CAS 84676-89-1

Astragalósido II

Descripción:

Astragalósido II, con el número CAS 84676-89-1, es un glucósido natural derivado principalmente de la raíz de Astragalus membranaceus, una planta comúnmente utilizada en la medicina tradicional. Este compuesto se caracteriza por su composición estructural, que incluye una porción de azúcar unida a un aglicona esteroidal. Astragalósido II es conocido por sus posibles propiedades farmacológicas, incluyendo efectos inmunomoduladores, antiinflamatorios y antioxidantes. Se ha estudiado por su papel en la mejora de la función inmunológica y la promoción de la salud celular. Además, la investigación sugiere que puede tener efectos protectores contra el estrés oxidativo y podría apoyar la salud cardiovascular. El compuesto es típicamente soluble en disolventes polares, y su estabilidad puede verse influenciada por factores como el pH y la temperatura. Como un compuesto bioactivo, Astragalósido II es de interés tanto en la investigación farmacológica como en la medicina herbal, aunque se necesitan más estudios para elucidar completamente sus mecanismos de acción y potencial terapéutico.

Fórmula: C₄₃H₇₀O₁₅

InChI: InChI=1/C43H70O15/c1-21(45)54-29-28(48)23(47)19-53-34(29)58-43(52)32(49)25(18-44)56-35(33(43)50)55-24-16-26-39(7)17-22(46)30(40(8)13-10-27(57-40)37(4,5)51)38(39,6)14-15-41(26)20-42(41)12-9-11-36(2,3)31(24)42/h22-35,44,46-52H,9-20H2,1-8H3/t22-,23+,24-,25+,26?,27-,28-,29+,30-,31?,32+,33-,34-,35+,38+,39-,40+,41?,42+,43+/m0/s1

Clave InChI: InChIKey=AYWNHWGQTMCQIV-PENCHUSISA-N

SMILES: C[C@]12[C@]3([C@]4([C@]5(C4)[C@@]([C@@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C3)(C(C)(C)[C@@H](O[C@H]7[C@H](OC(C)=O)[C@@H](O)[C@H](O)CO7)CC5)[H])CC[C@]1(C)[C@]([C@@H](O)C2)([C@]8(C)O[C@H](C(C)(C)O)CC8)[H])[H]

Sinónimos:

• (2S,3R,4S,5R)-4,5-dihydroxy-2-{[(2R,3S,4R,5R,6R)-3,4,5-trihydroxy-2-({(1R,2S,3aS,5S,9aR,12aR)-2-hydroxy-1-[(2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyltetrahydrofuran-2-yl]-3a,6,6,12a-tetramethyltetradecahydro-1H-cyclopenta[a]cyclopropa[e]phenanthren-5-yl}oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}tetrahydro-2H-pyran-3-yl acetate (non-preferred name)
• (3β,6α,16β,20R,24S)-3-[(2-O-Acetyl-β-<span class="text-smallcaps">D</smallcap>-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl β-<smallcap>D</span>-glucopyranoside
• 1H,19H-Cyclopropa[9,10]cyclopenta[a]phenanthrene, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• 9,19-Cyclolanostane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• Astrasieversianin VIII
• NSC 641295
• astragalosideⅡ
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,6α,16β,20R,24S)-3-[(2-O-acetyl-β-<smallcap>D</span>-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl
• 1H,19H-Cyclopropa[9,10]cyclopenta[a]phenanthrene, β-D-glucopyranoside deriv.
• (3β,6α,16β,20R,24S)-3-[(2-O-Acetyl-β-D-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl β-D-glucopyranoside
• Astragaloside II
• 9,19-Cyclolanostane, β-D-glucopyranoside deriv.
• β-D-Glucopyranoside, (3β,6α,16β,20R,24S)-3-[(2-O-acetyl-β-D-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl
• Astragaloside II
• (3b,6a,16b,20r,24s)-3-((2-o-acetyl-beta-d-xylopyranosyl)oxy)-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl beta-d-glucopyranoside
• Astragaloside II USP/EP/BP
• Cyclosiversioside D
• Astragaloside II 84676-89-1
• Astragaloside II (Astrasieversianin VIII)
• Astragaloside B
• 16,25-dihydroxy-9,19-cyclolanostan-6-yl
• Astragalin Astragaloside II
• Cyclosieversioside D
• ASTRAGALOSIDE II(SH)
• 3-[(2-O-acetyl-β-D-xylopyranosyl)oxy]-20,24-epoxy-

β-​D-​Glucopyranoside, (3β,​6α,​16β,​20R,​24S)​-​3-​[(2-​O-​acetyl-​β-​D-​xylopyranosyl)​oxy]​-​20,​24-​epoxy-​16,​25-​dihydroxy-​9,​19-​cyclolanostan-​6-​yl

CAS: 84676-89-1

Fórmula: C₄₃H₇₀O₁₅

Pureza: 98%

Forma y color: Solid

Peso molecular: 827.0069

Ref: IN-DA003NXK

Astragaloside II

CAS: 84676-89-1

Astragaloside II

Pureza: ≥98%

Peso molecular: 827.01g/mol

Ref: 54-BUP02941

Astragaloside II

CAS: 84676-89-1

Ref: 7W-GC0586

Astragaloside II

CAS: 84676-89-1

Astragaloside II can downregulate the expression of the P-gp and mdr1 gene, suppress phosphorylation of extracellular signal regulated kinase 1/2, p38 and c-Jun N-terminal kinase, suggests that Astragaloside II is a potent multidrug resistance (MDR) reversal agent and may be a potential adjunctive agent for hepatic cancer chemotherapy.

Fórmula: C₄₃H₇₀O₁₅

Pureza: 95%~99%

Forma y color: Powder

Peso molecular: 827.018

Ref: BP-BP0211

Astragaloside II

CAS: 84676-89-1

Astragaloside II: Potent for MDR, hepatic cancer therapy; boosts osteogenesis via BMP-2/MAPK, Smad1/5/8 pathways.

Fórmula: C₄₃H₇₀O₁₅

Pureza: 98.54% - 99.7%

Forma y color: Solid

Peso molecular: 827.01

Ref: TM-T3924

Astragaloside ii

CAS: 84676-89-1

Natural glycoside

Fórmula: C₄₃H₇₀O₁₅

Pureza: ≥ 98.0 % (HPLC)

Forma y color: Powder

Peso molecular: 827.02

Ref: 5G-89573

Astragaloside II

Producto controlado

CAS: 84676-89-1

Applications Astragaloside II has cardioprotective effects as well as causing improvement in cognitive function. Used in the prevention of cardio-cerebral vascular diseases.
References Shaw, L et al.: PLoS One, 7, e3848 (2012); Kong, X. et al.: Int. J. Mol. Med., 29, 1090 (2012);

Fórmula: C₄₃H₇₀O₁₅

Forma y color: Neat

Peso molecular: 827.01

Ref: TR-A790140

Astragaloside II

CAS: 84676-89-1

Astragaloside II is a natural compound that has been shown to have anti-inflammatory effects in vitro and in vivo. Astragaloside II inhibits the production of inflammatory mediators by inhibiting phosphodiesterase and cyclooxygenase pathways. It also has a matrix effect on the cells, which may be due to its ability to activate protein kinase C. This compound also has an analytical method, which consists of HPLC with UV detection at 210 nm.

Fórmula: C₄₃H₇₀O₁₅

Pureza: Min. 95%

Forma y color: White To Off-White Solid

Peso molecular: 827.01 g/mol

Ref: 3D-MA09407