CAS 9041-93-4

Sulfato de bleomicina

Descripción:

Sulfato de bleomicina es un antibiótico glicopéptido derivado de la bacteria Streptomyces verticillus. Se utiliza principalmente en la quimioterapia del cáncer, particularmente para tratar el cáncer testicular, el linfoma de Hodgkin y ciertos tipos de carcinomas de células escamosas. El compuesto exhibe un mecanismo de acción único al inducir rupturas en las cadenas de ADN, lo que lleva a la inhibición de la síntesis de ADN y, en última instancia, desencadena la apoptosis en las células cancerosas. La bleomicina es conocida por sus efectos mielosupresores relativamente bajos en comparación con otros agentes quimioterapéuticos, lo que la convierte en una opción valiosa en terapias combinadas. Sin embargo, puede causar toxicidades dependientes de la dosis, particularmente toxicidad pulmonar, lo que requiere un monitoreo cuidadoso durante el tratamiento. La forma sulfato mejora su solubilidad y estabilidad, facilitando su uso en entornos clínicos. La bleomicina se administra típicamente por inyección, y su eficacia puede verse influenciada por factores como el tipo de tumor y la presencia de mecanismos de resistencia específicos en las células cancerosas. En general, Sulfato de bleomicina sigue siendo un agente importante en oncología, con investigaciones en curso que exploran su potencial en varios contextos terapéuticos.

Fórmula: C₁₁₀H₁₆₈N₃₄O₄₆S₇

InChI: InChI=1/C52H77N13O19S3/c1-7-11-54-18-32-56-13-9-26(62-32)45(75)65-35(41(27-16-55-22-60-27)82-51-43(39(72)37(70)29(19-66)81-51)83-50-40(73)42(84-52(53)79)38(71)30(20-67)80-50)48(78)61-24(3)36(69)23(2)44(74)64-34(25(4)68)47(77)58-14-10-33-63-28(21-85-33)49-59-17-31(86-49)46(76)57-12-8-15-87(5)6/h9,13,16-17,21-25,29-30,34-43,50-51,54,66-73H,7-8,10-12,14-15,18-20H2,1-6H3,(H7-,53,55,57,58,60,61,64,65,74,75,76,77,78,79)/p+1/t23-,24+,25?,29+,30+,34?,35+,36-,37+,38-,39+,40-,41+,42+,43-,50-,51+/m0/s1

Sinónimos:

• 3-[[2-[2-[2-[[2-[[(2S,3S,4R)-4-[[(2R,3S)-3-[(2S,3S,4R,5S,6R)-3-[(2S,3S,4R,5S,6R)-4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-3-(1H-imidazol-4-yl)-2-[[2-(propylaminomethyl)pyrimidine-4-carbonyl]amino]propanoyl]amino]-3-hydroxy-2-methyl-pentanoyl]amino]-3-hydroxy-butanoyl]amino]ethyl]thiazol-4-yl]thiazole-5-carbonyl]amino]propyl-dimethyl-sulfonium
• Blenoxane
• Bleomycin Sulfate From Streptomyces Verticillus
• Bleomycin, sulfate (salt)
• Bleomycine Sulfate
• Blexane
• Bleomycin sulfate
• BLEOMYCIN SULFATE, STREPTOMYCES VERTICILLUS
• BLEOMYCIN SULFATE FROM STREPTOMYCES VERTICILLUS 0 TO 5 °C
• BLEOMYCIN SULFATE FROM STREPTOMYCES VERT ICILLUS, LYOPH.
• Blenoxane, Bleo, Blexane
• BLEO
• 3-[[2-[2-[2-[2-[4-[2-[6-Amino-2-[1-(2-amino-2-carbamoyl-ethyl)amino-2-carbamoyl-ethyl]-5-methyl-pyrimidin-4-yl]carbonylamino-3-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-3-(3H-imidazol-4-yl)propanoyl]amino-3-hydroxy-2-methyl-pentanoyl]amino-3-hydroxy-butanoyl]aminoethyl]-1,3-thiazol-4-yl]-1,3-thiazol-4-yl]carbonylamino]propyl-dimethyl-sulfonium hydrogen sulfate
• BLEMOYCIN SULFATE
• BLEOMYCIN SULFATE CELL CULTURE TESTED
• BLEOMYCIN SULPHATE
• Bleomycin Sulfate, Blenoxane
• Blenmycins
• Bleomycin Sulfate (A mixture of bleomycin sulfate salts)
• BLEOMYCIN SULFATE, BPC
• NSC-125066

Bleomycin Sulfate (mixture)

CAS: 11056-06-7, 9041-93-4

Pureza: >85.0%(HPLC)

Forma y color: White to Light yellow powder to crystal

Ref: 3B-B3972

Bleomycin sulfate

CAS: 9041-93-4

Bleomycin sulfate, 9041-93-4, is a glycopeptide antibiotic isolated from Streptomyces verticillus which has antineoplastic properties. Learn more at Thermo Fisher Scientific.

Fórmula: C₅₅H₈₅N₁₇O₂₅S₄

Peso molecular: 1512.62

Ref: 02-J60727

Bleomycin sulfate, Cell Culture Grade

CAS: 9041-93-4

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Fórmula: C₅₅H₈₅N₁₇O₂₅S₄

Forma y color: White to pale cream to pale yellow, Powder

Peso molecular: 1512.62

Ref: 02-J67560

BLEOMYCIN SULFATE CRS

CAS: 9041-93-4

BLEOMYCIN SULFATE CRS

Fórmula: C₅₅H₈₄N₁₇O₂₁S₃

Forma y color: White. Light Yellow. Powder.

Peso molecular: 1415.551

Ref: 41-B1141000

Bleomycin sulfate

CAS: 9041-93-4

Bleomycin sulfate

Fórmula: C₅₅H₈₄N₁₇O₂₁S₃

Forma y color: White

Peso molecular: 1415.551

Ref: 47-971

SECOND INTERNATIONAL STANDARD FOR BLEOMYCIN COMPLEX A2/B2

CAS: 9041-93-4

SECOND INTERNATIONAL STANDARD FOR BLEOMYCIN COMPLEX A2/B2

Fórmula: C₅₅H₈₄N₁₇O₂₁S₃

Peso molecular: 1415.551

Ref: 41-ISA46290

Bleomycin Sulfate

CAS: 9041-93-4

Antibiotics nesoi

Fórmula: NA(Mixture)

Forma y color: Cream Powder

Peso molecular: 1415.551

Ref: 45-1076308

Bleomycin (sulfate)

CAS: 9041-93-4

Fórmula: C₅₅H₈₅N₁₇O₂₅S₄

Forma y color: Solid

Peso molecular: 1512.6223

Ref: IN-DA003913

Bleomycin sulfate, low endotoxin

CAS: 9041-93-4

Fórmula: C₅₅H₈₅N₁₇O₂₅S₄

Pureza: ≥ 90% (A2+B2)

Forma y color: White to off-white crystalline powder

Peso molecular: 1512.62

Ref: 7W-GP3271

Bleomycin sulphate

CAS: 9041-93-4

Bleomycin sulphate

Fórmula: C₅₅H₈₅N₁₇O₂₅S₄

Pureza: By hplc: bleomycin a2: 68.19% (Typical Value in Batch COA)

Forma y color: white powder

Peso molecular: 2,927.17g/mol

Ref: 54-BI3543

Bleomycin sulfate

CAS: 9041-93-4

Fórmula: C₅₅H₈₅N₁₇O₂₅S₄

Pureza: ≥ 90% (A2+B2, anhydrous basis)

Forma y color: White to off-white crystalline powder

Peso molecular: 1512.62

Ref: 7W-GA7621

Bleomycin Sulfate

CAS: 9041-93-4

Fórmula: C₅₅H₈₄N₂₀O₂₁S₂·H₂SO₄C₅₅H₈₄N₁₇O₂₁S₃·H₂SO₄

Forma y color: White To Off-White Solid

Peso molecular: 1415.55 98.07; 1425.52 98.07

Ref: 4Z-B-190006

Bleomycin Sulfate

CAS: 9041-93-4

Bleomycin Sulfate (Blenoxane) is a glycopeptide antibiotic, an inhibitor of DNA synthesis.

Fórmula: C₅₅H₈₅N₁₇O₂₅S₄

Pureza: 98% - ≥98%

Forma y color: Less Or Yellowish Powder Possible Bluish Color Depending On Copper Content (Ntp 1992)

Peso molecular: 1523 (average)

Ref: TM-T6116

Bleomycin sulfate - mixture of Bleomycin A2, B2

CAS: 9041-93-4

Inducer of DNA strand breaks; glycopeptide antibiotic, anti-neoplastic

Fórmula: C₅₅H₈₄N₁₇O₂₁S₃·xH₂SO₄

Pureza: Min. 77 Area-%

Forma y color: Powder

Peso molecular: 1,415.56 g/mol

Ref: 3D-AB15942

Bleomycin Sulfate (BLM-S), 90%

CAS: 9041-93-4

Pureza: min. 90%

Forma y color: White to off - white, Powder

Ref: SR-20899