CAS 82854-37-3

Equinacósido

Descripción:

Equinacósido es un compuesto fenólico derivado principalmente de la planta Echinacea, particularmente de Echinacea purpurea. Se clasifica como un glucósido, consistiendo en un grupo de ácido cafeico unido a una molécula de glucosa. Equinacósido exhibe una variedad de actividades biológicas, incluyendo efectos antioxidantes, antiinflamatorios e inmunomoduladores, que contribuyen a su uso en la medicina herbal tradicional. Se conoce que el compuesto tiene propiedades terapéuticas potenciales, particularmente en la mejora de la función inmunológica y en la lucha contra infecciones respiratorias. Equinacósido es soluble en agua y en disolventes orgánicos, lo que lo hace versátil para diversas aplicaciones en farmacéuticos y nutracéuticos. Su estabilidad y biodisponibilidad están influenciadas por factores como el pH y la temperatura. Además, la investigación continúa explorando sus mecanismos de acción y beneficios potenciales en la salud y el bienestar. Al igual que con muchos compuestos naturales, la eficacia y seguridad de Equinacósido pueden variar según la dosis y las condiciones de salud individuales, lo que requiere más estudios para comprender completamente su potencial terapéutico.

Fórmula: C₃₅H₄₆O₂₀

InChI: InChI=1/C35H46O20/c1-14-24(42)26(44)29(47)35(51-14)55-32-30(48)34(49-9-8-16-3-6-18(38)20(40)11-16)53-22(13-50-33-28(46)27(45)25(43)21(12-36)52-33)31(32)54-23(41)7-4-15-2-5-17(37)19(39)10-15/h2-7,10-11,14,21-22,24-40,42-48H,8-9,12-13H2,1H3/b7-4+/t14-,21+,22+,24-,25+,26+,27-,28+,29+,30+,31+,32+,33+,34+,35-/m0/s1

Clave InChI: InChIKey=FSBUXLDOLNLABB-WZJPPVJYSA-N

SMILES: O(C(C=CC1=CC(O)=C(O)C=C1)=O)[C@H]2[C@H](O[C@H]3[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O3)[C@@H](O)[C@H](OCCC4=CC(O)=C(O)C=C4)O[C@@H]2CO[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O

Sinónimos:

• (2E)-3-(3,4-Dihydroxyphényl)acrylate de (2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphényl)éthoxy]-5-hydroxy-2-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran-2-yl]oxy}méthyl)-4-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-méthyltétrahydro-2H-pyran-2-yl]oxy}tétrahydro-2H-pyran-3-yle
• (2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}methyl)-4-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}tetrahydro-2H-pyran-3-yl (2E)-3-(3,4-dihydroxyphenyl)acrylate
• (2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}methyl)-4-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}tetrahydro-2H-pyran-3-yl-(2E)-3-(3,4-dihydroxyphenyl)acrylat
• 2-(3,4-Dihydroxyphenyl)ethyl 6-deoxy-alpha-L-mannopyranosyl-(1-> 3)-[beta-D-glucopyranosyl-(1-> 6)]-4-O-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]-beta-D-glucopyranoside
• 2-(3,4-Dihydroxyphenyl)ethyl 6-deoxy-alpha-L-mannopyranosyl-(1-> 3)-[beta-D-glucopyranosyl-(1-> 6)]-4-O-[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]-beta-D-glucopyranoside
• 6-Désoxy-alpha-L-mannopyranosyl-(1-> 3)-[bêta-D-glucopyranosyl-(1-> 6)]-4-O-[(2E)-3-(3,4-dihydroxyphényl)-2-propènan-1-oyl]-bêta-D-glucopyranoside de 2-(3,4-dihydroxyphényl)éthyle
• beta-D-glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-alpha-L-mannopyranosyl-(1-> 3)-O-[beta-D-glucopyranosyl-(1-> 6)]-4-O-[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]-
• beta-D-glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-alpha-L-mannopyranosyl-(1-> 3)-O-[beta-D-glucopyranosyl-(1-> 6)]-4-O-[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]-
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→3)-O-[β-<smallcap>D</span>-glucopyranosyl-(1→6)]-, 4-[3-(3,4-dihydroxyphenyl)-2-propenoate]
• Echinacoside
• β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-α-L-mannopyranosyl-(1→3)-O-[β-D-glucopyranosyl-(1→6)]-, 4-[3-(3,4-dihydroxyphenyl)-2-propenoate]
• (1-3)-o-(beta-d-glucopyranosyl-(1-6))-,4-(3-(3,4-dihydroxyphenyl)-2-propenoat
• Echicoside
• [(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)
• ECHINACOSIDE 20% DESERTLIVING CISTANCHE P.E.
• Echinacoside, froM Cistanche deserticola Y.C.Ma
• Echinacoside/CH54339
• [(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
• beta-d-e
• Cistanche tubulosa
• Echinacoside Standard
• ECHINACOSIDE(AHP)
• ECHINACOSIDE(AMERICAN HERBAL PHARMACOPOEIA)
• 2-(3,4-dihydroxyphenyl)ethylo-6-deoxy-alpha-l-mannopyranosyl-glucopyranosid
• Echinacoside, 98%, from Cistanche deserticola Y.C.Ma
• 2-(3,4-Dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-6-O-β-D-glucopyranosyl-4-O-[3-(3,4-dihydroxyphenyl)propenoyl]-β-D-glucopyranoside
• Purpureaside C
• ECHINACOSIDE WITH HPLC

Echinacoside

CAS: 82854-37-3

Echinacoside analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₃₅H₄₆O₂₀

Pureza: (HPLC) ≥98%

Forma y color: Powder

Peso molecular: 786.74

Ref: 11-4988S

Echinacoside

CAS: 82854-37-3

Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives

Fórmula: C₃₅H₄₆O₂₀

Forma y color: Off-White Powder

Peso molecular: 786.25824

Ref: 45-1231750

Echinacoside

CAS: 82854-37-3

Fórmula: C₃₅H₄₆O₂₀

Pureza: %

Forma y color: Solid

Peso molecular: 786.7277

Ref: IN-DA00G2TM

Echinacoside

CAS: 82854-37-3

Echinacoside

Pureza: 98%

Peso molecular: 786.73g/mol

Ref: 54-OR1024253

Echinacoside

CAS: 82854-37-3

Echinacoside

Pureza: ≥98%

Peso molecular: 786.73g/mol

Ref: 54-BUP00152

Echinacoside

CAS: 82854-37-3

Fórmula: C₃₅H₄₆O₂₀

Pureza: ≥ 98.0%

Forma y color: White off-white or beige powder

Peso molecular: 786.73

Ref: 7W-GL0233

Echinacoside

CAS: 82854-37-3

Echinacoside is a natural polyphenolic compound, has various kinds of pharmacological activities, such as anti-senescence, anti-hypoxia, anti-cancer, anti-osteoporosis, antioxidative, anti-inflammatory, neuroprotective, hepatoprotective, nitric oxide radical-scavenging and vasodilative ones. Echinacoside can improve the hematopoietic function of bone marrow in 5-FU-induced myelosuppression mice, it induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1. Echinacoside inhibits cytochrome c release and caspase-3 activation caused by ensuing rotenone exposure via activating Trk-extracellular signal-regulated kinase (ERK) pathway in neuronal cells.

Fórmula: C₃₅H₄₆O₂₀

Pureza: 95%~99%

Peso molecular: 786.733

Ref: BP-BP0520

Echinacoside

CAS: 82854-37-3

Echinacoside: a polyphenol with anti-inflammatory, antioxidant, liver and nerve protection, NO scavenging, and vasodilation properties.

Fórmula: C₃₅H₄₆O₂₀

Pureza: 99.59% - >99.99%

Forma y color: White Crystal

Peso molecular: 786.73

Ref: TM-T1716

Echinacoside

CAS: 82854-37-3

Natural glycoside

Fórmula: C₃₅H₄₆O₂₀

Pureza: ≥ 95.0 % (HPLC)

Forma y color: Powder

Peso molecular: 786.74

Ref: 5G-89188

Echinacoside Ethanolate

CAS: 82854-37-3

Applications Echinacoside Ethanolate is a caffeic acid glycoside, known for its neuroprotective, antiinflammatory and anti-oxidative activities. Also an anti[proliferative towards hypoxia influenced pulmonary artery smooth muscle cells.
References Gai, X. et al.: J. Pharm. Sci., 126, 155 (2014);

Fórmula: C₃₅H₄₆O₂₀

Forma y color: Neat

Peso molecular: 786.73

Ref: TR-E325620

Echinacoside

CAS: 82854-37-3

Echinacoside is a caffeic acid derivative naturally found in plants, such as, Echinacea angustifolia DC. Echinacoside belongs to the class of phenylethanoid glycosides. In vitro studies have revealed the mode of action of echinacoside in breast cancer cells; echinacoside suppresses the Wnt/β-catenin signalling pathway exerting anticancer activity (Tang et al, 2020). Echinacoside has been reported as beneficial for human health in terms of neuroprotection, cardioprotectiony, anti-inflammatory, antioxidant and anti-osteoporotic activity (Liu, 2018).

Fórmula: C₃₅H₄₆O₂₀

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 786.74 g/mol

Ref: 3D-OE08287