CAS 90098-04-7

Rebamipida

Descripción:

Rebamipida es un compuesto sintético utilizado principalmente en el tratamiento de lesiones y úlceras de la mucosa gástrica. Se clasifica como un agente gastroprotector y es conocido por su capacidad para mejorar los mecanismos de defensa de la mucosa. La estructura química de Rebamipida incluye un moiety de 2-aminobenzotiazol, que contribuye a sus propiedades farmacológicas. Exhibe efectos antiinflamatorios y promueve la síntesis de prostaglandinas, que son cruciales para mantener la integridad de la mucosa gástrica. Además, Rebamipida tiene propiedades antioxidantes, ayudando a neutralizar los radicales libres que pueden dañar los tejidos gástricos. El compuesto se administra típicamente por vía oral y se absorbe bien en el tracto gastrointestinal. Sus efectos terapéuticos se atribuyen a su capacidad para estimular la producción de moco y bicarbonato, protegiendo así el revestimiento gástrico de sustancias nocivas y promoviendo la curación. En general, Rebamipida es reconocido por su papel en la mejora de la defensa de la mucosa gástrica y se utiliza en varios trastornos gastrointestinales.

Fórmula: C₁₉H₁₅ClN₂O₄

InChI: InChI=1/C19H15ClN2O4/c20-13-7-5-11(6-8-13)18(24)22-16(19(25)26)9-12-10-17(23)21-15-4-2-1-3-14(12)15/h1-8,10,16H,9H2,(H,21,23)(H,22,24)(H,25,26)/t16-/m1/s1

Clave InChI: InChIKey=ALLWOAVDORUJLA-UHFFFAOYSA-N

SMILES: C(C(NC(=O)C1=CC=C(Cl)C=C1)C(O)=O)C=2C=3C(NC(=O)C2)=CC=CC3

Sinónimos:

• (+-)-1,2-Dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-4-quinolinepropanoic acid
• +-)-2-(4-Chlorobenzoylamino)-3-(2(1H)-quinolinon-4-yl)propionic acid
• 2-(4-Chloro-benzoylamino)-3-(2-hydroxy-quinolin-4-yl)-propionic acid
• 2-(4-Chloro-benzoylamino)-3-(2-oxo-1,2-dihydro-quinolin-4-yl)-propionic acid
• 2-(4-Chlorobenzoylamino)-3-(1,2-dihydro-2-oxo-4-quinolyl)propionic acid
• 2-[(4-Chlorobenzoyl)amino]-3-(2-oxo-1H-quinolin-4-yl)propanoic acid
• 4-Quinolinepropanoic acid, a-[(4-chlorobenzoyl)amino]-1,2-dihydro-2-oxo-, (R)-
• 4-Quinolinepropanoic acid, a-[(4-chlorobenzoyl)amino]-1,2-dihydro-2-oxo-, (S)-
• 4-Quinolinepropanoic acid, α-[(4-chlorobenzoyl)amino]-1,2-dihydro-2-oxo-
• Mucosta
• N-(4-chlorobenzoyl)-3-(2-oxo-1,2-dihydroquinolin-4-yl)-D-alanine
• N-(4-chlorobenzoyl)-3-(2-oxo-1,2-dihydroquinolin-4-yl)alanine
• Opc 12759
• Proamipide
• Rebator
• α-[(4-Chlorobenzoyl)amino]-1,2-dihydro-2-oxo-4-quinolinepropanoic acid
• Rebamipide
• (+-)-1,2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-4-quinolinepropanoica
• 4-Quinolinepropanoic acid, a-[(4-chlorobenzoyl)amino]-1,2-dihydro-2-oxo-(9CI)
• REBAPIMIDE
• Rebamipid
• 2-(4-Chlorobenzoylamino)-3-(1,2-dihydro-2-oxo-4-
• 2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-(+-)-4-quinolinepropanoicaci
• (+-)-2-(4-chlorobenzoylamino)-3-(2(1h)-quinolinon-4-yl)propionicacid
• 2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-(+-)-4-quinolinepropanoic acid
• 2-(4-CHLOROBENZAMIDO)-3-(2-OXO-1,2-DIHYDROQUINOLIN-4-YL)PROPANOIC ACID
• RebamipideRebamipide
• 1,2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-4-quinolinepropanoicaci(
• opc12759
• REBAMIPIDE,99.5%
• OPC-12759, Mucosta, α-[(4-Chlorobenzoyl)-amino]-1,2-dihydro-2-oxo-4-quinolinepropanoic Acid

2-​(4-​Chloro-​benzoylamino)​-​3-​(2-​hydroxy-​quinolin-​4-​yl)​-​propionic acid

CAS: 90098-04-7

Fórmula: C₁₉H₁₅ClN₂O₄

Pureza: 98%

Forma y color: Solid

Peso molecular: 370.7864

Ref: IN-DA00IMK8

Rebamipide

CAS: 90098-04-7

Rebamipide (OPC12759) is a drug enhancing gastric defense by stimulating COX2, prostaglandins, and mucus, while reducing TNF alpha and free radicals.

Fórmula: C₁₉H₁₅ClN₂O₄

Pureza: 99.48% - 99.61%

Forma y color: White Powder

Peso molecular: 370.79

Ref: TM-T1562

Rebamipide

CAS: 90098-04-7

Rebamipide

Pureza: ≥98%

Peso molecular: 370.79g/mol

Ref: 54-BUP18316

Rebamipide hydrate

CAS: 90098-04-7

Fórmula: C₁₉H₁₅ClN₂O₄·xH₂O

Pureza: ≥ 99.0% (dried basis)

Forma y color: White crystalline powder

Peso molecular: 370.79 (anhydrous)

Ref: 7W-GP6330

Rebamipide

CAS: 90098-04-7

Fórmula: C₁₉H₁₅ClN₂O₄

Forma y color: White To Off-White Solid

Peso molecular: 370.79

Ref: 4Z-R-085005

2-(4-Chlorobenzamido)-3-(2-Oxo-1,2-Dihydroquinolin-4-Yl)Propanoic Acid

CAS: 90098-04-7

2-(4-Chlorobenzamido)-3-(2-Oxo-1,2-Dihydroquinolin-4-Yl)Propanoic Acid

Pureza: 98%

Peso molecular: 370.79g/mol

Ref: 54-OR1009762

Rebamipide

CAS: 90098-04-7

Fórmula: C₁₉H₁₅ClN₂O₄

Pureza: >98.0%(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 370.79

Ref: 3B-R0085

2-(4-CHLOROBENZOYLAMINO)-3-(1,2-DIHYDRO-2-OXO-4-QUINOLYL)PROPIONIC ACID

CAS: 90098-04-7

Pureza: 95.0%

Forma y color: Solid

Peso molecular: 370.7900085449219

Ref: 10-F300998

Rebamipide

Producto controlado

CAS: 90098-04-7

Applications Shows antiulcer activity in rats.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Uchida, M., et al.: Chem. Pharm. Bull., 33, 3775 (1985), Yamasaki, K., et al.: Eur. J. Pharmacol., 142, 23 (1987),

Fórmula: C₁₉H₁₅ClN₂O₄

Forma y color: Off-White

Peso molecular: 370.79

Ref: TR-R139000

Rebamipide - Bio-X ™

CAS: 90098-04-7

Rebamipide is a gastroprotective agent that is used to treat various gastrointestinal disorders such as gastric ulcers and GERD. This drug’s mechanism of action is not fully understood however, it is thought to exert its effects by promoting the secretion of protective mucus in the stomach and intestine, which helps to create a barrier against stomach acid and other irritants. Additionally, it has antioxidant and anti-inflammatory properties that can help reduce tissue damage.

Fórmula: C₁₉H₁₅ClN₂O₄

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 370.79 g/mol

Ref: 3D-BC164330

Rebamipide

CAS: 90098-04-7

COX-2 positive regulator; gastroprotective; anti-inflammatory; anti-ulcer agent

Fórmula: C₁₉H₁₅ClN₂O₄

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 370.79 g/mol

Ref: 3D-FC15908