CAS 850649-61-5

Alogliptina

Descripción:

Alogliptina es un agente antihiperglucémico oral que pertenece a la clase de inhibidores de la dipeptidil peptidasa-4 (DPP-4), utilizado principalmente en el manejo de la diabetes mellitus tipo 2. Su mecanismo de acción implica la inhibición de la enzima DPP-4, lo que lleva a un aumento de los niveles de hormonas incretinas, mejorando así la secreción de insulina y reduciendo los niveles de glucagón de manera dependiente de la glucosa. Esto ayuda a disminuir los niveles de glucosa en sangre. Alogliptina se caracteriza por su fórmula química, que incluye elementos como carbono, hidrógeno, nitrógeno y oxígeno, contribuyendo a su estructura molecular específica. Se administra típicamente en forma de tabletas y a menudo se prescribe en combinación con otros medicamentos antidiabéticos para mejorar el control glucémico. Alogliptina generalmente es bien tolerado, con un perfil de efectos secundarios que puede incluir trastornos gastrointestinales y un riesgo potencial de pancreatitis. Al igual que con cualquier medicamento, es esencial que los pacientes consulten a profesionales de la salud para obtener asesoramiento personalizado y monitoreo mientras utilizan Alogliptina.

Fórmula: C₁₈H₂₁N₅O₂

InChI: InChI=1S/C18H21N5O2/c1-21-17(24)9-16(22-8-4-7-15(20)12-22)23(18(21)25)11-14-6-3-2-5-13(14)10-19/h2-3,5-6,9,15H,4,7-8,11-12,20H2,1H3/t15-/m1/s1

Clave InChI: InChIKey=ZSBOMTDTBDDKMP-OAHLLOKOSA-N

SMILES: C(N1C(=CC(=O)N(C)C1=O)N2C[C@H](N)CCC2)C3=C(C#N)C=CC=C3

Sinónimos:

• (R)-2-[6-[3-Aminopiperidin-1-yl]-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-ylmethyl]benzonitrile
• 2-[[6-[(3R)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]benzonitrile
• 2-[[6-[(3R)-3-Aminopiperidin-1-yl]-3-methyl-2,4-dioxopyrimidin-1-yl]methyl]benzonitrile
• Alogliptin(Alogliptine, Alogliptina)
• Benzonitrile, 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-
• Vipidia
• Alogliptin

(R)​-​2-​[6-​[3-​Aminopiperidin-​1-​yl]​-​3-​methyl-​2,​4-​dioxo-​1,​2,​3,​4-​tetrahydropyrimidin-​1-​ylmethyl]​benzonitrile

CAS: 850649-61-5

Fórmula: C₁₈H₂₁N₅O₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 339.3916

Ref: IN-DA00IDIW

Alogliptin

CAS: 850649-61-5

Fórmula: C₁₈H₂₁N₅O₂

Peso molecular: 339.40

Ref: 4Z-A-4949

Alogliptin

CAS: 850649-61-5

Alogliptin

Pureza: ≥98%

Peso molecular: 339.39g/mol

Ref: 54-BUP08626

Alogliptin

CAS: 850649-61-5

Alogliptin

Pureza: 98%

Peso molecular: 339.397g/mol

Ref: 54-OR1027745

Alogliptin

CAS: 850649-61-5

Forma y color: Neat

Ref: 86-MM3928.00

Alogliptin

CAS: 850649-61-5

Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9

Fórmula: C₁₈H₂₁N₅O₂

Pureza: 99.63%

Forma y color: Solid

Peso molecular: 339.39

Ref: TM-T6192

Alogliptin

Producto controlado

CAS: 850649-61-5

Applications Alogliptin is an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4).Antidiabetic agent.
References Lynn, F., et al.: Diabetes, 50, 1004 (2001); Trumper, A., et al.: J. Endocrinol., 174, 233 (2002); Vollmer, K., et al.: J. Clin. Endocrinol. Metab., 94, 1379 (2009);

Fórmula: C₁₈H₂₁N₅O₂

Forma y color: White

Peso molecular: 339.39

Ref: TR-A575425

ALOGLIPTIN

CAS: 850649-61-5

Fórmula: C₁₈H₂₁N₅O₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 339.399

Ref: 10-F468425

Alogliptin

CAS: 850649-61-5

Alogliptin is a drug that belongs to the class of glp-1 receptor agonists. It is used for the treatment of type 2 diabetes and can be prescribed alone or in combination with other drugs. Alogliptin has been shown to stimulate the production and release of peptide hormones, such as glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), which are important for the regulation of blood sugar levels. The drug also stimulates insulin release from pancreatic beta cells in response to blood sugar levels, which is necessary for maintaining normal blood sugar levels. Alogliptin has an effect on congestive heart failure by increasing cardiac output through improved contractility, as well as on gut motility through its activity on toll-like receptors.

Fórmula: C₁₈H₂₁N₅O₂

Pureza: Min. 95 Area-%

Forma y color: Powder

Peso molecular: 339.39 g/mol

Ref: 3D-FA17319