CAS 80418-24-2
:Notoginsenoside R1
Descripción:
Notoginsenoside R1 es un saponina triterpenoide derivada principalmente de las raíces de Panax notoginseng, una planta conocida por sus propiedades medicinales en la medicina tradicional china. Este compuesto se caracteriza por su estructura compleja, que incluye un esqueleto similar a un esteroide con múltiples grupos hidroxilo y un moiety de azúcar, lo que contribuye a su bioactividad. Notoginsenoside R1 exhibe varios efectos farmacológicos, incluyendo propiedades antiinflamatorias, antioxidantes y neuroprotectoras. Se ha estudiado por su potencial para mejorar la función cognitiva y promover la salud cardiovascular. El compuesto es típicamente soluble en disolventes orgánicos y presenta baja solubilidad en agua, lo que puede influir en su biodisponibilidad y eficacia terapéutica. Además, Notoginsenoside R1 a menudo se investiga por su papel en la modulación de vías de señalización relacionadas con la supervivencia celular y la apoptosis, lo que lo convierte en un tema de interés en la investigación farmacológica. En general, Notoginsenoside R1 representa un componente significativo de Panax notoginseng, contribuyendo a sus beneficios para la salud y aplicaciones terapéuticas.
Fórmula:C47H80O18
InChI:InChI=1S/C47H80O18/c1-21(2)10-9-13-47(8,65-41-37(59)34(56)32(54)26(18-48)62-41)22-11-15-45(6)30(22)23(50)16-28-44(5)14-12-29(52)43(3,4)39(44)25(17-46(28,45)7)61-42-38(35(57)33(55)27(19-49)63-42)64-40-36(58)31(53)24(51)20-60-40/h10,22-42,48-59H,9,11-20H2,1-8H3/t22-,23+,24+,25-,26+,27+,28+,29-,30-,31-,32+,33+,34-,35-,36+,37+,38+,39-,40-,41-,42+,44+,45+,46+,47-/m0/s1
Clave InChI:InChIKey=LLPWNQMSUYAGQI-OOSPGMBYSA-N
SMILES:C[C@]12[C@@]3(C)[C@@]([C@@]([C@@](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)(CCC=C(C)C)C)(CC3)[H])([C@H](O)C[C@@]1([C@]5(C)[C@@]([C@@H](O[C@H]6[C@H](O[C@H]7[C@H](O)[C@@H](O)[C@H](O)CO7)[C@@H](O)[C@H](O)[C@@H](CO)O6)C2)(C(C)(C)[C@@H](O)CC5)[H])[H])[H]
Sinónimos:- (3beta,6alpha,12beta)-20-(beta-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-beta-D-xylopyranosyl-beta-D-glucopyranoside
- (3β,6α,12β)-20-(β-<span class="text-smallcaps">D</smallcap>-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-β-<smallcap>D</smallcap>-xylopyranosyl-β-<smallcap>D</span>-glucopyranoside
- (6beta,8xi,9xi,12alpha,13xi,14beta)-17-[(1S)-1-(beta-D-glucopyranosyloxy)-1,5-dimethylhex-4-en-1-yl]-3,12-dihydroxy-4,4,10,14-tetramethylgonan-6-yl 2-O-beta-D-xylopyranosyl-beta-D-glucopyranoside
- Dammarane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
- Netoginsenoside
- Notoginsenoside R 1
- Notoginsenoside R1
- Notoginsenoside R<sub>1</sub>
- Sanchinoside R<sub>1</sub>
- Sanqi glucoside R1
- beta-D-Glucopyranoside, (3beta,6alpha,12beta)-20-(beta-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-beta-D-xylopyranosyl-
- β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,6α,12β)-20-(β-<smallcap>D</smallcap>-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-β-<smallcap>D</span>-xylopyranosyl-
- (3β,6α,12β)-20-(β-D-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-β-D-xylopyranosyl-β-D-glucopyranoside
- Sanchinoside R1
- β-D-Glucopyranoside, (3β,6α,12β)-20-(β-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-β-D-xylopyranosyl-
- Ver más sinónimos
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Encontrado 12 productos.
Notoginsenoside R1
CAS:Fórmula:C47H80O18Pureza:>98.0%(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:933.14Notoginsenoside R1
CAS:Notoginsenoside R1 analytical standard provided with w/w absolute assay, to be used for quantitative titration.Fórmula:C47H80O18Pureza:(HPLC) ≥98%Forma y color:PowderPeso molecular:933.15b-D-Glucopyranoside,(3b,6a,12b)-20-(b-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-b-D-xylopyranosyl-
CAS:Fórmula:C47H80O18Pureza:98%Forma y color:SolidPeso molecular:933.1273Notoginsenoside R1
CAS:Notoginsenoside R1(NR1) is the main ingredient with cardiovascular activity in Panax notoginseng, which has some neuronal protective, antihypertensive,antioxidant, anti-inflammatory, antiapoptotic, and immune-stimulatory activities. NR1 can counteract endotoxin-induced activation of endothelial cells in vitro and endotoxin-induced lethality in mice in vivo. NR1 inhibits TNF-α-induced PAI-1 overexpression via extracellular signal-related kinases (ERK1/2) and phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling pathways, it attenuates amyloid-β-induced damage in neurons by inhibiting reactive oxygen species and modulating MAPK activation.Fórmula:C47H80O18Pureza:95%~99%Peso molecular:933.139Notoginsenoside R1
CAS:<p>Notoginsenoside R1 (Sanchinoside R1) has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties.</p>Fórmula:C47H80O18Pureza:99.57% - >99.99%Forma y color:SolidPeso molecular:933.13Notoginsenoside r1
CAS:Natural glycosideFórmula:C47H80O18Pureza:≥ 90.0 % (HPLC)Forma y color:PowderPeso molecular:933.14Notoginsenoside R1
CAS:<p>Notoginsenoside R1 is a saponin compound, which is a key bioactive ingredient derived from the roots of Panax notoginseng, a well-known traditional medicinal plant. This product is renowned for its diverse pharmacological activities, particularly its anti-inflammatory and antioxidant effects. The mode of action of Notoginsenoside R1 involves modulating various signaling pathways, including the NF-κB and MAPK pathways, which are pivotal in regulating the body's inflammatory response. Additionally, it exhibits the ability to scavenge free radicals, contributing to its antioxidative properties.</p>Fórmula:C47H80O18Pureza:Min. 95%Forma y color:White PowderPeso molecular:933.15 g/molNotoginsenoside R1
CAS:Producto controlado<p>Applications Notoginsenoside R1 acts as an anti-inflammatory agent, inhibiting TNF-α induced PAI-1 production in aortic smooth muscle cells in humans.<br>References Zhang, H. et al.: Vasc. Pharmacol., 44, 224 (2006);<br></p>Fórmula:C47H80O18Forma y color:NeatPeso molecular:933.13
