CAS 84633-29-4

Euricomanona

Descripción:

Euricomanona es un compuesto natural extraído principalmente de las raíces de la planta Eurycoma longifolia, comúnmente conocida como Tongkat Ali. Se clasifica como un quassinoide, un tipo de compuesto conocido por su sabor amargo y sus posibles propiedades medicinales. Euricomanona es reconocido por sus diversas actividades biológicas, incluyendo posibles efectos afrodisíacos, propiedades anticancerígenas y la capacidad de mejorar el rendimiento atlético al aumentar los niveles de testosterona. El compuesto ha despertado interés en la medicina tradicional y los suplementos dietéticos, particularmente en el sudeste asiático. Su estructura química presenta una disposición compleja de anillos de carbono, lo que contribuye a sus propiedades únicas. Euricomanona se estudia típicamente por sus efectos farmacológicos, incluyendo su papel en la promoción de la salud reproductiva masculina y su potencial para mejorar los niveles de energía y la vitalidad en general. Al igual que con muchos compuestos naturales, se están realizando más investigaciones para comprender completamente sus mecanismos de acción y su potencial terapéutico.

Fórmula: C₂₀H₂₄O₉

InChI: InChI=1S/C20H24O9/c1-7-4-10(21)13(23)17(3)9(7)5-11-18-6-28-20(27,16(17)18)12(22)8(2)19(18,26)14(24)15(25)29-11/h4,9,11-14,16,22-24,26-27H,2,5-6H2,1,3H3/t9-,11+,12+,13+,14-,16+,17+,18+,19-,20-/m0/s1

Clave InChI: InChIKey=UCUWZJWAQQRCOR-OKNZMGBLSA-N

SMILES: O[C@]12[C@@]34[C@@]([C@]5(C)[C@@](C[C@]3(OC(=O)[C@@H]1O)[H])(C(C)=CC(=O)[C@H]5O)[H])([C@@](O)(OC4)[C@H](O)C2=C)[H]

Sinónimos:

• Pasakbumin A
• (1β,11β,12α,15β)-11,20-Epoxy-1,11,12,14,15-pentahydroxypicrasa-3,13(21)-diene-2,16-dione
• Picrasa-3,13(21)-diene-2,16-dione, 11,20-epoxy-1,11,12,14,15-pentahydroxy-, (1β,11β,12α,15β)-
• 2H-1,11c-(Epoxymethano)phenanthro[10,1-bc]pyran, picrasa-3,13(21)-diene-2,16-dione deriv.
• Eurycomanone

Eurycomanone

CAS: 84633-29-4

Fórmula: C₂₀H₂₄O₉

Pureza: 98%

Forma y color: Solid

Peso molecular: 408.3992

Ref: IN-DA00G59J

Eurycomanone

CAS: 84633-29-4

Fórmula: C₂₀H₂₄O₉

Peso molecular: 408.40

Ref: 7W-GY5621

EURYCOMANONE

CAS: 84633-29-4

EURYCOMANONE

Pureza: ≥98%

Peso molecular: 408.4g/mol

Ref: 54-BUP03480

Eurycomanone

CAS: 84633-29-4

Eurycomanone has cytotoxic on HepG2 cells and Human Cervical Carcinoma Cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2.[1,2]

Fórmula: C₂₀H₂₄O₉

Pureza: 95%~99%

Forma y color: Cryst.

Peso molecular: 408.403

Ref: BP-BP1784

EURYCOMANONE

CAS: 84633-29-4

Eurycomanone (Pasakbumin A) is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2.

Fórmula: C₂₀H₂₄O₉

Pureza: 98.15% - 99.95%

Forma y color: Solid

Peso molecular: 408.4

Ref: TM-T7027

Eurycomanone

CAS: 84633-29-4

Oxygen-heterocyclic compound

Fórmula: C₂₀H₂₄O₉

Pureza: ≥ 90.0 % (HPLC)

Forma y color: Powder

Peso molecular: 408.4

Ref: 5G-85739

Eurycomanone

Producto controlado

CAS: 84633-29-4

Applications Eurycomanone is known as a cytotoxic compound found in Eurycoma Longifolia Jack. Previous studies had noted its cytotoxic effects against various cancer cell lines. More recent research demonstrated the ability of Eurycomanone to suppress the expression of lung cancer cell tumor markers, prohibitin, annexin 1 and endoplasmic reticulum protein 28. Eurycomanone was shown to also exerts the ability to induce apoptosis through the up-regulation of p53 in human cervical carcinoma cells.
References Wong, P.F., et al.: Phytomed., 19, 138 (2012); Nurkhasanah, M., et al., Medunion Press., 4, 109 (2008); Zakaria, Y., et al.: Cancer Cell Intern., 9, (2009);

Fórmula: C₂₀H₂₄O₉·2H₂O

Pureza: >90%

Forma y color: Neat

Peso molecular: 444.43

Ref: TR-E939010

Eurycomanone - Bio-X ™

CAS: 84633-29-4

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Fórmula: C₂₀H₂₄O₉

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 408.4 g/mol

Ref: 3D-BE300078

Eurycomanone

CAS: 84633-29-4

Eurycomanone is a natural product that belongs to the group of quassinoids. It is obtained from the plant Eurycoma longifolia, which grows in tropical Asia and Africa. The extract has been shown to have clinical properties such as body formation, protein target, and surface methodology. 3T3-L1 preadipocytes were used for the in vitro assays of eurycomanone. Group P2 cells were used for histological analysis and pharmacological agents were found to be chemical stable.

Fórmula: C₂₀H₂₄O₉

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 408.4 g/mol

Ref: 3D-FE74396