CAS 92823-03-5

Flomoxef sódico

Descripción:

Flomoxef sódico es un antibiótico cefalosporínico de amplio espectro, utilizado principalmente por sus propiedades antibacterianas. Es efectivo contra una variedad de bacterias Gram-positivas y Gram-negativas, lo que lo hace útil en el tratamiento de infecciones causadas por estos patógenos. El compuesto se caracteriza por su capacidad para resistir la hidrólisis por ciertas beta-lactamasas, lo que mejora su eficacia contra cepas bacterianas resistentes. Flomoxef sódico se administra típicamente por inyección y es conocido por su perfil de toxicidad relativamente bajo. Su farmacocinética incluye una buena penetración en los tejidos y una vida media favorable, lo que permite regímenes de dosificación efectivos. La sustancia se utiliza a menudo en entornos clínicos para tratar infecciones del tracto respiratorio, infecciones del tracto urinario e infecciones cutáneas. Al igual que con cualquier antibiótico, el potencial de desarrollo de resistencia requiere una cuidadosa consideración de su uso, y es importante seguir las pautas para una prescripción adecuada para mitigar este riesgo. En general, Flomoxef sódico representa una opción valiosa en el arsenal de terapias antimicrobianas.

Fórmula: C₁₅H₁₈F₂N₆O₇S₂·Na

InChI: InChI=1S/C15H18F2N6O7S2.Na/c1-29-15(18-8(25)6-31-13(16)17)11(28)23-9(10(26)27)7(4-30-12(15)23)5-32-14-19-20-21-22(14)2-3-24;/h12-13,24H,2-6H2,1H3,(H,18,25)(H,26,27);/t12-,15+;/m1./s1

Clave InChI: InChIKey=SYHZUFMYQQRMKT-YLCXCWDSSA-N

SMILES: N(C(CSC(F)F)=O)[C@@]1(OC)[C@@]2(N(C1=O)C(C(O)=O)=C(CSC=3N(CCO)N=NN3)CO2)[H].[Na]

Sinónimos:

• 5-Oxa-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((((difluoromethyl)thio)acetyl)amino)-3-(((1-(2-hydroxyethyl)-1H-tetrazol-5-yl)thio)methyl)-7-methoxy-8-oxo-, monosodium salt, cis-
• 5-Oxa-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(2-((difluoromethyl)thio)acetamido)-3-(((1-(2-hydroxyethyl)-1H-tetrazol-5-yl)thio)methyl)-7-methoxy-8-oxo-, sodium salt,(6R,7R)-
• 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-, monosodium salt, (6R,7R)-
• 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-, monosodium salt, (6R-cis)-
• 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(difluoromethyl)thio]acetyl]amino]-3-[[[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]thio]methyl]-7-methoxy-8-oxo-, sodium salt (1:1), (6R,7R)-
• 6315 S Shionogi
• 6315S
• Flomoxef sodium salt
• Flumarin
• sodium (6R,7R)-7-({[(difluoromethyl)sulfanyl]acetyl}amino)-3-({[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Flomoxef sodium

CAS: 92823-03-5

Fórmula: C₁₅H₁₇F₂N₆NaO₇S₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 518.4481

Ref: IN-DA00GRA2

Flomoxef Sodium Salt

CAS: 92823-03-5

Fórmula: C₁₅H₁₇F₂N₆O₇S₂·Na

Forma y color: White To Off-White Solid

Peso molecular: 495.45 22.99

Ref: 4Z-F-107001

Flomoxef Sodium

Producto controlado

CAS: 92823-03-5

Stability Hygroscopic
Applications Flomoxef Sodium is a sodium salt derivative of Flomoxef (F401850); an oxacephem derived beta-lactam antibiotic that is particularly effective against gram-positive bacteria.
References Miwa, H. et al.: Chemotherapy, 35, 121 (1987); Mikamo, H. et al.: Curr. Therap. Res., 56, 873 (1995);

Fórmula: C₁₅H₁₇F₂N₆NaO₇S₂

Forma y color: Neat

Peso molecular: 518.45

Ref: TR-F403000

Flomoxef Sodium - Bio-X ™

CAS: 92823-03-5

Flomoxef sodium is a water-soluble second/fourth-generation cephalosporin, Shionogi β-lactam antibiotic. Flomoxef inhibits bacterial growth through inhibition of cell wall biosynthesis. It has been shown to be effective against infections caused by Streptococcus pneumoniae, Enterobacter aerogenes, and Acinetobacter baumannii among other bacteria, and can be used to treat ongoing infections or as a prophylactic for example ahead of surgery. Flomoxef sodium has been shown to have synergistic effects when used in combination with isepamicin sulfate and penicillin, which may be due to its ability to increase the permeability of the bacterial cell membrane. Clinical trials are currently underway for flomoxef sodium as a treatment for MRSA infections and UTIs. 
Flomoxef Sodium is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Fórmula: C₁₅H₁₈F₂N₆O₇S₂•Na

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 519.46 g/mol

Ref: 3D-BF300080

Flomoxef Sodium

CAS: 92823-03-5

Flomoxef sodium is a water-soluble prodrug with antibacterial activity that is converted to the active form, flomoxef. Flomoxef sodium inhibits bacterial growth by binding to penicillin-binding proteins and inhibiting cell wall synthesis. It has been shown to be effective against infections caused by Streptococcus pneumoniae, Enterobacter aerogenes, and Acinetobacter baumannii. Flomoxef sodium has been shown to have synergistic effects when used in combination with isepamicin sulfate and penicillin, which may be due to its ability to increase the permeability of the bacterial cell membrane. Clinical trials are currently underway for flomoxef sodium as a treatment for MRSA infections.

Fórmula: C₁₅H₁₇F₂N₆NaO₇S₂

Forma y color: White Powder

Peso molecular: 518.45 g/mol

Ref: 3D-FF41634

Flomoxef sodium

CAS: 92823-03-5

Flomoxef sodium, an antibiotic belonging to the oxacephem group, exhibits excellent activity against a broad spectrum of Gram-positive bacteria.

Fórmula: C₁₅H₁₇F₂N₆NaO₇S₂

Pureza: 99.28%

Forma y color: Solid

Peso molecular: 518.44

Ref: TM-T11301L

Flomoxef Sodium Salt

CAS: 92823-03-5

Fórmula: C₁₅H₁₇F₂N₆O₇S₂Na

Peso molecular: 495.45 : 23.0

Ref: ST-EA-CP-F143003