CAS 888478-45-3

Supinoxin

CAS: 888478-45-3

Supinoxin

Pureza: ≥98%

Peso molecular: 441.46g/mol

Ref: 54-BUP05284

Supinoxin

CAS: 888478-45-3

Supinoxin (RX-5902) is an oral anti-cancer drug targeting p68 RNA helicase, inducing apoptosis in TNBC cells (IC50: 10-20nM).

Fórmula: C₂₂H₂₄FN₅O₄

Pureza: 99.83% - 99.95%

Forma y color: Solid

Peso molecular: 441.46

Ref: TM-T16961

Supinoxin

CAS: 888478-45-3

Supinoxin is a novel anti-cancer drug that inhibits the growth of cancer cells. Supinoxin is a small molecule that selectively inhibits the activity of RNA helicase and blocks the production of mRNAs, leading to cell death. Supinoxin has been shown to inhibit cancerous cell growth in vitro and in vivo. It has also been shown to have a high therapeutic index in mice with implanted human breast cancer xenografts, showing no toxicity at doses up to 10 times higher than the highest tolerated dose. The pharmacokinetics of supinoxin were studied in caco-2 cells and tissues from rats using LC-MS/MS analysis. The terminal half-life was found to be about 20 hours for both rats and humans, which suggests that supinoxin may be suitable for once-daily dosing.

Fórmula: C₂₂H₂₄FN₅O₄

Pureza: Min. 95%

Peso molecular: 441.5 g/mol

Ref: 3D-NKB47845