CAS 887781-62-6

MK-0674

CAS: 887781-62-6

MK-0674

Pureza: ≥95%

Peso molecular: 527.5g/mol

Ref: 54-BUP05451

MK-0674

CAS: 887781-62-6

MK-0674 is a synthetic compound with anti-tumor activity. It targets the tumor tissue by inhibiting the production of proteins that are vital for cell division. MK-0674 has been shown to be effective in animal studies and clinical trials, but it is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. MK-0674 has also been found to reduce the levels of collagen and nucleophilic carbonyls in cells exposed to oxidative stress, suggesting that it may have anti-oxidant properties. The drug is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid.

Fórmula: C₂₆H₂₇F₆N₃O₂

Pureza: Min. 95%

Peso molecular: 527.5 g/mol

Ref: 3D-MKB78162

MK-0674

CAS: 887781-62-6

MK-0674 is a cathepsin K inhibitor (IC50: 0.4 nM) that inhibits Cat B, Cat F, Cat L, and Cat S for metabolism-related diseases.

Fórmula: C₂₆H₂₇F₆N₃O₂

Pureza: 97.3% - 99.91%

Forma y color: Solid

Peso molecular: 527.5

Ref: TM-T16089