CAS 84000-11-3

N-[(9H-Fluoren-9-ilmetoxi)carbonil]-N-metil-L-valina

Descripción:

N-[(9H-Fluoren-9-ilmetoxi)carbonil]-N-metil-L-valina, comúnmente conocido como Fmoc-N-metil-L-valina, es un compuesto químico ampliamente utilizado en la síntesis de péptidos como grupo protector para aminoácidos. El grupo Fmoc, derivado de fluorenilmetoxicarbonilo, proporciona estabilidad durante el proceso de síntesis y puede ser fácilmente eliminado en condiciones básicas, permitiendo reacciones posteriores. Este compuesto presenta un residuo de valina, que es un aminoácido esencial conocido por sus propiedades hidrofóbicas, contribuyendo a las características generales de los péptidos en los que se incorpora. La presencia del grupo N-metilo aumenta el volumen estérico y puede influir en la conformación de los péptidos resultantes. Fmoc-N-metil-L-valina se utiliza típicamente en la síntesis de péptidos en fase sólida (SPPS), donde ayuda en el ensamblaje selectivo de cadenas de péptidos. Su solubilidad en disolventes orgánicos y estabilidad bajo diversas condiciones de reacción lo convierten en un reactivo valioso en el campo de la química orgánica y medicinal. Al igual que con muchas sustancias químicas, el manejo adecuado y las precauciones de seguridad son esenciales debido a los peligros potenciales asociados con su uso.

Fórmula: C₂₁H₂₃NO₄

InChI: InChI=1/C21H23NO4/c1-13(2)19(20(23)24)22(3)21(25)26-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,13,18-19H,12H2,1-3H3,(H,23,24)/t19-/m0/s1

Clave InChI: InChIKey=YCXXXPZNQXXRIG-IBGZPJMESA-N

SMILES: C(OC(N([C@@H](C(C)C)C(O)=O)C)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Sinónimos:

• (2S)-2-([[(9H-Fluoren-9-yl)methoxy]carbonyl](methyl)amino)-3-methylbutanoic acid
• (2S)-2-[9H-Fluoren-9-ylmethoxycarbonyl(methyl)amino]-3-methylbutanoic acid
• <span class="text-smallcaps">L</span>-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-
• Fmoc-N-Me-Val-OH
• N-(9-Fluorenylmethoxycarbonyl)-N-methylvaline
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-<span class="text-smallcaps">L</span>-valine
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-valine
• N-alpha-(9-fluorenylmethyloxycarbonyl)-N-alpha-Methyl-L-valine
• L-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-
• FMOC-N-ME-VAL 98.5+%
• FMOC-L-MEVAL-OH
• FMOC-N-METHYL-L-VALINE
• FMOC-N-ALPHA-METHYL-L-VALINE
• FMOC-MEVAL-OH
• FMOC-N-ME-L-VAL-OH
• FMOC-N-ME-VALINE
• N-(9-Fluorenylmethyloxycarbonyl)-N-methyl-L-valine
• N-ALPHA(9-FLUORENYLMETHOXYCARBONYL)-N-ALPHA-METHYL-L-VALINE

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-valine

CAS: 84000-11-3

Fórmula: C₂₁H₂₃NO₄

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 353.42

Ref: 3B-F1165

N-Fmoc-N-methyl-L-valine, 95%

CAS: 84000-11-3

N-Fmoc-N-methyl-L-valine is used as enzyme substrates and reagents, culture media additives, dyes, stains and indicators. It is also involved in the preparation of N-methylated peptides. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some docu

Fórmula: C₂₁H₂₃NO₄

Pureza: 95%

Peso molecular: 353.42

Ref: 02-H63671

Fmoc-N-Me-Val-OH

CAS: 84000-11-3

The acid fluoride of this sterically hindered amino acid could be coupled to N-methylated amino acids in HFIP at 55°C.

Fórmula: C₂₁H₂₃NO₄

Pureza: 99.7%

Forma y color: White

Peso molecular: 353.42

Ref: 01-4009586

Fmoc-N-Me-Val-OH

CAS: 84000-11-3

Fórmula: C₂₁H₂₃NO₄

Pureza: 97%

Forma y color: Solid

Peso molecular: 353.4116

Ref: IN-DA005235

Fmoc-N-Me-Val-OH

CAS: 84000-11-3

Fórmula: C₂₁H₂₃NO₄

Pureza: (HPLC) ≥ 98.0%

Forma y color: White to light beige powder

Peso molecular: 353.41

Ref: 7W-GM1535

Fmoc-N-methyl-L-valine

CAS: 84000-11-3

Fmoc-N-methyl-L-valine

Fórmula: C₂₁H₂₃NO₄

Pureza: 98%

Forma y color: white powder

Peso molecular: 353.41g/mol

Ref: 54-OR960386

Fmoc-N-Me-Val-OH

CAS: 84000-11-3

Fmoc-N-Me-Val-OH is a modified peptide.

Fórmula: C₂₁H₂₃NO₄

Forma y color: White Powder

Peso molecular: 353.41

Ref: TM-T19325

Fmoc-N-Me-Val-OH

CAS: 84000-11-3

M03379 - Fmoc-N-Me-Val-OH

Fórmula: C₂₁H₂₃NO₄

Pureza: 97%

Forma y color: Solid, Beige powder

Peso molecular: 353.418

Ref: 10-M03379

Fmoc-N-methyl-L-valine

CAS: 84000-11-3

Fmoc-N-methyl-L-valine is a synthetic immunosuppressant that acts by inhibiting the production of cytokines and other inflammatory mediators. It binds to the enzyme cyclooxygenase, which is involved in the synthesis of prostaglandins and thromboxanes. Fmoc-N-methyl-L-valine has been shown to be effective against gram-positive bacteria. This compound also inhibits xanthine oxidase and may act as an analog for azathioprine, which is used in the treatment of autoimmune diseases such as rheumatoid arthritis. The reaction mechanism for this compound is not well understood but appears to involve a nucleophilic attack on a benzoquinoneiminium cation formed from the attack on an electron deficient benzene ring with a triphosgene electrophile.

Fórmula: C₂₁H₂₃NO₄

Pureza: Min. 95%

Peso molecular: 353.41 g/mol

Ref: 3D-FF32984