CAS 936481-23-1

(2'R)-N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine

Producto controlado

CAS: 936481-23-1

Applications (2'R)-N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine is an epimer of N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine (D199035), which is an active metabolite of Maytansine (M197940), inhibits in vitro polymerization of tubulin and is used in the treatment of advanced breast cancer.
References Remillard, S., et. al.: Science, 189, 1002 (1975); Prota, A.E., et. al.: P. Natl. Acad. Sci. USA, 111, 13817 (2014);

Fórmula: C₃₆H₅₀ClN₃O₁₀S

Forma y color: White

Peso molecular: 752.31

Ref: TR-D199038