CAS 94790-37-1

1-[Bis(dimetilamino)metileno]-1H-benzotriazolio hexafluorofosfato(1-) 3-óxido

Descripción:

1-[Bis(dimetilamino)metileno]-1H-benzotriazolio hexafluorofosfato(1-) 3-óxido, comúnmente conocido por su número CAS 94790-37-1, es un compuesto químico que presenta un moiety de benzotriazole, conocido por sus aplicaciones en diversos campos, incluyendo la síntesis orgánica y la ciencia de materiales. Este compuesto se caracteriza por su estructura única que incluye un grupo bis(dimetilamino)methylene, que contribuye a su reactividad y potencial como agente nucleofílico. La presencia del anión hexafluorofosfato indica interacciones iónicas fuertes, lo que puede mejorar la solubilidad en disolventes polares. Además, el grupo funcional 3-óxido puede conferir propiedades electrónicas específicas, haciéndolo útil en aplicaciones fotocatalíticas. El compuesto se maneja típicamente con cuidado debido a su potencial toxicidad y reactividad, y a menudo se utiliza en entornos de laboratorio controlados. Sus aplicaciones pueden extenderse a áreas como la catálisis, la síntesis de colorantes y como reactivo en transformaciones orgánicas, mostrando su versatilidad en la investigación y desarrollo químico.

Fórmula: C₁₁H₁₆N₅O·F₆P

InChI: InChI=1S/C11H16N5O.F6P/c1-13(2)11(14(3)4)15-9-7-5-6-8-10(9)16(17)12-15;1-7(2,3,4,5)6/h5-8H,1-4H3;/q+1;-1

Clave InChI: InChIKey=BSKUEERROYGAFF-UHFFFAOYSA-N

SMILES: C(N(C)C)(N(C)C)=[N+]1C=2C(N(=O)=N1)=CC=CC2.[P+5]([F-])([F-])([F-])([F-])([F-])[F-]

Sinónimos:

• 1-[Bis(dimethylamino)methylene]-1H-benzotriazolium hexafluorophosphate(1-) 3-oxide
• 1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, 3-oxide, hexafluorophosphate(1-) (1:1)
• 1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, hexafluorophosphate(1-), 3-oxide
• 2-(1H-Benzotriazole-1-Yl)-1,1,3,3-Tetramethyluronium Hexafluorophosphate
• Hbtu
• N-Hbtu
• N-[(1H-benzotriazol-1-yloxy)(dimethylamino)methylidene]-N-methylmethanaminium hexafluorophosphate
• O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium Hexafluorophosphate
• O-Benzotriazole-N,N,N',N'-tetramethyl-uronium-hexafluoro-phosphate
• O-Benzotriazole-N,N,N',N'-tetramethyl-uronium-hexafluorophosphate

HBTU [Coupling Reagent for Peptide]

CAS: 94790-37-1

Fórmula: C₁₁H₁₆F₆N₅OP

Pureza: >98.0%(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 379.25

Ref: 3B-B1657

1-(Bis(dimethylamino)methylene)-1H-benzo[d][1,2,3]triazole-1-ium 3-oxide hexafluorophosphate(V), 98%

CAS: 94790-37-1

Fórmula: C11H16F6N5OP

Forma y color: White - Almost white crystal - Powde

Peso molecular: 379.24

Ref: BD-BD23222

O-(Benzotriazol-1-yl)-N,N,N’,N’-tetramethyluronium hexafluorophosphate

CAS: 94790-37-1

Fórmula: C₁₁H₁₆F₆N₅OP

Pureza: 99.0%

Forma y color: Solid, Powder or Crystalline Powder or Solid

Peso molecular: 379.247

Ref: 10-F009019

O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 98%

CAS: 94790-37-1

O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate is used as a coupling reagent for solid-phase peptide synthesis. It has been shown to effectively suppress racemization. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. S

Fórmula: C₁₁H₁₆N₅O

Pureza: 98%

Forma y color: Crystalline powder, White to pale cream

Peso molecular: 234.28

Ref: 02-B23597

O-Benzotriazol-1-yl-N,N,N',N'-tetramethyluronium hexafluorophosphate

CAS: 94790-37-1

Fórmula: C₁₁H₁₆F₆N₅OP

Pureza: 98%

Forma y color: Solid

Peso molecular: 379.2418

Ref: IN-DA0035F7

HBTU

CAS: 94790-37-1

Fórmula: C₁₁H₁₆F₆N₅OP

Pureza: ≥ 99.0%

Forma y color: White to almost white powder or crystals

Peso molecular: 379.25

Ref: 7W-GE0864

O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate

CAS: 94790-37-1

O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate

Fórmula: C₁₁H₁₆N₅O·PF₆

Pureza: ≥95%

Forma y color: white crystals

Peso molecular: 379.24181g/mol

Ref: 54-PC6587

HBTU

CAS: 94790-37-1

HBTU is a common reagent used for peptide coupling, which can be employed for amide and ester formation. It is stable, highly reactive, suitable for solid phase and in-solution synthesis. The major advantages of HBTU are high yields, fast reaction times, easy reaction conditions, racemisation control and ease of purification from the water-soluble by-products. HBTU contains both the carbodiimide function and the benzotriazole one, activating the carboxylic acid and forming HOBt in situ. Although HBTU was originally catalogued as uronium salt, X-ray diffraction showed evidence for it to be an aminium salt instead.

Fórmula: C₁₁H₁₆F₆N₅OP

Pureza: Min. 99 Area-%

Peso molecular: 379.24 g/mol

Ref: 3D-Z-1021

HBTU Reagent

CAS: 94790-37-1

HBTU is a reagent that is used in the synthesis of peptides. It has been shown to have inhibitory properties and stable complexes with ester linkages. HBTU has been shown to have a negative effect on congestive heart disease, which may be due to its ability to bind to receptors and mimic the effects of peptide hormones. This compound is also used as a model system for mitochondrial membrane potential. HBTU binds covalently to the peptide hormone receptor, which slows down the rate of degradation and increases its resistance to proteases. HBTU can also be used as an immunosuppressant drug in animal models of autoimmune diseases by inhibiting T-cell proliferation and cytokine production.

Fórmula: C₁₁H₁₆N₅OPF₆

Pureza: Min. 95%

Peso molecular: 379.25 g/mol

Ref: 3D-KHB-1065-PI

HBTU

CAS: 94790-37-1

HBTU is a common reagent used for peptide coupling, which can be employed for amide and ester formation. It is stable, highly reactive, suitable for solid phase and in-solution synthesis. The major advantages of HBTU are high yields, fast reaction times, easy reaction conditions, racemisation control and ease of purification from the water-soluble by-products. HBTU contains both the carbodiimide function and the benzotriazole one, activating the carboxylic acid and forming HOBt in situ. Although HBTU was originally catalogued as uronium salt, X-ray diffraction showed evidence for it to be an aminium salt instead.

Fórmula: C₁₁H₁₆F₆N₅OP

Pureza: Min. 99 Area-%

Forma y color: White Powder

Peso molecular: 379.24 g/mol

Ref: 3D-FH07095

HBTU extrapure, 98%

CAS: 94790-37-1

Fórmula: C₁₁H₁₆F₆N₅OP

Pureza: min. 98 %

Forma y color: White, Crystalline powder

Peso molecular: 379.25

Ref: SR-44424

HBTU

CAS: 94790-37-1

Applications HBTU is a coupling reagent used in peptide synthesis. HBTU has been shown to effectively suppress racemization.
References Prasad, K.V.S.R.G. et al.: Int. J. Pharm. Sci. Rev. Res., 8, 108 (2011); Van Den Nest, W, et al.: J. Pep. Sci., 7, 115 (2001);

Fórmula: C₁₁H₁₆F₆N₅OP

Forma y color: White To Off-White

Peso molecular: 379.24

Ref: TR-H107500