimidobutyryloxysuccinimide ester

Pureza: 98%

Peso molecular: 280.23g/mol

Ref: 54-BICL226

4-Maleimidobutyric Acid N-Succinimidyl Ester

Producto controlado

CAS: 80307-12-6

Stability Hygroscopic, Moisture Sensitive
Applications A short, sulfhydryl and amino reactive heterobifunctional crosslinking reagent. Introduces maleimide groups into IgM.
References Keller, O., et al.: Helv. Chim. Acta., 58, 531 (1975), Fujiwara, K., et al.: J. Immunol. Meth., 112, 77 (1988)

Fórmula: C₁₂H₁₂N₂O₆

Forma y color: White To Light Yellow

Peso molecular: 280.23

Ref: TR-M136000

4-Maleimidobutyric acid N-succinimidyl ester

CAS: 80307-12-6

4-Maleimidobutyric acid N-succinimidyl ester is a maleimide compound that can be used as an antimicrobial. It has been shown to have the ability to bind to toll-like receptors, which are proteins found on cells that play a role in immune responses. 4-Maleimidobutyric acid N-succinimidyl ester has been shown to inhibit the growth of bacteria by binding to DNA and crosslinking it. The drug also inhibits protein synthesis and enzyme activities in bacteria. 4-Maleimidobutyric acid N-succinimidyl ester has not been tested for its effects on humans, but it has been shown to be nontoxic in animal studies. This drug may cause cell lysis and thermal expansion, which means that it may be useful in the study of axonal growth and toxicity studies.

Fórmula: C₁₂H₁₂N₂O₆

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 280.23 g/mol

Ref: 3D-FM24985

2,5-Dioxopyrrolidin-1-yl 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoate

CAS: 80307-12-6

Fórmula: C₁₂H₁₂N₂O₆

Pureza: 97%

Peso molecular: 280.236

Ref: 10-F324170

N-Succinimidyl 4-Maleimidobutyrate [Cross-linking Reagent]

CAS: 80307-12-6

Fórmula: C₁₂H₁₂N₂O₆

Pureza: >98.0%(HPLC)(N)

Forma y color: White to Light yellow to Light red powder to crystal

Peso molecular: 280.24

Ref: 3B-S0399

4-Maleimidobutyric Acid N-Hydroxysuccinimide Ester extrapure (GMBS), 99%

CAS: 80307-12-6

Fórmula: C₁₂H₁₂N₂O₆

Pureza: min.99%

Forma y color: White to light yellow to beige, Powder

Peso molecular: 280.24

Ref: SR-55114