CAS 83002-04-4

5-(1,1-Dimetilheptil)-2-[(1R,2R,5R)-5-hidroxi-2-(3-hidroxipropil)ciclohexil]fenol

Descripción:

La sustancia química conocida como 5-(1,1-Dimetilheptil)-2-[(1R,2R,5R)-5-hidroxi-2-(3-hidroxipropil)ciclohexil]fenol, con el número CAS 83002-04-4, es un compuesto sintético reconocido principalmente por su aplicación en el campo de la investigación de cannabinoides. Este compuesto presenta una estructura molecular compleja que incluye un grupo fenólico y un moiety de ciclohexilo, que contribuyen a su potencial actividad biológica. Se caracteriza por su naturaleza hidrofóbica debido a la presencia de largas cadenas alquílicas, lo que puede influir en su solubilidad e interacción con membranas biológicas. La estereoquímica indicada por la configuración (1R,2R,5R) sugiere arreglos espaciales específicos que pueden afectar las propiedades farmacológicas del compuesto. Como un análogo de cannabinoide, puede interactuar con los receptores de cannabinoides en el cuerpo, influyendo potencialmente en varios procesos fisiológicos. Sin embargo, se necesitan estudios detallados para comprender completamente su eficacia, seguridad y posibles aplicaciones terapéuticas.

Fórmula: C₂₄H₄₀O₃

InChI: InChI=1S/C24H40O3/c1-4-5-6-7-14-24(2,3)19-11-13-21(23(27)16-19)22-17-20(26)12-10-18(22)9-8-15-25/h11,13,16,18,20,22,25-27H,4-10,12,14-15,17H2,1-3H3/t18-,20-,22-/m1/s1

Clave InChI: InChIKey=YNZFFALZMRAPHQ-SYYKKAFVSA-N

SMILES: C(CCO)[C@H]1[C@@H](C[C@H](O)CC1)C2=C(O)C=C(C(CCCCCC)(C)C)C=C2

Sinónimos:

• (-)-Cp 55940
• 2-[(1S,2R,5S)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol
• 5-(1,1-Dimethylheptyl)-2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol
• 5-(1,1-dimethylheptyl)-2-[(1S,2R,5S)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol
• Phenol, 5-(1,1-dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-, (1α,2β,5α)-(-)-
• phenol, 5-(1,1-dimethylheptyl)-2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-
• phenol, 5-(1,1-dimethylheptyl)-2-[(1S,2R,5S)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-

CP-55940

CAS: 83002-04-4

Fórmula: C₂₄H₄₀O₃

Peso molecular: 376.57

Ref: 7W-GL0738

(-)-CP 55,940 (10 mg/mL in methanol)

Producto controlado

CAS: 83002-04-4

Applications CP 55,940 is a cannabinoid agonist which is considerably more potent than Δ9-THC in both behavioral tests and receptor binding assays. Displays high and roughly equal affinity for both central and peripheral cannabinoid receptors (Ki = 0.6 - 5.0 and 0.7 - 2.6 nM at CB1 and CB2 respectively; EC50 values are 0.2, 0.3 and 5 nM at CB1, CB2 and GRP55 respectively).Controlled substance. Synthetic Cannabinoids
References Wiley, et al.: Neuropharmacology, 34, 669 (1995); Griffin, et al.: J. Pharmacol. Exp. Ther., 285, 553 (1998); Thomas, et al.: J. Pharmacol. Exp. Ther., 285, 285 (1998); Ryberg, et al.: Br. J. Pharmacol., 152, 1092 (2007);

Fórmula: C₂₄H₄₀O₃

Forma y color: Single Solution

Peso molecular: 376.57

Ref: TR-C781410

CP 55940

Producto controlado

CAS: 83002-04-4

CP 55940 is a cannabinoid receptor agonist that inhibits acetylcholine release in the brain and has been shown to cause neuronal death. CP 55940 binds to the α7 nicotinic acetylcholine receptor, which is important for memory and learning. The binding of this drug causes an increase in guanine nucleotide-binding protein (G protein) activity by reducing the rate of GTP hydrolysis, leading to inhibition of adenylyl cyclase activity and subsequent decrease in cAMP levels. CP 55940 has significant up-regulation of toll-like receptors following exposure, which leads to an increased immune response. This drug can also cause bowel disease or side effects such as seizures and psychotic symptoms. CP 55940 can interact with other drugs, including cannabinoids that may lead to serious side effects.

Fórmula: C₂₄H₄₀O₃

Pureza: Min. 95%

Peso molecular: 376.57 g/mol

Ref: 3D-FD146910