![(2E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F29681-2e-3-3-4-fluorophenyl-1-1-methylethyl-1h-indol-2-yl-2-propenal.webp&w=3840&q=75)
CAS 93957-50-7
:(2E)-3-[3-(4-fluorofenil)-1-(1-metiletil)-1H-indol-2-il]-2-propenal
Descripción:
La sustancia química conocida como (2E)-3-[3-(4-fluorofenil)-1-(1-metiletil)-1H-indol-2-il]-2-propenal, con número CAS 93957-50-7, se caracteriza por su estructura compleja, que incluye un moiety de indol y un grupo funcional propenal. Este compuesto presenta un grupo fluorofenilo, que contribuye a su potencial actividad biológica y lipofilia. La presencia del grupo isopropilo en el anillo de indol mejora sus propiedades estéricas, posiblemente influyendo en sus interacciones con objetivos biológicos. La parte propenal de la molécula indica que puede participar en varias reacciones químicas, incluidas adiciones de Michael o adiciones conjugadas, debido a la presencia del sistema carbonilo α,β-insaturado. Este compuesto puede exhibir propiedades farmacológicas interesantes, convirtiéndolo en un tema de interés en química medicinal y desarrollo de fármacos. Sus características específicas, como solubilidad, estabilidad y reactividad, dependerían de las condiciones circundantes y de la presencia de otros grupos funcionales en un entorno dado.
Fórmula:C20H18FNO
InChI:InChI=1S/C20H18FNO/c1-14(2)22-18-7-4-3-6-17(18)20(19(22)8-5-13-23)15-9-11-16(21)12-10-15/h3-14H,1-2H3/b8-5+
Clave InChI:InChIKey=DVWHSTKQJBIYCK-VMPITWQZSA-N
SMILES:C(=C/C=O)\C1=C(C=2C(N1C(C)C)=CC=CC2)C3=CC=C(F)C=C3
Sinónimos:- (2E)-3-[3-(4-Fluorophenyl)-1-(1-Methylethyl)-1H-Indol-2-Yl]-2-Propenal
- (E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde
- (E)-3-[3'-(4''-Fluorophenyl)-1'-(1''-Methylethyl)-1H-Indol-2''-Yl]-2-Propnal
- (E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal
- (E)-3-[3-(4-fluorophenyl)-1-(1-methylethyl)-2-indolyl]propenal
- 2-Propenal, 3-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-, (2E)-
- 2-Propenal,3-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-, (E)-
- Fluvastatin intermediate
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Encontrado 9 productos.
(E)-3-[3-(4-Fluorophenyl)-1-isopropylindol-2-yl]acrolein
CAS:Fórmula:C20H18FNOPureza:>98.0%(GC)Forma y color:Light orange to Yellow to Green powder to crystalPeso molecular:307.372-Propenal, 3-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-, (2E)-
CAS:Fórmula:C20H18FNOPureza:98%Forma y color:SolidPeso molecular:307.3614(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde
CAS:(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehydePureza:98%Peso molecular:307.37g/mol(E)-3-[3'-(4''-fluorophenyl)-1'-(1''-methylethyl)-1H-indol-2''-yl]-2-propnal
CAS:(E)-3-[3'-(4''-Fluorophenyl)-1'-(1''-methylethyl)-1H-indol-2''-yl]-2-propnal is an amoebicidal agent that belongs to the class of indole derivatives. It has been shown to inhibit tumor growth in animal models, and thus may be a potential anti-cancer drug. The activity index of (E)-3-[3'-(4''-fluorophenyl)-1'-(1''-methylethyl)-1H-indol-2''-yl]-2-propnal was significantly lower than those of fenoldopam, a well known antihypertensive agent, for the treatment of liver cancer. The compound also inhibits the growth of bacteria by inhibiting protein synthesis in organisms such as amoeba.Fórmula:C20H18FNOPureza:Min. 95%Forma y color:Yellow PowderPeso molecular:307.36 g/mol(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde-d7
CAS:Producto controladoApplications (E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde-d7 an isotope labelled reactant used in the synthesis of Fluvastatin (F601250), a synthetic HMG-CoA reductase inhibitor.
References Sacharia, J.R., et. al.: J. Org. Chem., 75, 7514 (2010); Kim, A., Kim, I.S.: Bull. Korean Chem. Soc., 32, 3748 (2011); Yuan, J., et al.: Atherosclerosis, 87, 147 (1991); Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992); Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993)Fórmula:C20D7H11FNOForma y color:NeatPeso molecular:314.405(E)-3-[3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl]-propenal
CAS:Fórmula:C20H18FNOPureza:98%Forma y color:SolidPeso molecular:307.368(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde
CAS:Producto controladoFórmula:C20H18FNOForma y color:NeatPeso molecular:307.36
![(E)-3-[3-(4-Fluorophenyl)-1-isopropylindol-2-yl]acrolein](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3B%2Fthumb%2FF0819.jpg&w=3840&q=75)
![2-Propenal, 3-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-, (2E)-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA003C0F.jpg&w=3840&q=75)
![(E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]prop-2-enal](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F86%2Fthumb%2FMM0676.14-0025.jpg&w=3840&q=75)
![(E)-3-[3'-(4''-fluorophenyl)-1'-(1''-methylethyl)-1H-indol-2''-yl]-2-propnal](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb%2FFF37514.jpg&w=3840&q=75)
![(E)-3-[3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl]-propenal](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF036562.jpg&w=3840&q=75)
