CAS 85-61-0

Coenzima A

Descripción:

Coenzima A (CoA) es un cofactor vital en varias reacciones bioquímicas, involucrado principalmente en el metabolismo de ácidos grasos y carbohidratos. Es una molécula compleja compuesta de adenosina, ácido pantoténico (vitamina B5) y un grupo mercaptoetilamina. CoA juega un papel crucial en la formación de acetil-CoA, que es un sustrato clave para el ciclo del ácido cítrico, facilitando la producción de energía en las células. La sustancia se caracteriza por su capacidad para formar enlaces tioéster, que son esenciales para la activación de grupos acilo en las vías metabólicas. Coenzima A es soluble en agua y exhibe un alto grado de reactividad debido a la presencia de su grupo tiol, lo que le permite participar en varias reacciones enzimáticas. Su estructura le permite actuar como transportador de grupos acilo, haciéndolo indispensable en la síntesis y degradación de ácidos grasos y el metabolismo de aminoácidos. En general, Coenzima A es integral para el metabolismo energético celular y la síntesis de biomoléculas importantes.

Fórmula: C₂₁H₃₆N₇O₁₆P₃S

InChI: InChI=1S/C21H36N7O16P3S/c1-21(2,16(31)19(32)24-4-3-12(29)23-5-6-48)8-41-47(38,39)44-46(36,37)40-7-11-15(43-45(33,34)35)14(30)20(42-11)28-10-27-13-17(22)25-9-26-18(13)28/h9-11,14-16,20,30-31,48H,3-8H2,1-2H3,(H,23,29)(H,24,32)(H,36,37)(H,38,39)(H2,22,25,26)(H2,33,34,35)/t11-,14-,15-,16+,20-/m1/s1

Clave InChI: InChIKey=RGJOEKWQDUBAIZ-IBOSZNHHSA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](COP(OP(OCC([C@H](C(NCCC(NCCS)=O)=O)O)(C)C)(=O)O)(=O)O)[C@H]1OP(=O)(O)O

Sinónimos:

• <span class="text-smallcaps">D</span>-Coenzyme A
• Adenosine 5'-(trihydrogen diphosphate) 3'-(dihydrogen phosphate) P'-[(R)-3-hydroxy-4-[[3-[(2-mercaptoethyl)amino]-3-oxopropyl]amino]-2,2-dimethyl-4-oxobutyl] ester
• Adenosine 5'-(trihydrogen diphosphate), 3'-(dihydrogen phosphate), P'-[3-hydroxy-4-[[3-[(2-mercaptoethyl)amino]-3-oxopropyl]amino]-2,2-dimethyl-4-oxobutyl] ester, (R)-
• Aluzime
• COA
• CoASH
• Coa-Sh
• Coalip
• Coenzym A
• Coenzyme A Free Acid From Yeast
• Coenzyme A Hydrate
• Coenzyme A, free acid, lyophilized, 75%
• Coenzyme A, free acid, lyophilized, min. 75% (enzym.)
• Coenzyme ASH
• Coenzyme a, free acid
• D-Coenzyme A
• Lucina
• Reduced CoA
• Thiol-CoA
• [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl dihydrogen diphosphate (non-preferred name)
• [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3S)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl dihydrogen diphosphate (non-preferred name)
• [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl 3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl dihydrogen diphosphate (non-preferred name)
• coenzima A

Coenzyme A

CAS: 85-61-0

Coenzyme A

Pureza: ≥90%

Peso molecular: 767.53g/mol

Ref: 54-BUP15611

Coenzyme A Free Acid

CAS: 85-61-0

Coenzyme A Free Acid

Fórmula: C₂₁H₃₆N₇O₁₆P₃S

Pureza: ≥95.0%

Peso molecular: 767.53g/mol

Ref: 54-BIA0812

Coenzyme A hydrate

CAS: 85-61-0

Fórmula: C₂₁H₃₆N₇O₁₆P₃S·xH₂O

Pureza: ≥ 90.0%

Forma y color: White to off-white or pale yellow powder

Peso molecular: 767.53 (anhydrous)

Ref: 7W-GK0114

Coenzyme A

CAS: 85-61-0

Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine.

Fórmula: C₂₁H₃₆N₇O₁₆P₃S

Pureza: 93.84%

Forma y color: Solid

Peso molecular: 767.53

Ref: TM-T10857

Coenzyme A free acid

CAS: 85-61-0

Fórmula: C21H36N7O16P3S

Pureza: >94%

Forma y color: Solid

Peso molecular: 767.54

Ref: 48-19-1001

Coenzyme A hydrate

CAS: 85-61-0

Coenzyme A hydrate is essential in the metabolism of fatty acids and the synthesis of acetyl-CoA. It is also employed in pharmaceutical applications, especially in drug development and formulation. Its distinctive properties improve drug solubility and bioavailability, making it an essential component in the creation of therapeutic agents.

Fórmula: C₂₁H₃₆N₇O₁₆P₃S·xH₂O

Pureza: (Enzymatic) Min. 75%

Forma y color: White Off-White Slightly Yellow Powder

Peso molecular: 767.54 g/mol

Ref: 3D-NC45965

Coenzyme A Free Acid extrapure, 90%

CAS: 85-61-0

Fórmula: C₂₁H₃₆N₇O₁₆P₃S

Pureza: min. 90%

Forma y color: Almost white to slightly yellowish, Lyophilized powder

Peso molecular: 767.54

Ref: SR-40804

Coenzyme A, Free Acid

CAS: 85-61-0

Pureza: 95%

Peso molecular: 767.115

Ref: 10-C300023

Coenzyme A S-Pyrazinecarboxylate Trisodium Salt

Producto controlado

CAS: 85-61-0

Applications Coenzyme A S-Pyrazinecarboxylate is a derivative of Coenzyme A (C636400); a cofactor in enzymatic acetyl transfer reactions. It is the source of the phosphopantetheine group that is added as a prosthetic group to proteins such as acyl carrier protein and formyltetrahydrofolate dehydrogenase.
References Strickland K.C. et al.: J. Biol. Chem., 285, 1627 (2010); Elovson J. et al.: J. Biol. Chem., 243, 3603 (1968)

Fórmula: C₂₆H₃₅N₉Na₃O₁₇P₃S

Forma y color: Neat

Peso molecular: 939.56

Ref: TR-C636415