CAS 85622-93-1
:Temozolomida
Descripción:
Temozolomida es un agente alquilante oral que se utiliza principalmente en el tratamiento de ciertos tipos de tumores cerebrales, particularmente el glioblastoma multiforme y el astrocitoma anaplásico. Su fórmula química es C6H6N4O2, y se clasifica como un profármaco, lo que significa que se metaboliza en el cuerpo a su forma activa, que luego ejerce sus efectos terapéuticos. Temozolomida actúa metilando el ADN, lo que lleva a la interrupción de la replicación del ADN y, en última instancia, induce la apoptosis en células cancerosas que se dividen rápidamente. La sustancia se administra típicamente en forma de cápsulas y es conocida por su capacidad para cruzar la barrera hematoencefálica, lo que la hace efectiva para tumores del sistema nervioso central. Temozolomida generalmente es bien tolerada, pero puede causar efectos secundarios como náuseas, vómitos y mielosupresión. Su farmacocinética implica una rápida absorción y metabolismo, con una vida media que permite horarios de dosificación convenientes. En general, Temozolomida representa un avance significativo en el manejo quimioterapéutico de tumores cerebrales malignos.
Fórmula:C6H6N6O2
InChI:InChI=1S/C6H6N6O2/c1-11-6(14)12-2-8-3(4(7)13)5(12)9-10-11/h2H,1H3,(H2,7,13)
Clave InChI:InChIKey=BPEGJWRSRHCHSN-UHFFFAOYSA-N
SMILES:C(N)(=O)C1=C2N(C(=O)N(C)N=N2)C=N1
Sinónimos:- 3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide
- 3-Methyl-4-oxo-3,4-dihydro-imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid amide
- 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
- 3-Methyl-4-oxo-3H,4H-imidazo[4,3-d][1,2,3,5]tetrazine-8-carboxamide
- 3-Methyl-4-oxo-8-imidazolo[5,1-d][1,2,3,5]tetrazinecarboxamide
- 3-Methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
- 3-Methyl-8-carbamoylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one
- 4-Methyl-5-oxo-2,3,4,6,8-pentazabicyclo[4.3.0]nona-2,7,9-triene-9-carboxamide
- 8-Carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one
- Ccrg 81045
- Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3,4-dihydro-3-methyl-4-oxo-
- M and B 39831
- Mb 39831
- Methazolastone
- NSC 362856
- Sch 52365
- T 2577
- Temodal
- Temodar
- Temomedac
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Encontrado 14 productos.
Temozolomide
CAS:Fórmula:C6H6N6O2Pureza:>98.0%(HPLC)Forma y color:White to Light yellow to Light red powder to crystalPeso molecular:194.15Temozolomide
CAS:Heterocyclic compounds with nitrogen hetero-atom(s) only, excluding aromatic or modified aromaticFórmula:C6H6N6O2Forma y color:PowderPeso molecular:194.055223-methyl-4-oxo-3H,4H-imidazo[4,3-d][1,2,3,5]tetrazine-8-carboxamide
CAS:Fórmula:C6H6N6O2Pureza:98%Forma y color:SolidPeso molecular:194.1508Temozolomide
CAS:Temozolomide (TMZ) is a DNA alkylating agent with blood-brain barrier permeability and oral activity.Fórmula:C6H6N6O2Pureza:98% - 99.87%Forma y color:Off-White To Light-Pink Crystalline SolidPeso molecular:194.15Temozolomide
CAS:TemozolomideFórmula:C6H6N6O2Pureza:98%Forma y color: white solidPeso molecular:194.15g/molTemozolomide
CAS:Fórmula:C6H6N6O2Pureza:≥ 98.0%Forma y color:White to light-brown or pink powderPeso molecular:194.153-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
CAS:Fórmula:C6H6N6O2Pureza:95%Forma y color:SolidPeso molecular:194.154Temozolomide
CAS:<p>Temozolomide is a cancer drug that belongs to the class of alkylating agents. It has been shown to have anticancer activity against human tumor cells in vitro. Temozolomide induces cell death by activating the apoptotic pathway. This drug also inhibits the cell cycle and blocks the G2-M phase, resulting in accumulation of cells at this point in the cell cycle. Temozolomide has been studied for its effects for cancer treatment in certain research approaches.</p>Fórmula:C6H6N6O2Pureza:Min. 98 Area-%Forma y color:Off-White PowderPeso molecular:194.15 g/molTemozolomide - Bio-X ™
CAS:<p>Temozolomide is an imidazotetrazine alkylating agent. It has anti-tumor activity against a broad spectrum of tumors, such as leukemias, lymphomas and solid tumors. Temozolomide induces G2/M arrest, preventing cells from entering mitosis and, therefore, apoptosis. As a drug resistance-modifying agent it is used for studying drug resistance mechanisms in glioblastoma cell lines.</p>Fórmula:C6H6N6O2Pureza:Min. 98 Area-%Forma y color:White To Pale Pink SolidPeso molecular:194.15 g/mol
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