CAS 863329-66-2
:(2′R)-2′-Desoxi-2′-fluoro-2′-metiluridina
Descripción:
(2′R)-2′-Desoxi-2′-fluoro-2′-metiluridina es un nucleósido modificado que presenta un átomo de flúor y un grupo metilo en la posición 2′ del azúcar ribosa, lo que lo distingue de los nucleósidos naturales. Este compuesto se caracteriza por sus modificaciones estructurales que mejoran su estabilidad y bioactividad, lo que lo hace de interés en la química medicinal y la biología molecular. La presencia del átomo de flúor puede influir en la interacción del compuesto con ácidos nucleicos y enzimas, mejorando potencialmente su eficacia como agente antiviral o anticancerígeno. Además, el grupo metilo puede afectar la solubilidad y permeabilidad del compuesto, que son factores críticos para aplicaciones terapéuticas. La estereoquímica en la posición 2′ (designada como (2′R)) indica una disposición espacial específica que puede impactar la actividad biológica y el reconocimiento por las polimerasas de ácidos nucleicos. En general, (2′R)-2′-Desoxi-2′-fluoro-2′-metiluridina representa una herramienta valiosa para la investigación y el desarrollo en análogos de nucleósidos.
Fórmula:C10H13FN2O5
InChI:InChI=1S/C10H13FN2O5/c1-10(11)7(16)5(4-14)18-8(10)13-3-2-6(15)12-9(13)17/h2-3,5,7-8,14,16H,4H2,1H3,(H,12,15,17)/t5-,7-,8-,10-/m1/s1
Clave InChI:InChIKey=ARKKGZQTGXJVKW-VPCXQMTMSA-N
SMILES:C[C@]1(F)[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C=C2
Sinónimos:- (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine
- (2'R)-2'-deoxy-2'-fluoro-2'-methyl-Uridine
- (2R)-2-Deoxy-2-fluoro-2-methyluridine
- 1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
- 2'-Deoxy-2'-Fluoro-2'-C-Methyl Uridine
- 2'-Deoxy-2'-Fluoro-2'-Methyluridine
- 2-Deoxy-2-Fluoro-2-Methyl Uridine
- Gs 331007
- Psi-6206
- Ro 2433
- Sofosbuvir N-1
- Uridine, 2′-deoxy-2′-fluoro-2′-methyl-, (2′R)-
- Sofosbuvir Intermediate 4
- (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine>
- N4-Benzoyl-1-(2'
- -deoxy-6-methoxyguanosine
- -fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine
- -fluoro-b-D-arabinofuranosyl)purine
- -O-trityl-b-L-lyxofuranosyl)-uracil
- (2'R)-2'-deoxy-2'-fluoro-2'-C-methyluridine
- -fluoro-b-D-arabinofuranosyl)cytosine HCl
- -fluoro-b-D-arabinofuranosyl)-5-ethyluracil
- -deoxy-7-ethynyladenosine
- 5. (2'R)-2'-Deoxy-2'-fluoro-2'-Methyluridine
- -biphenyl]-4-yl]methyl]-4-methyl-2-propyl-1H-benzimidazole-6-carboxylic Acid Methyl Ester
- -fluoro-b-D-arabinofuranosyl)guanine
- -fluoro-b-D-arabinofuranosyl)cytosine
- -(2,5-Dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1'
- -biphenyl]-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylic Acid
- 1-(2'
- PSI 6206 int
- -deoxy-7-iodoguanosine
- -fluoro-b-D-ribofuranosyl)-2-fluoroadenine
- -fluoro-b-D-arabinofuranosyl)-5-iodouracil
- 1-[(2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyl-tetrahydrofuran-2-yl]pyrimidine-2,4-dione
- 2-Fluoro-9-(2'
- 7-Deaza-2'
- -fluoro-beta-d-arabinofuranosyl)-5-ethyluracil
- -fluoroguanosine
- Uridine, 2'-deoxy-2'-fluoro-2'-Methyl-, (2'R)-
- 9-(2'
- 2'-deoxy-2'-fluoro-2'-C-methyluridine ISO 9001：2015 REACH
- Sofosbuvir Nucleoside Derivative (GS-331007)
- -fluoro-b-D-arabinofuranosyl)hypoxantine
- (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine (Sofo C1)
- dcoxy-2-fuoro-2-C-methyhurdine
- -(Methoxycarbonyl)[1,1'
- -fluoro-b-L-arabinofuranosyl)-uracil
- -chloro-b-L-arabinofuranosyl)-thymine
- -fluoro-b-D-arabinofuranosyl)adenine
- -fluoro-b-D-arabinofuranosyl)thymine 3'
- -biphenyl]-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylic Acid-d5
- -O-trityl-b-L-arabinofuranosyl)-uracil
- -fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'
- 2'-deoxy-2'-fluoro-2'-C-methyluridine
- 1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
- Sofosbuvir int. N-1
- -deoxy-O6-methylguanosine
- PSI-6206 (RO-2433, GS-331007)
- 2'-DEOXY-2'-FLUORO-2'-C-METHYLURIDINE,CAS 863329-66-2
- Uridine, 2'-deoxy-2'-fluoro-2'-Methyl-, (2'R)- PSI6206
- Sofosbuvir INT 1
- 2'-Deoxy-2'-F-2'-C-methyluridine
- -deoxy-7-iodoadenosine
- Sofosbuvir imp-11
- -fluoro-a-L-arabinofuranosyl)-thymine
- 2'-Deoxy-2-floro-2'Methyl-uridine
- -deoxy-2'
- 1-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione RO 2433
- -C-ethynyladenosine
- -(Aminoiminomethyl)[1,1'
- Sofosbuvir Metabolite GS331007
- Sofosbuvir Intermediates 2
- PSI-6206; RO-2433; PSI6206; RO2433
- -biphenyl-4-yl)methyl]-2-ethoxy-d5-7-benzimidazolecarboxylic Acid Methyl Ester
- 1-((2S,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione
- -fluoro-b-D-ribofuranosyl)purine
- CS-832
- -O-4-C-Methylene-b-D-ribofuranosyl)thymine
- -biphenyl-4-yl)methyl]-2-ethoxy-7-benzimidazolecarboxylic Acid Methyl Ester
- -fluoro-b-D-ribofuranosyl)-isoguanine
- β-D-2'-deoxy-2'-α-F-2'-β-C-methyluridine
- -C-methyluridine
- -fluoro-b-D-arabinofuranosyl)uracil 3'
- 2'-deoxy-2'-fluoro-2'-C-Methyluridine (N-1)
- -biphenyl]-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylic acid (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester
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Encontrado 10 productos.
PSI-6206
CAS:Fórmula:C10H13FN2O5Pureza:>98.0%(T)(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:260.22(2'R)-2'-Deoxy-2'-fluoro-2'-methyl-uridine
CAS:Fórmula:C10H13FN2O5Pureza:97%Forma y color:SolidPeso molecular:260.2190(2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine
CAS:(2'R)-2'-Deoxy-2'-fluoro-2'-methyluridinePureza:98%Peso molecular:260.22g/molSofosbuvir Nucleoside Derivative (GS-331007)
CAS:Fórmula:C10H13FN2O5Forma y color:Off-White To Yellow SolidPeso molecular:260.22PSI-6206
CAS:PSI-6206 (RO 2433) (RO2433) is a selective HCV RNA polymerase inhibitor.Fórmula:C10H13FN2O5Pureza:98% - 99.79%Forma y color:SolidPeso molecular:260.22RO 2433
CAS:Producto controlado<p>Impurity Sofosbuvir Metabolite GS331007<br>Applications RO 2433 is the deaminated metabolite of β-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine, an effective inhibitor of hepatitis C virus (HCV) replication in vitro.<br>References Asif, G., et. al.: Antimicrob. Agents Ch., 51, 2877 (2007)<br></p>Fórmula:C10H13FN2O5Forma y color:NeatPeso molecular:260.22GS 331007
CAS:<p>Anti-viral; RNA polymerase inhibitor; sofosbuvir metabolite</p>Fórmula:C10H13FN2O5Pureza:Min. 95%Forma y color:Off-White PowderPeso molecular:260.22 g/mol1-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
CAS:Fórmula:C10H13FN2O5Pureza:98%Forma y color:SolidPeso molecular:260.221
