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CAS 90357-51-0
:N-[4-Ciano-3-(trifluorometil)fenil]-2-metil-2-oxiranocarboxamida
Descripción:
N-[4-Ciano-3-(trifluorometil)fenil]-2-metil-2-oxiranocarboxamida, con el número CAS 90357-51-0, es un compuesto químico caracterizado por su estructura única, que incluye un grupo funcional epóxido (oxirano) y un grupo ciano unido a un anillo fenílico. La presencia de un grupo trifluorometilo mejora su estabilidad química y lipofilia, lo que lo hace potencialmente útil en diversas aplicaciones, incluyendo productos farmacéuticos y agroquímicos. La funcionalidad epóxica del compuesto sugiere que puede participar en reacciones de apertura de anillo, lo que puede llevar a la formación de diversos derivados. Además, el grupo ciano puede contribuir a la reactividad y polaridad del compuesto, influyendo en su solubilidad e interacción con sistemas biológicos. En general, las características distintivas de este compuesto lo convierten en un tema de interés en la química sintética y la ciencia de materiales, aunque las aplicaciones específicas dependerían de investigaciones adicionales sobre sus propiedades y comportamiento en diferentes entornos.
Fórmula:C12H9F3N2O2
InChI:InChI=1S/C12H9F3N2O2/c1-11(6-19-11)10(18)17-8-3-2-7(5-16)9(4-8)12(13,14)15/h2-4H,6H2,1H3,(H,17,18)
Clave InChI:InChIKey=UQUQTWDUTIAAAY-UHFFFAOYSA-N
SMILES:C(NC1=CC(C(F)(F)F)=C(C#N)C=C1)(=O)C2(C)CO2
Sinónimos:- 1,2-Epoxy-2-Methyl-N-[4-Cyano-3-(Trifluoromethyl)]
- 1,2-Epoxy-2-Methyl-N[4-Cyano-3(Trifluoromethyl)-Phenyl]Propanamide
- 2-Methyl-oxirane-2-carboxylic acid (4-cyano-3-trifluoromethylphenyl)-amide
- 2-Methyloxirane-2-carboxylic acid N-(4-cyano-3-trifluoromethylphenyl)amide
- 2-Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-
- 4'-Cyano-3'-trifluoromethyl-2,3-epoxy-2-methylpropioanilide
- Carboxamide
- N-[4-Cyano-3-(Triflouromethyl)Phenyl]-2-Methyl-2-Oxirane Carboxamide
- N-[4-Cyano-3-(Trifluoromethyl)Phenyl]Methacrylamide Epoxide
- N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide
- N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-oxiranecarboxamide
- N-[4-Cyano-3-(trifluoromethyl)phenyl]-methacrylamide exoxide
- N-[4-Cyano-3-Trifluoromethy Phenyl]-2-Oxirane Carboxamide
- N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-oxiranecarboxamide
- N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
- Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-
- Phenyl]-2-methyl-2-oxirane
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Encontrado 9 productos.
Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-
CAS:Fórmula:C12H9F3N2O2Pureza:98%Forma y color:SolidPeso molecular:270.2073Bicalutamide Impurity 3 (Bicalutamide Epoxide Impurity)
CAS:Fórmula:C12H9F3N2O2Forma y color:White To Off-White SolidPeso molecular:270.21N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide
CAS:N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamidePureza:98%Peso molecular:270.21g/mol1,2-Epoxy-2-methyl-N-[4-cyano-3-(trifluoromethyl)-phenyl]propionamide
CAS:Producto controladoFórmula:C12H9F3N2O2Forma y color:NeatPeso molecular:270.21N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
CAS:Fórmula:C12H9F3N2O2Pureza:>95.0%(GC)Forma y color:White to Almost white powder to crystalPeso molecular:270.21N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide
CAS:Producto controladoImpurity Bicalutamide Oxirane Impurity / Bicalutamide Epoxide Impurity
Applications N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide, is an intermediate in synthesis of more complex pharmaceutical compounds. It is used in the synthesis of potential impurities of Bicalutamide (B382000), which is an oral nonsteroidal, anti-androgen drug used for prostate cancer.
References Nandu Baban, B., et al.: Synthetic Communications, 39, 1516 (2009);Fórmula:C12H9F3N2O2Forma y color:NeatPeso molecular:270.21N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide
CAS:Fórmula:C12H9F3N2O2Pureza:98%Forma y color:SolidPeso molecular:270.211N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
CAS:N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide (NUOX) is a potential anticancer agent that has been shown to have an acidic pKa of 5.8 and to be active against cancer cells in the same way as bicalutamide, which is a known antiandrogen. NUOX has been shown to increase the number of cavities in polybenzimidazole (PBI) films by enhancing the rate of oxidation. NUOX also inhibits the growth of human cancer cells by binding sulfide groups on proteins and DNA, inhibiting cellular respiration. NUOX is not water soluble, so it must be dissolved in solvents such as acetonitrile or chloroform before administration.Fórmula:C12H9F3N2O2Pureza:Min. 95%Forma y color:White PowderPeso molecular:270.21 g/mol
![Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00IG48.jpg&w=3840&q=75)
![1,2-Epoxy-2-methyl-N-[4-cyano-3-(trifluoromethyl)-phenyl]propionamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F86%2Fthumb%2FMM0894.11.jpg&w=3840&q=75)
![N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3B%2Fthumb%2FC3607.jpg&w=3840&q=75)
![N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb%2FC987585.jpg&w=3840&q=75)
![N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb%2FIC58274.jpg&w=3840&q=75)
