CAS 828934-41-4

Ácido 2-oxiranecarboxílico, 2-[6-(4-clorofenoxi)hexil]-, sal de sodio (1:1), (2R)-

Descripción:

Ácido 2-oxiranecarboxílico, 2-[6-(4-clorofenoxi)hexil]-, sal de sodio (1:1), (2R)- es un compuesto químico caracterizado por su estructura única que incluye un grupo epóxido (oxirano) y un grupo funcional ácido carboxílico. La presencia de la sal de sodio indica que el compuesto es probablemente soluble en agua, lo que puede aumentar su utilidad en diversas aplicaciones, como en productos farmacéuticos o agroquímicos. El grupo 4-clorofenoxilo contribuye a sus características hidrofóbicas, lo que puede influir en su actividad biológica e interacción con otras moléculas. La estereoquímica del compuesto, indicada por la designación (2R), sugiere arreglos espaciales específicos que pueden afectar su reactividad e interacciones en sistemas biológicos. En general, este compuesto puede exhibir propiedades interesantes debido a su combinación de grupos funcionales, lo que lo convierte en un tema de interés para futuras investigaciones en campos como la química medicinal o la ciencia de materiales.

Fórmula: C₁₅H₁₉ClO₄·Na

InChI: InChI=1S/C15H19ClO4.Na/c16-12-5-7-13(8-6-12)19-10-4-2-1-3-9-15(11-20-15)14(17)18;/h5-8H,1-4,9-11H2,(H,17,18);/t15-;/m1./s1

Clave InChI: InChIKey=ZUMIFLJZQDMWAU-XFULWGLBSA-N

SMILES: C(CCCCCOC1=CC=C(Cl)C=C1)[C@]2(C(O)=O)CO2.[Na]

Sinónimos:

• (+)-Etomoxir Sodium Hydrate
• (+)-Etomoxir hydrate sodium salt
• 2-Oxiranecarboxylic acid, 2-[6-(4-chlorophenoxy)hexyl]-, sodium salt (1:1), (2R)-
• Anti-eapii (ttrap)
• Oxiranecarboxylic acid, 2-[6-(4-chlorophenoxy)hexyl]-, sodium salt, (2R)-
• R(+)-2-[6-(4-Chlorophenoxy)Hexyl]-Oxirane-2-Carboxylic Acid Sodium Salt Hydrate
• R(+)-2-[6-(4-Chlorophenoxy)hexyl]-oxirane-2-carboxylic
• sodium (2R)-2-[6-(4-chlorophenoxy)hexyl]oxirane-2-carboxylate hydrate

Etomoxir sodium salt

CAS: 828934-41-4

Etomoxir sodium salt

Pureza: ≥98%

Peso molecular: 320.74g/mol

Ref: 54-BUP10353

(R)-(+)-Etomoxir sodium

CAS: 828934-41-4

(R)-(+)-Etomoxir sodium

Pureza: 98%

Peso molecular: 320.74g/mol

Ref: 54-BISN0105

Etomoxir Impurity 1 Sodium Salt

CAS: 828934-41-4

Fórmula: C₁₅H₁₈ClO₄·Na

Peso molecular: 297.76 22.99

Ref: 4Z-E-232004

(+)-Etomoxir sodium salt hydrate

CAS: 828934-41-4

Fórmula: C₁₅H₁₈ClO₄·Na·H₂O

Pureza: (HPLC) ≥ 98.0%

Forma y color: White powder

Peso molecular: 338.76

Ref: 7W-GL0593

Etomoxir Impurity 1-13C6 Sodium Salt

CAS: 828934-41-4

Fórmula: C₉₁₃C₆H₁₈ClO₄·Na

Peso molecular: 303.71

Ref: 4Z-E-232005

Etomoxir sodium salt

CAS: 828934-41-4

Etomoxir sodium salt ((R)-Etomoxir sodium salt) is a carnitine palmitoyltransferase 1a (CPT-1a) inhibitor that blocks fatty acid synthesis.

Fórmula: C₁₅H₁₈ClO₄·Na

Pureza: 99.34% - 99.82%

Forma y color: Solid

Peso molecular: 320.74

Ref: TM-T4535

Sodium (R)-2-(6-(4-chlorophenoxy)hexyl)oxirane-2-carboxylate

CAS: 828934-41-4

Fórmula: C₁₅H₁₈ClNaO₄

Pureza: 98%

Forma y color: Liquid, No data available.

Peso molecular: 320.74

Ref: 10-F516300

(2R)-2-[6-(4-Chlorophenoxy)hexyl]-oxiranecarboxylic Acid Sodium Salt

Producto controlado

CAS: 828934-41-4

Applications (2R)-2-[6-(4-Chlorophenoxy)hexyl]-oxiranecarboxylic Acid Sodium Salt is a carnitine palmatoyltransferase 1 inhibitor. It is also a chemo-sensitizing agent that is able to induce apoptosis in HL60 cells when used with glycolytic inhibitors such as 2-deoxy-D-glucose (D239000) and lonidamine (L469458).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Estan, M. C., et al.: PLoS One. 9, e115250 (2014); Li, A. J., et al.: Am J Physiol Regul Integr Comp Physiol. 310, R724 (2016)

Fórmula: C₁₅H₁₈ClO₄·Na

Forma y color: White To Off-White

Peso molecular: 320.744

Ref: TR-C433080

(2R)-2-[6-(4-Chlorophenoxy)hexyl]-2-oxiranecarboxylic acid sodium

CAS: 828934-41-4

(+)-Etomoxir sodium salt hydrate is a chemical compound classified as a carnitine palmitoyltransferase 1 (CPT1) inhibitor, which is a compound derived synthetically. Its mode of action involves the inhibition of the enzyme CPT1, which is pivotal in the transport of long-chain fatty acids into the mitochondria for β-oxidation. This inhibition effectively blocks fatty acid oxidation pathways, leading to alterations in metabolic states.Etomoxir is commonly utilized in scientific research to study metabolic processes, particularly those related to energy metabolism and metabolic disorders. It serves as a valuable tool in exploring mechanisms involved in diabetes, obesity, and cardiovascular diseases by allowing researchers to scrutinize the metabolic adaptations to impaired fatty acid oxidation. Furthermore, it is used in cellular and animal models to investigate metabolic inflexibility and mitochondrial function. Its application extends to cancer research, where metabolic reprogramming is a focus, aiding in the understanding of tumor progression and potential therapeutic interventions targeting metabolic pathways.

Fórmula: C₁₅H₁₈ClNaO₄

Peso molecular: 320.74 g/mol

Ref: 3D-BE164435