CAS 9003-11-6

Copolímero de óxido de etileno-óxido de propileno

Descripción:

Copolímero de óxido de etileno-óxido de propileno, identificado por el número CAS 9003-11-6, es un tipo de elastómero termoplástico que exhibe una combinación única de propiedades derivadas de sus monómeros constituyentes. Este copolímero se caracteriza por su flexibilidad, resiliencia y excelente resistencia química, lo que lo hace adecuado para una variedad de aplicaciones, incluyendo adhesivos, selladores y recubrimientos. La estructura consiste en unidades alternas de óxido de etileno y óxido de propileno, que contribuyen a su naturaleza anfifílica, permitiéndole interactuar favorablemente con sustancias tanto polares como no polares. Este copolímero también demuestra buena estabilidad térmica y puede mantener sus propiedades mecánicas en un amplio rango de temperaturas. Además, a menudo se utiliza en formulaciones que requieren baja toxicidad y biocompatibilidad, lo que lo hace adecuado para aplicaciones médicas y relacionadas con alimentos. Su capacidad para formar micelas y emulsiones mejora aún más su utilidad en varios procesos industriales. En general, el Copolímero de óxido de etileno-óxido de propileno es valorado por su versatilidad y rendimiento en diversos entornos químicos.

Fórmula: (C₃H₆O·C₂H₄O)x

InChI: InChI=1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

Clave InChI: InChIKey=RVGRUAULSDPKGF-UHFFFAOYSA-N

SMILES: CC1CO1.C1CO1

Sinónimos:

• 333E
• 50Mb-26X
• 75H380000
• 75H90000
• 75Hb1440
• 80De40U
• Bloatguard
• CE
• Exocorpol
• Kwc-Q
• Magcyl
• Nixolen
• Oxalgon
• PAG
• Poloxalcol
• Poloxalene
• Poloxalkol
• Polyoxyethylene-polyoxypropylene
• Proksanol
• Proxanol
• Regulaid
• Slovanik
• Vepoloxamer
• α-Hydro-ω-hydroxy-poly(oxyethylene)-poly(oxypropylene)
• Glycols, polyethylene-polypropylene
• Oxirane, 2-methyl-, polymer with oxirane
• Oxirane, polymer with methyloxirane
• Oxirane, methyl-, polymer with oxirane

Poloxamer 407

CAS: 9003-11-6

Poloxamer 407 is a chemically stable, biocompatible polymer that is used in a number of medical applications. It has an optimum concentration at between 2 and 5% by weight. Poloxamer 407 has been shown to limit renal injury in animals during ischemia-reperfusion (I/R) injury, as well as reducing the bioavailability of certain drugs. It also exhibits thermoreversible behaviour, which means it can change from a liquid to a gel when heated and back again when cooled. The surface methodology is based on the solvency of the polymer and its ability to form hydrogen bonds with water molecules. Poloxamer 407 has been shown to reduce the thermoresponsiveness of skin grafts in vivo and increase drug absorption through nasal passages, making it suitable for use as a nasal drug delivery system.

Fórmula: (C₃H₆O·C₂H₄O)x

Pureza: Min. 95%

Forma y color: White Powder

Ref: 3D-FP153270

Poloxamer L101, average MW -3800

CAS: 9003-11-6

Pluronic L101 is a non-ionic surfactant. It has shown to be a P-glycoprotein (P-gp) inhibitor, which may be due to its chemical stability and ability to bind to the cell membrane. Pluronic L101 also has been shown to inhibit the growth of skin cancer cells by binding to the cell membrane and preventing the uptake of glycol ethers. The surfactant is also an antimicrobial agent that can inhibit bacteria such as Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. The most common use for this product is in skin care products such as lotions and sunscreens. Pluronic L101 has been shown to have anti-inflammatory properties that are stronger than those of ibuprofen or aspirin when tested on rats with myocardial infarcts. This product is also used in analytical methods for measuring P-gp substrate concentrations in human

Forma y color: Powder

Ref: 3D-FP180036

Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)

CAS: 9003-11-6

Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) is a polymeric drug that has been synthesized to inhibit the activity of P-glycoprotein. This polymer is used to control the uptake of drugs into cells. It also has shown an effect on cancer cell viability, ATP levels, and hydrogen bond formation in vitro. Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) has also been found to be a nonsteroidal anti-inflammatory drug (NSAID). NSAIDs are used for the treatment of pain and inflammation caused by diseases such as osteoarthritis or rheumatoid arthritis. NSAIDs work by inhibiting cyclooxygenase, which is an enzyme that produces prostaglandins from arachidonic acid. The inhibition of prostaglandin synthesis leads to reduced inflammation and pain. NSAIDs can cause side effects

Fórmula: (C₃H₆O•C₂H₄O)x

Pureza: Min. 95%

Forma y color: Solid

Ref: 3D-FP158004

Poloxamer P123

CAS: 9003-11-6

Lubricant in metal working; anti-foaming aid; surface cleanser.  Average MW 5800

Fórmula: (C₃H₆O•C₂H₄O)x

Forma y color: Colorless Powder

Ref: 3D-FP106449

Poloxamer L62

Producto controlado

CAS: 9003-11-6

Pluronic L62 is a surfactant that is used to prevent air bubbles from forming in contact lens solutions. It is composed of synthetic block copolymers, which are a type of polymer with both hydrophobic and hydrophilic segments. Pluronic L62 can be used as an anti-inflammatory agent by inhibiting the production of prostaglandins, which are inflammatory mediators. This drug also has been shown to reduce choroidal neovascularization in mice by inhibiting vascular endothelial growth factor (VEGF). In vivo bioavailability data on pluronic L62 has not yet been published.

Fórmula: (C₃H₆O•C₂H₄O)x

Forma y color: Clear Liquid

Ref: 3D-FP12343