CAS 93957-55-2
:Fluvastatina sódica
Descripción:
Fluvastatina sódica es un agente sintético para reducir lípidos que pertenece a la clase de las estatinas, utilizado principalmente para manejar la hiperlipidemia y reducir el riesgo de enfermedades cardiovasculares. Funciona como un inhibidor de la HMG-CoA reductasa, que juega un papel crucial en la biosíntesis del colesterol. El compuesto se caracteriza por su capacidad para reducir los niveles de colesterol de lipoproteínas de baja densidad (LDL) mientras aumenta modestamente el colesterol de lipoproteínas de alta densidad (HDL). Fluvastatina sódica se administra típicamente por vía oral y se absorbe bien en el tracto gastrointestinal, aunque su biodisponibilidad se ve afectada por el metabolismo de primer paso en el hígado. El fármaco generalmente es bien tolerado, pero los efectos secundarios potenciales pueden incluir dolor muscular, anormalidades en las enzimas hepáticas y trastornos gastrointestinales. Está contraindicado en pacientes con enfermedad hepática activa o en aquellos que están embarazadas o amamantando. Fluvastatina sódica a menudo se prescribe junto con modificaciones dietéticas y cambios en el estilo de vida para mejorar su eficacia en el manejo del colesterol. Se recomienda un monitoreo regular de los niveles de lípidos y pruebas de función hepática durante el tratamiento.
Fórmula:C24H26FNO4·Na
InChI:InChI=1/C24H26FNO4.Na/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30;/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30);/b12-11+;/t18-,19-;/s2
Clave InChI:InChIKey=CUOKYGJQSIKNFS-ZADPHQEYNA-N
SMILES:C(=C/[C@@H](C[C@@H](CC(O)=O)O)O)\C1=C(C=2C(N1C(C)C)=CC=CC2)C3=CC=C(F)C=C3.[Na]
Sinónimos:- (3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid monosodium salt
- 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, monosodium salt, (3R,5S,6E)-rel-
- 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, monosodium salt, [R*,S*-(E)]-(±)-
- 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, sodium salt (1:1), (3R,5S,6E)-rel-
- Almastatin
- Canef
- Cranoc
- Fluindostatin
- Fluvastatin Sodium Salt
- Fractal
- Lescol
- Lescol XL
- Lochol
- Locol
- Sodium (3R,5S,6E)-7-[3-(4-Fluorophenyl)-1-(1-Methylethyl)-1H-Indol-2-Yl]-3,5-Dihydroxy-6-Heptenoate
- Vastin
- Xu 62-320
- sodium (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate
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Encontrado 19 productos.
Fluvastatin Sodium Salt
CAS:Fórmula:C24H25FNNaO4Pureza:>98.0%(HPLC)(N)Forma y color:Light orange to Yellow to Green powder to crystalPeso molecular:433.46FLUVASTATIN SODIUM CRS
CAS:FLUVASTATIN SODIUM CRSFórmula:C24H25FNNaO4Forma y color:White. Orange. Light Yellow. Powder.Peso molecular:433.4478FLUVASTATIN FOR SYSTEM SUITABILITY CRS
CAS:FLUVASTATIN FOR SYSTEM SUITABILITY CRSFórmula:C24H25FNNaO4Peso molecular:433.4478Fluvastatin sodium
CAS:Fluvastatin sodiumFórmula:C24H25NNaO4Pureza:97.4%Forma y color:Light Yellow. To. OrangePeso molecular:414.16813Fluvastatin Sodium
CAS:Cardiovascular drugs, not elsewhere specified or includedFórmula:C24H25FNNaO4Forma y color:White Yellow PowderPeso molecular:433.16653sodium (3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoate
CAS:Fórmula:C24H25FNNaO4Pureza:98%Forma y color:SolidPeso molecular:433.4478Fluvastatin sodium
CAS:Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterolFórmula:C24H25FNNaO4Pureza:98.54% - 99.56%Forma y color:Light Yellow Solid PowderPeso molecular:433.45Fluvastatin Sodium Salt
CAS:Fórmula:C24H25FNO4·NaForma y color:Yellow SolidPeso molecular:410.47 22.99Fluvastatin-d6 Sodium Salt
CAS:Fórmula:C24H19D6FNO4·NaForma y color:Off-White SolidPeso molecular:416.50 22.99Fluvastatin sodium salt
CAS:Fórmula:C24H25FNO4·Na·xH2OPureza:98.0 - 102.0 % (anhydrous basis)Forma y color:Off-white to pale yellow or light yellow-orange powderPeso molecular:433.45 (anhydrous)Fluvastatin sodium
CAS:Producto controladoFórmula:C24H25FNO4·NaForma y color:NeatPeso molecular:433.45Fluvastatin Sodium Salt (Relative Stereochemistry)
CAS:Stability Hygroscopic
Applications A synthetic HMG-CoA reductase inhibitor. Antilipemic.
References Yuan, J., et al.: Atherosclerosis, 87, 147 (1991), Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992), Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993);Fórmula:C24H25FNO4·NaForma y color:NeatPeso molecular:433.45Fluvastatin-d6 Sodium
CAS:Producto controladoApplications Fluvastatin-d6 Sodium Salt is the labeled analogue of Fluvastatin Sodium Salt (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic.
References Yuan, J., et al.: Atherosclerosis, 87, 147 (1991), Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992), Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993);Fórmula:C24H19D6FNNaO4Forma y color:NeatPeso molecular:439.48Fluvastatin sodium
CAS:Fluvastatin is a statin that lowers blood cholesterol and triglycerides by inhibiting HMG-CoA reductase, an enzyme that plays a critical role in the synthesis of cholesterol. Fluvastatin has also been shown to reduce the incidence of myocardial infarction, and to reduce atherosclerotic lesions in animal models, reducing the incidence of cardiovascular disease. Fluvastatin also has been shown to inhibit the activation of toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS), which may be related to its anti-inflammatory effects. Furthermore, through lowering blood cholesterol, Fluvastatin also inhibits tubulointerstitial injury and prevents renal damage caused by high concentrations of the lipid.
Fórmula:C24H25FNNaO4Pureza:Min. 98%Forma y color:Off-White PowderPeso molecular:433.45 g/molFluvastatin sodium salt - Bio-X ™
CAS:Fluvastatin is a statin that lowers blood cholesterol and triglycerides by inhibiting HMG-CoA reductase, an enzyme that plays a critical role in the synthesis of cholesterol. Fluvastatin has also been shown to reduce the incidence of myocardial infarction, and to reduce atherosclerotic lesions in animal models, reducing the incidence of cardiovascular disease. Fluvastatin also has been shown to inhibit the activation of toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS), which may be related to its anti-inflammatory effects. Furthermore, through lowering blood cholesterol, Fluvastatin also inhibits tubulointerstitial injury and prevents renal damage caused by high concentrations of the lipid.Fórmula:C24H25FNNaO4Pureza:Min. 98%Peso molecular:433.45 g/mol
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