CAS 80434-86-2

(D-pro2

Descripción:

La sustancia química conocida como (D-pro2, con el número CAS 80434-86-2, es un compuesto sintético que se reconoce principalmente por su papel en la investigación y aplicaciones bioquímicas. Es un derivado de la prolina, un aminoácido que desempeña un papel crucial en la síntesis y estructura de proteínas. (D-pro2 se caracteriza por su estereoequilibrio específico, que influye en su actividad biológica e interacciones con varias enzimas y receptores. Este compuesto se utiliza a menudo en estudios relacionados con la síntesis de péptidos, el diseño de fármacos y la exploración de vías metabólicas. Su solubilidad, estabilidad y reactividad pueden variar dependiendo de las condiciones y la presencia de otras especies químicas. Al igual que muchos derivados sintéticos de aminoácidos, (D-pro2 puede exhibir propiedades únicas que lo hacen valioso en el desarrollo farmacéutico y ensayos bioquímicos. Se deben observar precauciones de seguridad y manejo, como con todas las sustancias químicas, para mitigar cualquier peligro potencial asociado con su uso.

Fórmula: C₇₄H₁₀₆N₂₀O₁₃S

InChI: InChI=1/C74H106N20O13S/c1-42(2)36-55(66(100)85-51(63(79)97)30-35-108-3)89-68(102)58(39-45-41-84-50-22-10-8-19-47(45)50)92-67(101)56(37-43-16-5-4-6-17-43)90-69(103)57(38-44-40-83-49-21-9-7-18-46(44)49)91-65(99)52(26-28-61(77)95)86-64(98)53(27-29-62(78)96)87-70(104)60-25-15-34-94(60)73(107)54(23-11-12-31-75)88-71(105)59-24-14-33-93(59)72(106)48(76)20-13-32-82-74(80)81/h4-10,16-19,21-22,40-42,48,51-60,83-84H,11-15,20,23-39,75-76H2,1-3H3,(H2,77,95)(H2,78,96)(H2,79,97)(H,85,100)(H,86,98)(H,87,104)(H,88,105)(H,89,102)(H,90,103)(H,91,99)(H,92,101)(H4,80,81,82)/t48-,51-,52?,53-,54-,55?,56-,57+,58+,59+,60-/m0/s1

Sinónimos:

• (D-Pro2,D-Trp79)-Substance P
• H-Arg-D-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Met-NH2
• (D-pro2
• [D-PRO2,D-TRP7,9]-SUBSTANCE P HYDROCHLORIDE
• 2,D-Trp7,9>-SP
• (D-Pro2,D-Trp7
• 2-Pro-7,9-Trp-substance p
• dt79
• 2-Pro-7,9-Trp-sp
• L-Arg-D-Pro-L-Lys-L-Pro-L-Gln-L-Gln-D-Trp-L-Phe-D-Trp-L-Leu-L-Met-NH2
• Substance p, 2-D-proline-7-D-tryptophan-9-D-tryptophan-
• Pttsp
• Substance P, (D-Pro2, D-Trp7,9) acetate
• L-Arg-D-Pro-L-Lys-L-Pro-L-Glu(NH2)-L-Glu(NH2)-D-Trp-L-Phe-D-Trp-L-Leu-L-Met-NH2
• ARG-D-PRO-LYS-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-MET-NH2 3HCL 6H2O
• Substance p, Pro(2)-Trp(7,9)-
• Pt-sp
• L-Methioninamide, L-arginyl-D-prolyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-D-tryptophyl-L-phenylalanyl-D-tryptophyl-L-leucyl-
• ARG-D-PRO-LYS-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-MET-NH2
• [D-PRO2,D-TRP7,9]-SUBSTANCE P 3HCL 6H2O
• substance P, prolyl(2)-tryptophan(7,9)-
• ARG-D-PRO-LYS-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-MET-NH2 HYDROCHLORIDE

[D-Pro2,D-Trp7,9]-Substance P

CAS: 80434-86-2

This product is a Substance P antagonist and is available as a 0.5mg vial. Substance P is a neuropeptide that is involved in the transmission of pain signals and inflammation. It is a member of the tachykinin neuropeptide family and is produced in the central nervous system and acts through its specific receptor neurokinin 1 receptor (NK-1R). NK-1R is present in neurons and on glial cell types. Substance P is involved in: pain perceptions as a neurotransmitter; gut motility; increased inflammation in the lungs, gastrointestinal tract and the skin and neuroinflammation. Interestingly the levels of Substance P are raised in inflammatory bowel diseases and through its involvement in cytokine release, it contributes to asthma pathology. These diverse selection of functions makes substance P a target for therapeutic research.

Fórmula: C₇₄H₁₀₆N₂₀O₁₃S

Pureza: Min. 95%

Peso molecular: 1,515.8 g/mol

Ref: 3D-PSP-4113-V

(D-Pro2,D-Trp7·9)-Substance P acetate salt

CAS: 80434-86-2

Substance P is a neuropeptide that is involved in pain perception, the cardiovascular system, and cancer. It has been shown to affect blood pressure in rats by activating the sympathetic nervous system and increasing blood vessel tone. It also has anticancer activity and may be used as a potential therapeutic agent for the treatment of cancer. Research has shown that Substance P may be an important regulator of cancer cell proliferation and metastasis. In addition, this peptide is a potent analgesic, with effects on both fast-twitch muscle tissue and slow-twitch muscle tissue. The effect on slow-twitch muscle tissue is not blocked by antagonists of the neurokinin-1 receptor (NK1R), suggesting that it may not be mediated through NK1 receptors.

Fórmula: C₇₄H₁₀₆N₂₀O₁₃S

Pureza: Min. 95%

Peso molecular: 1,515.83 g/mol

Ref: 3D-FP108553