CAS 918633-87-1: (1-Methyl-2-nitro-1H-imidazol-5-yl)methyl N,N′-bis(2-bromoethyl)phosphorodiamidate

Fórmula: C₉H₁₆Br₂N₅O₄P

InChI: InChI=1S/C9H16Br2N5O4P/c1-15-8(6-12-9(15)16(17)18)7-20-21(19,13-4-2-10)14-5-3-11/h6H,2-5,7H2,1H3,(H2,13,14,19)

Clave InChI: InChIKey=UGJWRPJDTDGERK-UHFFFAOYSA-N

SMILES: O=N(=O)C1=NC=C(N1C)COP(=O)(NCCBr)NCCBr

Sinónimos:

• Phosphorodiamidic acid, N,N′-bis(2-bromoethyl)-, (1-methyl-2-nitro-1H-imidazol-5-yl)methyl ester
• TH 302
• Evofosfamide
• (1-Methyl-2-nitro-1H-imidazol-5-yl)methyl N,N′-bis(2-bromoethyl)phosphorodiamidate
• 2-Bromo-N-[(2-bromoethylamino)-[(3-methyl-2-nitroimidazol-4-yl)methoxy]phosphoryl]ethanamine

Evofosfamide

CAS: 918633-87-1

Evofosfamide (TH-302) is a hypoxia-activated prodrug that releases Br-IPM in tumors to cause DNA damage …

• Fórmula: C₉H₁₆Br₂N₅O₄P
• Pureza: 98.74% - 99.75%
• Forma y color: Solid
• Peso molecular: 449.04

TH-302

CAS: 918633-87-1

Applications TH-302 is a 2-nitroimidazole triggered hypoxia-activated prodrug (HAP) of bromo-isophosphoramide mustard. Studies have shown …

• Fórmula: C₉H₁₆Br₂N₅O₄P
• Forma y color: Neat
• Peso molecular: 449.04

(1-Methyl-2-nitro-1H-imidazol-5-yl)methyl N,N'-bis(2-bromoethyl)phosphorodiamidate

CAS: 918633-87-1

Th-302 is a phosphorodiamidate prodrug that is converted to methyl N,N'-bis(2-bromoethyl)phosphorodiamidate (th-302) in the body. …

• Fórmula: C₉H₁₆Br₂N₅O₄P
• Pureza: Min. 95%
• Peso molecular: 449.04 g/mol