CAS 847-86-9

4-hidroxi-3-metoxi-17-metilmorfinan-6-ona

Descripción:

4-hidroxi-3-metoxi-17-metilmorfinan-6-ona, comúnmente conocido como derivado de morfina, es un opioide semisintético con notables propiedades analgésicas. Este compuesto se caracteriza por su compleja estructura morfinana, que incluye un grupo hidroxilo en la posición 4 y un grupo metoxi en la posición 3, contribuyendo a su actividad farmacológica. La presencia de una cetona en la posición 6 y un grupo metilo en la posición 17 define aún más su identidad química. Exhibe una alta afinidad por los receptores opioides, particularmente el receptor mu-opioide, que es responsable de sus efectos analgésicos. El compuesto se administra típicamente en entornos controlados debido a su potencial de adicción y efectos secundarios, incluyendo depresión respiratoria y sedación. Su solubilidad en disolventes orgánicos y su limitada solubilidad en agua son importantes para consideraciones de formulación en aplicaciones farmacéuticas. En general, 4-hidroxi-3-metoxi-17-metilmorfinan-6-ona es significativo en la química medicinal, particularmente en el desarrollo de analgésicos y la comprensión de las interacciones de los receptores opioides.

Fórmula: C₁₈H₂₃NO₃

InChI: InChI=1/C18H23NO3/c1-19-8-7-18-10-12(20)4-5-13(18)14(19)9-11-3-6-15(22-2)17(21)16(11)18/h3,6,13-14,21H,4-5,7-10H2,1-2H3/t13-,14-,18+/m0/s1

Clave InChI: InChIKey=CDGFTOARGCEWKI-IYOUNJFTSA-N

SMILES: OC1=C2[C@@]34[C@]([C@@](CC2=CC=C1OC)(N(C)CC3)[H])(CCC(=O)C4)[H]

Sinónimos:

• 2H-10,4a-Iminoethanophenanthren-3(4H)-one, 1,9,10,10a-tetrahydro-5-hydroxy-6-methoxy-11-methyl-
• 4-Hydroxy-3-methoxy-N-methyl-6-oxomorphinan
• 7,8-Dihydrothebainone
• 7,8-Dihydrothebainone A
• Dihydrothebainone
• Dihydrothebainone A
• Dihydrothobainone
• Morphinan, 4-hydroxy-3-methoxy-N-methyl-6-oxo-
• Morphinan-6-one, 4-hydroxy-3-methoxy-17-methyl-
• Nsc 134598
• Nsc 35545
• Ram-345
• Thebainone, dihydro-
• 4-Hydroxy-3-methoxy-17-methylmorphinan-6-one
• 4-Hydroxy-3-methoxy-17-methylmorphinan-6-one
• Hydrocodone Related CoMpound A CII
• 4-hydroxy-3-methoxy-n-methyl-6-oxo-morphina
• 4-hydroxy-3-methoxy-17-methyl-morphinan-6-on
• 3-Methoxy-4-hydroxy-6-oxo-17-methylmorphinan
• 1,9,10,10a-Tetrahydro-5-hydroxy-6-Methoxy-11-Methyl-2H-10,4a-iMinoethanophenanthren-3(4H)-one
• HYDROCODONE BITARTRATE RELATED COMPOUND A CII (70 MG) (MORPHINAN-6-ONE, 4-HYDROXY-3-METHOXY-17-METHYL)
• Hydrocodone Related Compound A CII (70 mg) (4-hydroxy-3-methoxy-17-methylmorphinan-6-one) (1315012)
• Hydrocodone Bitartrate Related Compound A CII (70 mg) (Morphinan-6-one, 4-hydroxy-3-methoxy-17-methyl)
• Oxycodone Hydrochloride Impurity 10

(-)-Dihydrothebainone

Producto controlado

CAS: 847-86-9

Fórmula: C₁₈H₂₃NO₃

Forma y color: Neat

Peso molecular: 301.38

Ref: TR-D449820

Hydrocodone

Producto controlado

CAS: 847-86-9

Hydrocodone is a narcotic analgesic that binds to opioid receptors in the body. It is a semi-synthetic opioid derived from codeine, which is obtained from the opium poppy. Hydrocodone has been shown to have higher affinity for mu-opioid receptors than other opioids such as morphine, and it also has less affinity for kappa- and delta-receptors. Hydrocodone has a concentration–time curve that can be described by three phases: an initial rapid elimination phase, followed by a slower elimination phase with a plateau effect, and finally an elimination phase with decreasing concentrations. Hydrocodone may interact with nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin or ibuprofen, since NSAIDs inhibit the enzyme cyclooxygenase 1 (COX1), which is responsible for conversion of arachidonic acid to prostaglandins that produce pain and inflammation. Hydrocodone may also interact

Fórmula: C₁₈H₂₃NO₃

Pureza: Min. 95%

Peso molecular: 301.4 g/mol

Ref: 3D-AAA84786

Hydrocodone Related Compound A CII (4-hydroxy-3-methoxy-17-methylmorphinan-6-one)

Producto controlado

CAS: 847-86-9

Alkaloids of opium and their derivatives, salts thereof

Fórmula: C₁₈H₂₃NO₃

Forma y color: White Powder

Peso molecular: 301.16779

Ref: 45-1315012