CAS 84-36-6

Sirocingopina

Descripción:

Sirocingopina es un compuesto orgánico clasificado como un alcaloide, derivado principalmente de la especie vegetal *Sirocingopina* y plantas relacionadas. Es conocido por su complejidad estructural, que presenta un marco bicíclico que incluye un anillo de piperidina. El compuesto exhibe una variedad de actividades biológicas, incluyendo posibles efectos analgésicos y antihipertensivos, lo que lo hace de interés en la investigación farmacológica. Sirocingopina se caracteriza típicamente por su solubilidad en disolventes orgánicos, mientras que su solubilidad en agua es limitada. El compuesto tiene un peso molecular relativamente bajo y a menudo se estudia por sus interacciones con varios objetivos biológicos, incluidos receptores y enzimas. Sus propiedades químicas, como el punto de fusión y el punto de ebullición, están influenciadas por su estructura molecular y grupos funcionales. Al igual que muchos alcaloides, Sirocingopina también puede exhibir propiedades quirales, lo que lleva a diferentes actividades biológicas dependiendo de su estereoquímica. En general, Sirocingopina representa un área significativa de estudio en química medicinal e investigación de productos naturales.

Fórmula: C₃₅H₄₂N₂O₁₁

InChI: InChI=1S/C35H42N2O11/c1-7-46-35(40)48-31-26(42-3)12-18(13-27(31)43-4)33(38)47-28-14-19-17-37-11-10-22-21-9-8-20(41-2)15-24(21)36-30(22)25(37)16-23(19)29(32(28)44-5)34(39)45-6/h8-9,12-13,15,19,23,25,28-29,32,36H,7,10-11,14,16-17H2,1-6H3/t19-,23+,25-,28-,29+,32+/m1/s1

Clave InChI: InChIKey=ZCDNRPPFBQDQHR-SSYATKPKSA-N

SMILES: C(OC)(=O)[C@H]1[C@]2(C[C@@]3(C4=C(C=5C(N4)=CC(OC)=CC5)CCN3C[C@]2(C[C@@H](OC(=O)C6=CC(OC)=C(OC(OCC)=O)C(OC)=C6)[C@@H]1OC)[H])[H])[H]

Sinónimos:

• (1S,2R,3R,4aS,13bR,14aS)-3-({4-[(éthoxycarbonyl)oxy]-3,5-diméthoxybenzoyl}oxy)-2,11-diméthoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodécahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoléine-1-carboxylate de méthyle
• (3Bêta,16Bêta,17Alpha,18Bêta,20Alpha)-18-({4-[(Éthoxycarbonyl)Oxy]-3,5-Diméthoxybenzoyl}Oxy)-11,17-Diméthoxyyohimban-16-Carboxylate De Méthyle
• (3b,16b,17a,18b,20a)-18-[[4-[(Ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl]oxy]-11,17-dimethoxyyohimban-16-carboxylic Acid Methyl Ester
• 3β,20α-Yohimban-16β-carboxylic acid, 18β-hydroxy-11,17α-dimethoxy-, methyl ester, 4-hydroxy-3,5-dimethoxybenzoate (ester) ethyl carbonate (ester)
• Carbethoxysyringoyl Methyl Reserpate
• Carbethoxysyringoyl methylreserpate
• Hf 41T
• Isotense
• Londomin
• Methyl (1S,2R,3R,4aS,13bR,14aS)-3-({4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl}oxy)-2,11-dimethoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate
• Methyl (3Beta,16Beta,17Alpha,18Beta,20Alpha)-18-({[4-{[(Ethyloxy)Carbonyl]Oxy}-3,5-Bis(Methyloxy)Phenyl]Carbonyl}Oxy)-11,17-Bis(Methyloxy)Yohimban-16-Carboxylate
• Methyl (3Beta,16Beta,17Alpha,18Beta,20Alpha)-18-[({4-[(Ethoxycarbonyl)Oxy]-3,5-Dimethoxyphenyl}Carbonyl)Oxy]-11,17-Dimethoxyyohimban-16-Carboxylate
• Methyl (3beta,16beta,17alpha,18beta,20alpha)-18-({4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl}oxy)-11,17-dimethoxyyohimban-16-carboxylate
• Methyl carbethoxysyringoyl reserpate
• Methyl reserpate ester of syringic acid ethyl carbonate
• Methyl-(1S,2R,3R,4aS,13bR,14aS)-3-({4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl}oxy)-2,11-dimethoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isochinolin-1-carboxylat
• NSC 77030
• Raunova
• Reserpic acid, methyl ester, ester with syringic acid, ethyl carbonate
• Seniramin
• Singoserp
• Siringina
• Sml 1908
• Su 3118
• Syringic acid ethyl carbonate ester with methyl reserpate
• Syringopine
• Syrosingopin

Syrosingopine

CAS: 84-36-6

Syrosingopine analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Fórmula: C₃₅H₄₂N₂O₁₁

Pureza: (HPLC) ≥90%

Forma y color: Powder

Peso molecular: 666.73

Ref: 11-1691

Syrosingopine

CAS: 84-36-6

Syrosingopine

Pureza: ≥98%

Peso molecular: 666.71g/mol

Ref: 54-BUP07583

Syrosingopine

CAS: 84-36-6

Syrosingopine is a dual inhibitor of MCT1 and MCT4, 60 times more potent against MCT4, preventing lactate and H+ efflux.Cost-effective and quality-assured.

Fórmula: C₃₅H₄₂N₂O₁₁

Pureza: 99.25% - 99.78%

Forma y color: Solid

Peso molecular: 666.71

Ref: TM-TN2252

Syrosingopine

Producto controlado

CAS: 84-36-6

Applications Syrosingopine (CAS# 84-36-6) is a pharmaceutical used to treat hypertension.
References Woods, J. W.; et al.: Journal of Clinical Investigation, 39, 1813 (1960).

Fórmula: C₃₅H₄₂N₂O₁₁

Pureza: >90%

Forma y color: Neat

Peso molecular: 666.71

Ref: TR-S920068

Syrosingopine

CAS: 84-36-6

Inhibitor of vesicular monoamine transporters with anti-hypertensive properties. Syrosingopine is also inhibitor of monocarboxylate transporters MCT1 and MCT4 and has 60-fold higher potency on MCT4. Syrosingopine inhibits lactate export from cells, causing glycolytic blockade, ATP depletion and cell death. Syrosingopine was shown to sensitise cancer cells to metformin treatment and potentiate its anti-cancer activity.

Fórmula: C₃₅H₄₂N₂O₁₁

Pureza: Min. 90 Area-%

Forma y color: White Powder

Peso molecular: 666.71 g/mol

Ref: 3D-FS65931

Syrosingopine - Bio-X ™

CAS: 84-36-6

Inhibitor of vesicular monoamine transporters with anti-hypertensive properties. Syrosingopine is also inhibitor of monocarboxylate transporters MCT1 and MCT4 and has 60-fold higher potency on MCT4. Syrosingopine inhibits lactate export from cells, causing glycolytic blockade, ATP depletion and cell death. Syrosingopine was shown to sensitise cancer cells to metformin treatment and potentiate its anti-cancer activity.

Fórmula: C₃₅H₄₂N₂O₁₁

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 666.72 g/mol

Ref: 3D-BS300129

SYROSINGOPINE

CAS: 84-36-6

Fórmula: C₃₅H₄₂N₂O₁₁

Pureza: %

Forma y color: Solid

Peso molecular: 666.7148

Ref: IN-DA00G2SK

Syrosingopine

CAS: 84-36-6

Forma y color: Neat

Ref: 61-FOR1970.00