CAS 816-94-4

1,2-Distearoil-sn-glicero-3-fosfocolina

Descripción:

1,2-Distearoil-sn-glicero-3-fosfocolina (DSPC) es un fosfolípido comúnmente utilizado en aplicaciones de bioquímica y farmacéuticas. Se caracteriza por sus dos largas cadenas de ácidos grasos saturados, específicamente ácido esteárico, que contribuyen a sus propiedades hidrofóbicas, y un grupo cabeza de fosfocolina que le confiere hidrofobicidad. Esta naturaleza anfifílica permite que el DSPC forme bicapas lipídicas, lo que lo convierte en un componente crucial en la formación de liposomas y nanopartículas lipídicas para sistemas de liberación de fármacos. El DSPC tiene una alta temperatura de transición de fase, lo que mejora la estabilidad de las formulaciones lipídicas a temperaturas fisiológicas. También es conocido por su capacidad para encapsular compuestos hidrofílicos e hidrofóbicos, lo que lo hace versátil en diversas aplicaciones, incluyendo la entrega de vacunas y la terapia génica. Además, el DSPC es biocompatible y biodegradable, lo que es esencial para su uso en formulaciones médicas y cosméticas. Su integridad estructural y funcionalidad lo convierten en una sustancia valiosa en el desarrollo de nanotransportadores y otros sistemas basados en lípidos en entornos de investigación y clínicos.

Fórmula: C₄₄H₈₈NO₈P

InChI: InChI=1/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1

Clave InChI: InChIKey=NRJAVPSFFCBXDT-HUESYALOSA-N

SMILES: [C@H](OC(CCCCCCCCCCCCCCCCC)=O)(COP(OCC[N+](C)(C)C)(=O)[O-])COC(CCCCCCCCCCCCCCCCC)=O

Sinónimos:

• (2R)-2,3-bis(octadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
• (R)-(7-Lauroyl-4-oxido-10-oxo-3,5,9-trioxa-4-phosphaheptacosyl)trimethylammonium 4-oxide
• (R)-(7-Lauroyl-4-oxido-10-oxo-3,5,9-trioxa-4-phosphaheptacosyl)trimethylammonium-4-oxid
• 1,2-<span class="text-smallcaps">L</span>-α-Distearoylphosphatidylcholine
• 1,2-Bis(stearoyl)-sn-glycero-3-phosphocholine
• 1,2-Dioctadecanoyl-sn-glycero-3-phosphocholine
• 1,2-Distearoyl-3-sn-phosphatidylcholine
• 1,2-Distearoyl-<span class="text-smallcaps">L</span>-α-glycerophosphocholine
• 1,2-Distearoyl-L-α-glycerophosphocholine
• 1,2-Distearoyl-sn-3-phosphacholine
• 1,2-Distearoyl-sn-3-phosphocholine
• 1,2-Distearoyl-sn-glycero-3-phosphatidylcholine
• 1,2-Distearoyl-sn-glycero-3-phosphocholine
• 1,2-Distearoyl-sn-glycero-3-phosphorylcholine
• 1,2-Distearoyl-sn-glycerophosphocholine
• 1,2-L-α-Distearoylphosphatidylcholine
• 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-((1-oxooctadecyl)oxy)-, hydroxide, inner salt, 4-oxide, (R)-
• 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxooctadecyl)oxy]-, inner salt, 4-oxide, (7R)-
• 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxooctadecyl)oxy]-, inner salt, 4-oxide, (R)-
• 4-Hydroxy-N,N,N-trimethyl-10-oxo-7-((1-oxooctadecyl)oxy)-3,5,9-trioxa-4-phosphaheptacosan-1-aminium hydroxide, inner salt, 4-oxide, (R)-
• 4-oxido de (R)-(7-lauroil-4-oxido-10-oxo-3,5,9-trioxa-4-fosfaheptacosil)trimetilamonio
• 4-oxyde de (R)-(7-lauroyl-4-oxydo-10-oxo-3,5,9-trioxa-4-phosphaheptacosyl)trimethylammonium
• <span class="text-smallcaps">L</span>-DSPC
• <span class="text-smallcaps">L</span>-Distearoyllecithin
• <span class="text-smallcaps">L</span>-α-Distearoylphosphatidylcholine
• <span class="text-smallcaps">L</span>-β,γ-Distearoyl-α-lecithin
• <span class="text-smallcaps">L</span>-β,γ-Distearoyl-α-phosphatidylcholine
• Choline phosphate, 3-ester with <span class="text-smallcaps">L</span>-1,2-distearin
• Choline phosphate, 3-ester with L-1,2-distearin
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-distearin, <span class="text-smallcaps">L</span>-
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-distearin, L-
• Coatsome MC 8080
• Dioctadecanoyl-<span class="text-smallcaps">L</span>-α-glycerophosphorylcholine
• Dioctadecanoyl-L-α-glycerophosphorylcholine
• Distearoyl sn-3-phosphatidylcholine
• Distearoyl-<span class="text-smallcaps">L</span>-α-glycerophosphocholine
• Distearoyl-<span class="text-smallcaps">L</span>-α-lecithin
• Distearoyl-<span class="text-smallcaps">L</span>-α-phosphatidylcholine
• Distearoyl-L-α-glycerophosphocholine
• Distearoyl-L-α-lecithin
• Distearoyl-L-α-phosphatidylcholine
• Distearoyl-sn-glycero-3-phosphocholine
• Distearoylphosphatidylcholine
• Dspc
• L-Alpha-Phosphatidylcholine, Distearoyl
• L-Distearoyllecithin
• L-beta,gamma,Disteroyl-alpha-lecithin
• L-α-Distearoylphosphatidylcholine
• L-β,γ-Distearoyl-α-lecithin
• L-β,γ-Distearoyl-α-phosphatidylcholine
• Unii-043Ipi2M0K
• [(2R)-2,3-Di(octadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
• β,γ-Distearoyl <span class="text-smallcaps">L</span>-α-phosphatidylcholine
• β,γ-Distearoyl L-α-phosphatidylcholine
• [(2R)-2,3-distearoyloxypropyl] 2-(trimethylammonio)ethyl phosphate
• L-A-PHOSPHATIDYLCHOLINE DISTEAROYL*CRYST SYNTHETIC
• L-α-Phosphatidylcholine, distearoyl
• 18:0 PC
• PC(18:0/18:0)
• (R)-2,3-Bis(stearoyloxy)propyl (2-(triMethylaMMonio)ethyl) phosphate
• propyl (2-(trimethylammonio)
• Distearoyl-L-ALPHA-phosphatidyl choline
• L-BETA,GAMMA-DISTEAROYL-ALPHA-LECITHIN
• -2,3-Bis(stearoyloxy)
• 3-sn-phosphatidylcholine, 1,2-distearoyl
• 1,2-Dioleoyl-sn-Glycero-3-Phsophocholine
• 3-sn-Phosphatidylcholine, 1,2-distearoyl, L-α-Phosphatidylcholine, distearoyl, L-β,γ-Distearoyl-α-lecithin
• L-A-PHOSPHATIDYLCHOLINE, DISTEAROYL
• L-á-Phosphatidylcholine distearoyl
• 1,2-Distearoyl-sn-glycero-3-PC
• [O-(1-O,2-O-Distearoyl-L-glycero-3-phospho)choline]anion
• DISTEAROYL LECITHIN
• 1,2-Distearoyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1,2-distearoyl, L-α-Phosphatidylcholine, distearoyl, L-β,γ-Distearoyl-α-lecithin
• L-b,g-Distearoyl-a-lecithin, DSPC

1,2-Distearoyl-sn-glycero-3-phosphocholine

CAS: 816-94-4

Fórmula: C₄₄H₈₈NO₈P

Pureza: >95.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 790.16

Ref: 3B-D3926

1,2-Distearoyl-sn-glycero-3-phosphocholine

CAS: 816-94-4

Bachem ID: 4005619.

Fórmula: C₄₄H₈₈NO₈P

Pureza: >99%

Forma y color: White

Peso molecular: 790.16

Ref: 01-4005619

1,2-Distearoyl-sn-glycero-3-phosphocholine

CAS: 816-94-4

Lecithins and other phosphoaminolipids, nesoi

Fórmula: C₄₄H₈₈NO₈P

Forma y color: White Powder

Peso molecular: 789.62476

Ref: 45-1222829

3,5,9-Trioxa-4-phosphaheptacosan-1-aminium,4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxooctadecyl)oxy]-, inner salt,4-oxide, (7R)-

CAS: 816-94-4

Fórmula: C₄₄H₈₈NO₈P

Pureza: 98%

Forma y color: Solid

Peso molecular: 790.1452

Ref: IN-DA00ID72

1,2-Distearoyl-sn-glycero-3-phosphorylcholine

CAS: 816-94-4

1,2-Distearoyl-sn-glycero-3-phosphorylcholine

Pureza: ≥98%

Peso molecular: 790.15g/mol

Ref: 54-BUP17227

1,2-Distearoyl-sn-glycero-3-phosphocholine

CAS: 816-94-4

Fórmula: C₄₄H₈₈NO₈P

Forma y color: White powder

Peso molecular: 790.15

Ref: 7W-GL9096

(R)-2,3-Bis(Stearoyloxy)Propyl (2-(TrimEthylammonio)Ethyl) Phosphate

CAS: 816-94-4

(R)-2,3-Bis(Stearoyloxy)Propyl (2-(TrimEthylammonio)Ethyl) Phosphate

Pureza: 99%

Peso molecular: 790.15g/mol

Ref: 54-OR1008465

1,2-Distearoyl-sn-Glycero-3-Phosphatidylcholine

CAS: 816-94-4

Fórmula: C44H88NO8P

Pureza: >98%

Forma y color: Solid

Peso molecular: 790.15

Ref: 48-37-1800

1,2-Distearoyl-sn-glycero-3-phosphocholine

CAS: 816-94-4

Fórmula: C₄₄H₈₈NO₈P

Pureza: 95%~99%

Peso molecular: 790.161

Ref: BP-BP2378

1,2-Distearoyl-sn-glycero-3-phosphorylcholine

CAS: 816-94-4

1,2-Distearoyl-sn-glycero-3-phosphorylcholine, a cylindrical lipid, is used to make liposomes and LNPs.

Fórmula: C₄₄H₈₈NO₈P

Pureza: 99.15% - 99.53%

Forma y color: Solid

Peso molecular: 790.15

Ref: TM-T9510

1,2-Distearoyl-sn-glycero-3-phosphocholine

CAS: 816-94-4

Fórmula: C₄₄H₈₈NO₈P

Peso molecular: 790.16

Ref: 4Z-C-5964

1,2-Distearoyl-sn-glycero-3-phosphocholine

CAS: 816-94-4

1,2-Distearoyl-sn-glycero-3-phosphocholine is an organic compound that can be used as a building block for the synthesis of more complex molecules. It has been shown to have antiplatelet properties and may be useful in the treatment of cardiovascular diseases. This chemical is also a useful intermediate for the production of pharmaceuticals or other chemicals. 1,2-Distearoyl-sn-glycero-3-phosphocholine can be obtained from natural sources and is not harmful to humans or animals when consumed.

Fórmula: C₄₄H₈₈NO₈P

Peso molecular: 790.17 g/mol

Ref: 3D-D-7850

DSPC

CAS: 816-94-4

1,2-Distearoyl-sn-glycero-3-phosphocholine (DSPC), also known as L-α-phosphatidylcholine distearoyl, is a neutral phospholipid with two saturated stearoyl chains (18:0) commonly used in the generation of artificial membranes such as lipid nanoparticles (LNP). DSPC is a formulation component for drugs as part of liposomal delivery systems, including for mRNA vaccines such as those used against COVID-19 (SARS-CoV-2).

Fórmula: C₄₄H₈₈NO₈P

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 790.15 g/mol

Ref: 3D-FP47180

(R)-2,3-BIS(STEAROYLOXY)PROPYL (2-(TRIMETHYLAMMONIO)ETHYL) PHOSPHATE

CAS: 816-94-4

Pureza: 98%

Peso molecular: 790.1610107

Ref: 10-F793317

1,2-Distearoyl-sn-glycero-3-phosphocholine

Producto controlado

CAS: 816-94-4

Fórmula: C₄₄H₈₈NO₈P

Forma y color: Neat

Peso molecular: 790.145

Ref: TR-D493600

1,2-Distearoyl-sn-glycero-3-phosphocholine-d9

Producto controlado

CAS: 816-94-4

Fórmula: C₄₄D₉H₇₉NO₈P

Forma y color: Neat

Peso molecular: 799.201

Ref: TR-D493602