CAS 804-30-8

Fursultiamina

Descripción:

Fursultiamina, también conocido como disulfuro de propilo de tiamina, es un derivado sintético de la tiamina (vitamina B1) que se utiliza principalmente como suplemento dietético y en el tratamiento de la deficiencia de tiamina. Se caracteriza por su capacidad para mejorar la biodisponibilidad de la tiamina, haciéndola más efectiva en el cuerpo. Fursultiamina es soluble en lípidos, lo que permite una mejor absorción en comparación con la tiamina soluble en agua. El compuesto se utiliza a menudo en formulaciones destinadas a mejorar la función neurológica y el metabolismo energético, ya que la tiamina desempeña un papel crucial en el metabolismo de los carbohidratos y la función nerviosa. Su estructura química incluye un enlace disulfuro, que contribuye a sus propiedades y eficacia únicas. Fursultiamina se considera generalmente seguro cuando se usa según las indicaciones, pero como cualquier suplemento, puede tener efectos secundarios potenciales o interacciones con otros medicamentos. Al igual que con cualquier agente terapéutico, es importante consultar a profesionales de la salud antes de usarlo, especialmente en individuos con condiciones de salud subyacentes o aquellos que toman otros medicamentos.

Fórmula: C₁₇H₂₆N₄O₃S₂

InChI: InChI=1S/C17H26N4O3S2/c1-12(16(5-6-22)26-25-10-15-4-3-7-24-15)21(11-23)9-14-8-19-13(2)20-17(14)18/h8,11,15,22H,3-7,9-10H2,1-2H3,(H2,18,19,20)

Clave InChI: InChIKey=JTLXCMOFVBXEKD-UHFFFAOYSA-N

SMILES: C(N(C(=C(SSCC1CCCO1)CCO)C)C=O)C=2C(N)=NC(C)=NC2

Sinónimos:

• Adventan
• Alinamin F
• Diteftin
• Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]-1-butenyl]-
• Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-buten-1-yl]-
• Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-butenyl]-
• Fursultiamin
• Fursultiamine
• Judolor
• Linamin
• N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]-1-butenyl]formamide
• N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-buten-1-yl]formamide
• N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-{(1Z)-4-hydroxy-1-methyl-2-[(tetrahydrofuran-2-ylmethyl)disulfanyl]but-1-en-1-yl}formamide
• N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-{5-hydroxy-3-[(tetrahydrofuran-2-ylmethyl)disulfanyl]pent-2-en-2-yl}formamide
• Retar B₁
• Tetrahydrofurfuryl thiamine disulfide
• Thiamin tetrahydrofurfuryl disulfide

Fursultiamine

CAS: 804-30-8

Fórmula: C₁₇H₂₆N₄O₃S₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 398.5433

Ref: IN-DA01CBCQ

Fursultiamine, 10mM (in DMSO)

CAS: 804-30-8

Fursultiamine, 10mM (in DMSO)

Fórmula: C₁₇H₂₆N₄O₃S₂

Pureza: ≥98%, 10 mM in DMSO

Peso molecular: 398.54

Ref: 54-BUP19966

Fursultiamine

CAS: 804-30-8

Fórmula: C₁₇H₂₆N₄O₃S₂

Pureza: ≥ 98.0%

Forma y color: White to off-white or pale yellow powder

Peso molecular: 398.54

Ref: 7W-GX9422

Fursultiamine

CAS: 804-30-8

Fursultiamine

Pureza: ≥98%

Peso molecular: 398.54g/mol

Ref: 54-BUP06909

Fursultiamine

CAS: 804-30-8

Fórmula: C₁₇H₂₆N₄O₃S₂

Pureza: >95.0%(T)(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 398.54

Ref: 3B-F1364

Fursultiamine

CAS: 804-30-8

N-((4-Amino-2-methylpyrimidin-5-yl)methyl)-N-(5-hydroxy-3-(((tetrahydrofuran-2-yl)methyl)disulfanyl)pent-2-en-2-yl)formamide

Fórmula: C₁₇H₂₆N₄O₃S₂

Pureza: 98%

Peso molecular: 398.54

Ref: IN-DG131735

Fursultiamine

CAS: 804-30-8

Fursultiamine (Alinamin F) is a disulfide derivative of thiamine, or an allithiamine. It has potential uses in the treatment of vitamin B1 deficiency.

Fórmula: C₁₇H₂₆N₄O₃S₂

Pureza: 99.86% - 99.97%

Forma y color: Solid

Peso molecular: 398.54

Ref: TM-T4552

Fursultiamine

Producto controlado

CAS: 804-30-8

Applications Fursultiamine is an oral source of thiamine, used in comparative pharmacokinectic analysis of thiamine and it’s phosphorylated metabolites administered as multivitamin preparations, identification of drug candidate against prostate cancer from aspect of somatic cell reprogramming, therapeutic tool in number of human neurological diseases.
References Park, W., et al.: Clin. Ther., 38, 2277 (2016); Kosaka, T., et al.: Cancer Sci., 104, 1017 (2013); Lonsdale, D., et al.: Med. Sci. Monit., 10, 199 (2004)

Fórmula: C₁₇H₂₆N₄O₃S₂

Forma y color: Neat

Peso molecular: 398.54

Ref: TR-F865235

Thiamine tetrahydrofurfuryl disulfide

CAS: 804-30-8

Thiamine tetrahydrofurfuryl disulfide is a thiamine derivative that has been shown to serve as a cofactor for enzymes such as peptidyl-prolyl cis-trans isomerase, which catalyzes the formation of peptide hormones. It also plays a role in the synthesis of polymers such as cellulose. Thiamine tetrahydrofurfuryl disulfide can be found in crystalline cellulose and is an important component of two-way crossover studies on peptide hormones. This drug has been shown to stimulate oxidative metabolism in cells and may have therapeutic potential for treating conditions associated with oxidative injury, such as stroke, head trauma, and heart attack.
Thiamine tetrahydrofurfuryl disulfide may also have a role in the development of inflammatory responses through its interaction with toll-like receptor 4 (TLR4).

Fórmula: C₁₇H₂₆N₄O₃S₂

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 398.55 g/mol

Ref: 3D-FT40945

FURSULTIAMINE

CAS: 804-30-8

Pureza: 98%

Peso molecular: 398.5400085

Ref: 10-F806208